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Diclofenac
Diclofenac falls within the Nonsteroidal AntiInflammatory Drugs (NSAIDs) category. It lessens inflammation and associated pain. It's commonly prescribed for conditions that cause inflammation and discomfort, like arthritis, migraines, and some postoperative pains. Some of the common side effects are upset stomach, nausea, and diarrhea. Your healthcare provider will evaluate these potential outcomes before prescribing this medication.
Drug Class: Prostaglandin Analog
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Frequently Asked Questions
Can Diclofenac affect my fertility? I missed a dose of Diclofenac, what should I do?
Yes, Diclofenac can temporarily affect your fertility. If you're planning a pregnancy, consult with your doctor.
Can Diclofenac affect my fertility? I missed a dose of Diclofenac, what should I do?
Yes, Diclofenac can temporarily affect your fertility. If you're planning a pregnancy, consult with your doctor.
Can I consume alcohol while on Diclofenac?
It's better to avoid alcohol as this combination can increase the risk of gastrointestinal bleeding.
Can I consume alcohol while on Diclofenac?
It's better to avoid alcohol as this combination can increase the risk of gastrointestinal bleeding.
Can I drink alcohol while on Diclofenac?
Drinking alcohol while taking diclofenac can significantly increase the risk of gastrointestinal side effects, so it's best to limit alcohol intake.
Can I just stop taking Diclofenac all of a sudden?
Never stop taking diclofenac without consultation from your doctor. This is necessary to avoid withdrawal symptoms.
Can I take Diclofenac if I have asthma?
It's best to talk to your doctor first as diclofenac may cause asthma triggers in some individuals.
Can I take Diclofenac while pregnant?
Diclofenac should be avoided especially in the third trimester of pregnancy unless the benefits outweigh the potential risks. Always consult your healthcare provider.
I missed a dose of Diclofenac, what should I do?
If you've missed a dose, take it as soon as you remember. But if it's close to your next dose, skip the missed one. Avoid taking two doses at once to compensate for the missed dose.
If you've missed a dose, take it as soon as you remember. But if it's close to your next dose, skip the missed one. Avoid taking two doses at once to compensate for the missed dose.
What should I do if I take an overdose?
What should I do if I take an overdose?
If you've taken more than the prescribed dose, seek immediate medical attention. Signs of an overdose include stomach pain, nausea, vomiting, and lethargy.
Will Diclofenac affect my blood pressure?
Although rare, diclofenac can elevate blood pressure. If you suffer from high blood pressure, make sure to monitor your levels regularly.
Comprehensive Drug Guide
How Does Diclofenac Work?
It inhibits cyclooxygenase (COX), an enzyme crucial to the production of prostaglandins that cause inflammation and pain.
What is Diclofenac Used For?
FDA indications: Primarily used to manage arthritis pains, menstrual cramps, migraines, and postoperative pain.
Offlabel uses: Sometimes used for gout attacks or managing pain due to kidney stones.
Common Dosages
Tablets: 50mg, 100mg
Topical solutions and gels available for local application.
Typical Dosing
FDA Approved Indications
- For arthritis: 50mg 23 times daily
- For acute pain: 50mg every 8 hours
- For menstrual pain: 50mg three times daily
Who Shouldn't Take Diclofenac?
- If you have had or are at risk of cardiovascular events (heart attack and stroke).
- If you've had gastric ulcers or have a history of gastric problems.
- If you are allergic to other NSAIDs or aspirin.
- If you suffer from severe kidney or liver diseases.
- If you have serious skin conditions like StevensJohnson syndrome.
- If pregnant or breastfeeding, unless prescribed under close medical supervision.
- If suffering from uncontrolled hypertension.
Advice From The Pharmacist
- Take Diclofenac with food or milk to avoid an upset stomach.
- Avoid alcohol as it can boost your risk of stomach bleeding.
- Consult with a healthcare provider before taking other pain medicines alongside Diclofenac.
- Do not take Diclofenac just before or after heart surgery. Always consult with your doctor first.
- Do not use Diclofenac for more extended periods unless directed by your healthcare provider.
- Seek immediate medical attention if you experience chest pains, shortness of breath, or sudden weakness, or difficulties with vision or speech.
Side Effects of Diclofenac
Common Side Effects
- You may experience nausea, heartburn, or stomach upset (try taking it with food)
- Mild diarrhea is also common
Uncommon/Severe Side Effects
- Uncommon side effects:
- Tiredness
- Allergic reactions
- Severe side effects:
- Shortness of breath
- Chest pain
- Swelling of legs
- Irritated veins where the drug is injected
Risks and Warnings of Diclofenac
- Cardiovascular Risk: Diclofenac may increase the risk of serious and potentially fatal cardiovascular thrombotic events, such as heart attack or stroke. The risk can occur early in treatment and may increase with duration of use and in patients with preexisting cardiovascular disease or risk factors. Diclofenac is contraindicated for the treatment of perioperative pain in coronary artery bypass graft surgery (CABG).
- Gastrointestinal Risk: Diclofenac can cause serious stomach or intestinal problems like ulcers, bleeding, or holes. The risk can happen without warning symptoms at any time during treatment and may increase with longer use of the drug. Elderly patients are at greater risk.
Interactions with Diclofenac
Common Drug Interactions
- Blood thinners: Warfarin, Heparin
- Other NSAIDs: Aspirin, Ibuprofen
- Steroids: predniSONE
- Antidepressants: Fluoxetine, Escitalopram
