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NiHowdy > Drug Classes > Nonsteroidal Anti-inflammatory Drug (NSAID)

Browse Medications by Drug Class: Nonsteroidal Anti-inflammatory Drug (NSAID)

Author

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed By

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked Fact checked

What are Nonsteroidal Anti-inflammatory Drug (NSAID)?

Nonsteroidal anti-inflammatory drugs (NSAIDs) are a class of medications used to reduce pain, inflammation, and fever. These medications work by inhibiting enzymes called cyclooxygenases (COX-1 and COX-2), which play a key role in producing prostaglandins, substances that mediate pain and inflammation in the body. NSAIDs are widely used to manage conditions like arthritis, menstrual pain, and acute injuries. A unique characteristic of NSAIDs is their versatility in treating both acute and chronic pain, making them a cornerstone of pain management worldwide. NiHowdy ensures affordable access to these essential medications, helping patients achieve relief and improved quality of life.

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List of drugs in Nonsteroidal Anti-inflammatory Drug (NSAID)

Drug NameMore InformationNiHowdy Prices & Bitcoin Rebate
AcioxiaAcioxia InformationAcioxia Pricing
AcularAcular InformationAcular Pricing
Acular LSAcular LS InformationAcular LS Pricing
AcuvailAcuvail InformationAcuvail Pricing
Anaprox DSAnaprox DS InformationAnaprox DS Pricing
Biifenac 1000Biifenac 1000 InformationBiifenac 1000 Pricing
Biifenac 500Biifenac 500 InformationBiifenac 500 Pricing
Bromfenac Sodium (Once-Daily)Bromfenac Sodium (Once-Daily) InformationBromfenac Sodium (Once-Daily) Pricing
BromSiteBromSite InformationBromSite Pricing
CambiaCambia InformationCambia Pricing
CapsFenac PakCapsFenac Pak InformationCapsFenac Pak Pricing
CapsinacCapsinac InformationCapsinac Pricing
CataflamCataflam InformationCataflam Pricing
CeleBREXCeleBREX InformationCeleBREX Pricing
CelecoxibCelecoxib InformationCelecoxib Pricing
DayproDaypro InformationDaypro Pricing
DermacinRx Lexitral PharmaPakDermacinRx Lexitral PharmaPak InformationDermacinRx Lexitral PharmaPak Pricing
DiclofenacDiclofenac InformationDiclofenac Pricing
Diclofenac EpolamineDiclofenac Epolamine InformationDiclofenac Epolamine Pricing
Diclofenac PotassiumDiclofenac Potassium InformationDiclofenac Potassium Pricing
Diclofenac Potassium(Migraine)Diclofenac Potassium(Migraine) InformationDiclofenac Potassium(Migraine) Pricing
Diclofenac SodiumDiclofenac Sodium InformationDiclofenac Sodium Pricing
Diclofenac Sodium ERDiclofenac Sodium ER InformationDiclofenac Sodium ER Pricing
DiclofonoDiclofono InformationDiclofono Pricing
Dicloheal-60Dicloheal-60 InformationDicloheal-60 Pricing
DiclonaDiclona InformationDiclona Pricing
DiclosaicinDiclosaicin InformationDiclosaicin Pricing
DicloStreamDicloStream InformationDicloStream Pricing
DiclotrexDiclotrex InformationDiclotrex Pricing
Diclotrex IIDiclotrex II InformationDiclotrex II Pricing
Diclovix MDiclovix M InformationDiclovix M Pricing
DiclozorDiclozor InformationDiclozor Pricing
DiflunisalDiflunisal InformationDiflunisal Pricing
DiMenthoDiMentho InformationDiMentho Pricing
DuexisDuexis InformationDuexis Pricing
EC-NaprosynEC-Naprosyn InformationEC-Naprosyn Pricing
EC-NaproxenEC-Naproxen InformationEC-Naproxen Pricing
ElyxybElyxyb InformationElyxyb Pricing
EsgicEsgic InformationEsgic Pricing
EtodolacEtodolac InformationEtodolac Pricing
Etodolac EREtodolac ER InformationEtodolac ER Pricing
FeldeneFeldene InformationFeldene Pricing
Fenoprofen CalciumFenoprofen Calcium InformationFenoprofen Calcium Pricing
FenorthoFenortho InformationFenortho Pricing
FlectorFlector InformationFlector Pricing
FlexipakFlexipak InformationFlexipak Pricing
FlurbiprofenFlurbiprofen InformationFlurbiprofen Pricing
Flurbiprofen SodiumFlurbiprofen Sodium InformationFlurbiprofen Sodium Pricing
FrotekFrotek InformationFrotek Pricing
IBUIBU InformationIBU Pricing
IbuprofenIbuprofen InformationIbuprofen Pricing
Ibuprofen-FamotidineIbuprofen-Famotidine InformationIbuprofen-Famotidine Pricing
Iclofenac CPIclofenac CP InformationIclofenac CP Pricing
IlevroIlevro InformationIlevro Pricing
IndocinIndocin InformationIndocin Pricing
IndomethacinIndomethacin InformationIndomethacin Pricing
Indomethacin ERIndomethacin ER InformationIndomethacin ER Pricing
InflammacinInflammacin InformationInflammacin Pricing
InflathermInflatherm InformationInflatherm Pricing
KetoprofenKetoprofen InformationKetoprofen Pricing
Ketoprofen ERKetoprofen ER InformationKetoprofen ER Pricing
Ketorolac TromethamineKetorolac Tromethamine InformationKetorolac Tromethamine Pricing
Lexitral PharmaPak IILexitral PharmaPak II InformationLexitral PharmaPak II Pricing
LicartLicart InformationLicart Pricing
LodineLodine InformationLodine Pricing
LofenaLofena InformationLofena Pricing
Meclofenamate SodiumMeclofenamate Sodium InformationMeclofenamate Sodium Pricing
Mefenamic AcidMefenamic Acid InformationMefenamic Acid Pricing
MeloxicamMeloxicam InformationMeloxicam Pricing
MobicMobic InformationMobic Pricing
NabumetoneNabumetone InformationNabumetone Pricing
NalfonNalfon InformationNalfon Pricing
NaprelanNaprelan InformationNaprelan Pricing
NaprosynNaprosyn InformationNaprosyn Pricing
NaproxenNaproxen InformationNaproxen Pricing
Naproxen SodiumNaproxen Sodium InformationNaproxen Sodium Pricing
Naproxen Sodium ERNaproxen Sodium ER InformationNaproxen Sodium ER Pricing
Naproxen-Esomeprazole MgNaproxen-Esomeprazole Mg InformationNaproxen-Esomeprazole Mg Pricing
NevanacNevanac InformationNevanac Pricing
NuDiclo SoluPakNuDiclo SoluPak InformationNuDiclo SoluPak Pricing
NuDiclo TabPakNuDiclo TabPak InformationNuDiclo TabPak Pricing
OmidriaOmidria InformationOmidria Pricing
OxaprozinOxaprozin InformationOxaprozin Pricing
PennsaicinPennsaicin InformationPennsaicin Pricing
PennsaidPennsaid InformationPennsaid Pricing
PiroxicamPiroxicam InformationPiroxicam Pricing
PrevidolRx AnalgesicPrevidolRx Analgesic InformationPrevidolRx Analgesic Pricing
PrevidolRx Plus AnalgesicPrevidolRx Plus Analgesic InformationPrevidolRx Plus Analgesic Pricing
ProfinacProfinac InformationProfinac Pricing
ProlensaProlensa InformationProlensa Pricing
Qmiiz ODTQmiiz ODT InformationQmiiz ODT Pricing
RelafenRelafen InformationRelafen Pricing
Relafen DSRelafen DS InformationRelafen DS Pricing
SalsalateSalsalate InformationSalsalate Pricing
SeglentisSeglentis InformationSeglentis Pricing
Sodium SalicylateSodium Salicylate InformationSodium Salicylate Pricing
SprixSprix InformationSprix Pricing
SulindacSulindac InformationSulindac Pricing
Sure Result DSS Premium PackSure Result DSS Premium Pack InformationSure Result DSS Premium Pack Pricing
TivorbexTivorbex InformationTivorbex Pricing
traMADol-AcetaminophentraMADol-Acetaminophen InformationtraMADol-Acetaminophen Pricing
VimovoVimovo InformationVimovo Pricing
VivlodexVivlodex InformationVivlodex Pricing
XrylixXrylix InformationXrylix Pricing
ZicloproZiclopro InformationZiclopro Pricing
ZipsorZipsor InformationZipsor Pricing
ZorvolexZorvolex InformationZorvolex Pricing

