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Acular
Acular (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the temporary relief of pain and inflammation in the eyes. It is commonly used after cataract surgery and for managing seasonal allergic conjunctivitis. Acular works by reducing inflammation and providing analgesia, helping to alleviate discomfort and promote healing following ocular procedures.
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Frequently Asked Questions
How long does it take for Acular to work?
Acular typically begins to relieve pain and inflammation within a few hours of application, but individual response times may vary.
Can I use Acular with contact lenses?
It is recommended to remove contact lenses before applying Acular and wait at least 15 minutes before reinserting them to avoid potential irritation.
What should I do if I miss a dose of Acular?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Is Acular safe for long-term use?
Acular is intended for short-term use following cataract surgery or for managing allergic conjunctivitis. Long-term use should be monitored by a healthcare provider due to potential side effects.
Can I take other medications while using Acular?
Always inform your healthcare provider about all medications you are taking, including over-the-counter drugs, to avoid potential interactions.
Comprehensive Drug Guide
How Does Acular Work?
Acular works by inhibiting the cyclooxygenase (COX) enzymes involved in the synthesis of prostaglandins, which are mediators of inflammation and pain. By reducing the levels of these inflammatory substances in the ocular tissues, Acular decreases pain and swelling associated with ocular surgery and allergic reactions.
Common Dosages
- Ophthalmic solution: 0.4% ketorolac tromethamine
Typical Dosing
- For postoperative inflammation, the typical dose is one to two drops instilled into the affected eye(s) four times daily, starting 24 hours after surgery and continuing through the first two weeks of recovery.
- For allergic conjunctivitis, instill one to two drops in the affected eye(s) four times daily as needed.
Typical Dosing
FDA Approved Indications
- Postoperative inflammation following cataract surgery
- Allergic conjunctivitis for the temporary relief of eye itching and redness
Who Shouldn't Take Acular?
- Known hypersensitivity to ketorolac or any components of the formulation
- Active or history of recurrent peptic ulcer disease or gastrointestinal bleeding
- Severe renal impairment
Advice From The Pharmacist
- Use Acular exactly as prescribed, ensuring proper technique for eye drop administration.
- Avoid touching the dropper tip to any surface, including the eye, to prevent contamination.
- Monitor for signs of allergic reactions or irritation; discontinue use and contact your healthcare provider if these occur.
- Avoid wearing contact lenses while using Acular, as they can exacerbate irritation.
Side Effects of Acular
Common Side Effects
- Burning or stinging upon application
- Redness of the eye
- Dry eyes
- Itching or discomfort in the eyes
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, itching, swelling, or difficulty breathing)
- Corneal edema or other serious ocular conditions
Risks and Warnings of Acular
- Corneal Effects: Prolonged use of NSAIDs in the eye may lead to corneal complications. Patients should be monitored for signs of corneal damage.
- Systemic Absorption: Although Acular is applied topically, systemic absorption can occur. Caution should be exercised in patients with a history of cardiovascular disease, renal impairment, or gastrointestinal disorders.
- Allergic Reactions: Patients should be aware of the potential for allergic reactions and report any unusual symptoms to their healthcare provider.
Interactions with Acular
Common Drug Interactions
- Other Ocular Medications: When using multiple ophthalmic medications, allow at least 5 minutes between applications to prevent interactions.
- NSAIDs: Patients should avoid using other NSAIDs concurrently to reduce the risk of adverse effects.
Alternatives to Acular
- Other NSAID eye drops: Such as diclofenac or flurbiprofen, may be used for similar indications.
- Corticosteroid eye drops: These may be considered for inflammation management in specific cases.
- Topical antihistamines: For allergic conjunctivitis, alternative options may include antihistamine eye drops.
