Ibuprofen

• Pain and Fever in Adults:
• Over-the-counter (OTC): 200 to 400 mg every 4 to 6 hours as needed. Do not exceed 1,200 mg in 24 hours unless directed by a doctor.
• Prescription: Dosages can go up to 800 mg, taken up to four times a day (3,200 mg/day), but this is under the direction of a healthcare professional.
• Osteoarthritis and Rheumatoid Arthritis in Adults: Typically, 400-800 mg every 6-8 hours. However, the dosing can vary based on severity, and the maximum is typically limited to 3,200 mg/day.

• Migraine: Adults might take 400800 mg at the onset of symptoms, repeated every 68 hours as needed.
• Juvenile Arthritis: Dosing is individualized, often similar to the pediatric dosing for pain and fever but might be adjusted based on the child's specific needs and the severity of the condition.
• Premenstrual Syndrome (PMS) and Dysmenorrhea: Similar to pain dosing in adults: 200400 mg every 4 to 6 hours as needed.
• Patent Ductus Arteriosus: This would be administered in a hospital setting with dosing based on the infant's weight and specific medical needs.
• Muscle Pain and Soft Tissue Injuries: Typically follows standard pain dosing recommendations.

Dosing is often determined by weight rather than age. Generally, it's around 510 mg/kg every 68 hours, but not to exceed 40 mg/kg in 24 hours.

• People with a history of gastrointestinal ulcers or bleeding.
• Individuals with a history of asthma or aspirin sensitivity, as they may be at a higher risk of experiencing an allergic reaction or respiratory issues.
• Pregnant women in the third trimester, as it may affect the baby's circulation and cause other complications.
• Individuals with liver or kidney disease, as ibuprofen can put additional stress on these organs.
• People taking bloodthinning medications or with bleeding disorders, as ibuprofen can increase the risk of bleeding.

• Take ibuprofen with food to help prevent stomach upset.
• Drink plenty of water when taking ibuprofen to stay hydrated.
• Follow the recommended dosage and do not exceed the maximum daily limit.
• If you have any medical conditions or are taking other medications, check with a healthcare provider or pharmacist before using ibuprofen.
• If your symptoms persist or worsen despite taking ibuprofen, consult a healthcare provider for further evaluation.

• Upset stomach or indigestion
• Heartburn
• Mild headache
• Dizziness or lightheadedness

• Stomach ulcers or bleeding: Signs may include black, tarry stools, abdominal pain, or vomiting blood.
• Kidney problems: Symptoms can include decreased urine output, swelling in the feet or ankles, or unexplained weight gain.
• Liver problems: Indicators may include yellowing of the skin or eyes, dark urine, or persistent fatigue.

• Individuals with a history of stomach ulcers, heart conditions, high blood pressure, kidney or liver problems, or asthma should use ibuprofen with caution and consult their healthcare provider before taking it regularly.
• Longterm use of ibuprofen can increase the risk of kidney damage, so it's advisable to limit prolonged use.
• If you experience any unusual symptoms or side effects while taking ibuprofen, such as severe stomach pain, difficulty breathing, or swelling, seek medical attention promptly.
• Avoid taking ibuprofen if you are pregnant, in the third trimester, or breastfeeding without consulting with a healthcare provider first.

• Aspirin
• Warfarin
• Lithium
• Methotrexate
• ACE inhibitors (e.g., lisinopril, enalapril)
• Diuretics (e.g., furosemide, hydrochlorothiazide)
• Selective serotonin reuptake inhibitors (SSRIs) (e.g., fluoxetine, sertraline)
• Corticosteroids (e.g., prednisone, dexamethasone)
• Anticoagulants (e.g., rivaroxaban, apixaban)
• Antiplatelet drugs (e.g., clopidogrel, ticagrelor)

• Acetaminophen (Tylenol)
• Naproxen (Aleve)
• Aspirin (Bayer, Ecotrin)
• Celecoxib (Celebrex)
• Diclofenac (Voltaren)
• Meloxicam (Mobic)
• Ketorolac (Toradol)