Brief history about Nonsteroidal Anti-inflammatory Drug (NSAID)?

The discovery of NSAIDs dates back to the 19th century, with acetylsalicylic acid (aspirin) being one of the first pain-relieving compounds derived from willow bark. In the 20th century, advancements in pharmacology led to the development of ibuprofen, naproxen, and other NSAIDs with improved safety profiles. The introduction of COX-2 inhibitors like celecoxib in the late 1990s offered targeted options for reducing inflammation while minimizing gastrointestinal side effects. Today, NSAIDs remain among the most commonly used medications globally. NiHowdy simplifies access to these trusted treatments, ensuring affordability for individuals seeking effective pain relief.

How do Nonsteroidal Anti-inflammatory Drug (NSAID) work?

NSAIDs work by inhibiting the activity of cyclooxygenase enzymes (COX-1 and COX-2). These enzymes are responsible for producing prostaglandins, which contribute to pain, inflammation, and fever. By blocking these enzymes, NSAIDs reduce the production of prostaglandins, alleviating symptoms like swelling, redness, and discomfort. For example, ibuprofen provides rapid relief from headaches and muscle pain, while celecoxib selectively targets COX-2, reducing inflammation with fewer gastrointestinal side effects. NiHowdy ensures patients can access these versatile medications affordably and conveniently.

What are Nonsteroidal Anti-inflammatory Drug (NSAID) used to treat?

Arthritis (Osteoarthritis and Rheumatoid Arthritis)

NSAIDs are commonly used to manage pain and inflammation associated with arthritis. They reduce joint swelling, stiffness, and discomfort, improving mobility and quality of life. Medications like celecoxib and naproxen are particularly effective for long-term management of these chronic conditions.

Acute Pain

For short-term relief of pain from injuries such as sprains, strains, or surgical recovery, NSAIDs like ibuprofen and ketorolac provide effective and rapid symptom control. They are often used as first-line treatments for mild to moderate acute pain.

Fever and Inflammation

NSAIDs, such as ibuprofen or naproxen, are widely used to relieve menstrual cramps by reducing uterine contractions and inflammation. These medications provide fast and effective relief, allowing individuals to continue their daily activities.

Menstrual Pain (Dysmenorrhea)

NSAIDs, such as ibuprofen or naproxen, are widely used to relieve menstrual cramps by reducing uterine contractions and inflammation. These medications provide fast and effective relief, allowing individuals to continue their daily activities.

Who should consider Nonsteroidal Anti-inflammatory Drug (NSAID) medications?

Adults

Adults with acute or chronic pain conditions benefit significantly from NSAIDs. These medications are effective for managing a range of issues, from arthritis and back pain to headaches and menstrual cramps. Healthcare providers tailor NSAID therapies to individual needs, considering factors like dosing and duration of use.

Children

Pediatric formulations of NSAIDs, such as ibuprofen, are safe and effective for managing fever, inflammation, and mild pain in children. Dosing is carefully adjusted based on the child's age and weight, ensuring optimal safety and efficacy.

Seniors

Seniors with chronic pain conditions, such as osteoarthritis, benefit from NSAIDs for symptom relief and improved mobility. However, age-related risks, such as gastrointestinal bleeding or kidney issues, necessitate careful monitoring and tailored dosing in this population.

Are Nonsteroidal Anti-inflammatory Drug (NSAID) safe?

NSAIDs are generally safe when used as directed, but they can cause side effects, especially with long-term use. Common issues include gastrointestinal discomfort, nausea, or heartburn. Serious risks include gastrointestinal ulcers, kidney damage, and cardiovascular events, particularly in individuals with pre-existing conditions. Regular follow-ups and adherence to recommended dosages minimize these risks.

Can I take Nonsteroidal Anti-inflammatory Drug (NSAID) during pregnancy?

NSAIDs are generally not recommended during pregnancy, particularly in the third trimester, as they may affect fetal development or prolong labor. Pregnant individuals should consult their healthcare provider to explore safer alternatives for managing pain or inflammation.

Are Nonsteroidal Anti-inflammatory Drug (NSAID) safe to take while lactating?

Certain NSAIDs, such as ibuprofen, are considered safe to use while breastfeeding due to minimal transfer into breast milk. However, patients should consult their healthcare provider to determine the best medication for their specific situation.

Are Nonsteroidal Anti-inflammatory Drug (NSAID) controlled substances?

NSAIDs are not classified as controlled substances. They are widely available over-the-counter for mild symptoms and by prescription for higher-strength formulations or chronic conditions. Proper use ensures safety and effectiveness.

Side effects of Nonsteroidal Anti-inflammatory Drug (NSAID)?

NSAIDs are effective but can cause side effects, especially with prolonged use or in high doses. Common side effects include nausea, heartburn, dizziness, and mild gastrointestinal discomfort. These are usually manageable with proper dosing and the use of medications like proton pump inhibitors (PPIs) for gastric protection. Less common side effects include fluid retention, increased blood pressure, or minor bleeding, particularly in individuals with pre-existing conditions like hypertension. These effects should be monitored by a healthcare provider. Rare but serious side effects include gastrointestinal ulcers, kidney damage, or cardiovascular events such as heart attack or stroke. Patients at higher risk should use NSAIDs under close medical supervision, with regular check-ups to monitor their health. Adherence to prescribed dosages and treatment durations minimizes the risk of side effects. Open communication with a healthcare provider ensures safe and effective use of NSAIDs.

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Cost considerations and insurance coverage for Nonsteroidal Anti-inflammatory Drug (NSAID)

The cost of NSAIDs varies depending on the specific medication and formulation. Over-the-counter options like ibuprofen and aspirin are affordable, while prescription-strength or specialized NSAIDs may be more expensive. Most insurance plans cover NSAIDs for chronic conditions or specific indications. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these essential medications remain accessible and cost-effective.

How do I get rebates on Nonsteroidal Anti-inflammatory Drug (NSAID)?

NiHowdy's Bitcoin rebate program for NSAID prescriptions provides patients with a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing pain and inflammation both affordable and rewarding, improving access to effective treatments while building long-term value.

Medical Conditions treated by Nonsteroidal Anti-inflammatory Drug (NSAID)

Everyday Health Concerns related to Nonsteroidal Anti-inflammatory Drug (NSAID)