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hydroCHLOROthiazide

Hydrochlorothiazide, often known as HCTZ, is a common diuretic (or "water pill") used widely for the treatment of conditions such as high blood pressure, edema (swelling), and heart failure. It gets to work by making you urinate more to shed excess water and salt from your body. Side effects could include dizziness, bruising, slow healing, and photosensitivity, but your doctor will make sure the pluses overshadow such negatives.

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Frequently Asked Questions

Can I use Hydrochlorothiazide if I have diabetes?
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Yes, but it can increase your blood sugar levels, so it?s important to monitor your blood sugar regularly and inform your doctor if you notice significant changes.

Can I use Hydrochlorothiazide if I have diabetes?
Open FAQClose FAQ

Yes, but it can increase your blood sugar levels, so it ??s important to monitor your blood sugar regularly and inform your doctor if you notice significant changes.

Does Hydrochlorothiazide result in weight loss?
Open FAQClose FAQ

It could cause some initial weight loss due to its diuretic effect, which leads to the elimination of water and salt from your body.

Does Hydrochlorothiazide result in weight loss?
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It could cause some initial weight loss due to its diuretic effect, which leads to the elimination of water and salt from your body.

What if I accidentally skip a dose of Hydrochlorothiazide?
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Take the missed dose as soon as you remember, unless it?s nearly time for your next planned dose ? in such cases, skip the missed dose altogether. Don't take double doses to make up for a missed one.

What if I accidentally skip a dose of Hydrochlorothiazide?
Open FAQClose FAQ

Take the missed dose as soon as you remember, unless it ??s nearly time for your next planned dose ?? in such cases, skip the missed dose altogether. Don't take double doses to make up for a missed one.

Comprehensive Drug Guide

How Does hydroCHLOROthiazide Work?

Hydrochlorothiazide functions as a diuretic by inhibiting sodium reabsorption in the distal renal tubules. This results in increased excretion of sodium ions and subsequent water, which in turn reduces plasma volume and lowers blood pressure.

What is hydroCHLOROthiazide Used For?

FDA indications: HCTZ is primarily used to treat high blood pressure (hypertension) and alleviate the symptoms of fluid retention (edema) in conditions like congestive heart failure, cirrhosis, or kidney disorders.

Offlabel uses: It’s also used offlabel for treating osteoporosis, as it helps in increasing the body’s calcium levels.

Common Dosages

Tablets: 12.5mg, 25mg, 50mg, 100mg.

Capsules: 12.5mg.

Typical Dosing

FDA Approved Indications

Hypertension: Start at 25mg to 50mg per day, either as a single dose or divided doses.

Edema: Start at 25mg to 100mg per day in divided doses.

Who Shouldn't Take hydroCHLOROthiazide?

  • People allergic to hydrochlorothiazide or sulfa drugs.
  • Patients with kidney disease or unable to urinate.
  • People suffering from liver diseases.
  • Pregnant women, especially in their second and third trimesters.
  • People with gout.
  • Anyone under treatment for lupus.
  • Diabetics who have trouble controlling their blood sugar.

Advice From The Pharmacist

  • Always consume HCTZ with food to avoid an upset stomach.
  • Avoid taking Hydrochlorothiazide close to your bedtime to prevent nocturnal urination.
  • It’s crucial not to stop taking this medicine suddenly unless your doctor tells you to do so.
  • Do not consume alcohol while taking hydrochlorothiazide, as it can worsen certain Hydrochlorothiazide side effects.
  • Drink ample water unless your doctor advises otherwise.
  • If you frequently experience dehydration symptoms like extreme thirst, very dry mouth, muscle cramps, nausea, or vomiting, tell your doctor right away.
  • Stay vigilant for signs of high blood sugar like increased thirst and urination.
  • Regularly check your blood pressure.
  • Protect your skin from the sun, as Hydrochlorothiazide can make your skin more sensitive to sunlight.

Side Effects of hydroCHLOROthiazide

Common Side Effects

  • Blurred vision or light sensitivity.
  • Loss of appetite, stomach upset.
  • Mild skin rash.

Uncommon/Severe Side Effects

  • Uncommon side effects:
  • Severe stomach pain (with or without nausea or vomiting).
  • Difficulty or pain swallowing, sore throat.
  • Unusual bleeding or bruising.
  • Rare side effects:
  • Extreme tiredness or weakness.
  • Fever or chills.
  • Severe side effects:
  • Yellowing of the eyes or skin.
  • A sign of severe allergic reactions such as rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, and troubled breathing.

Interactions with hydroCHLOROthiazide

Common Drug Interactions

  • Digoxin
  • Lithium
  • Antidiabetic drugs (including insulin)
  • Nonsteroidal antiinflammatory drugs (such as ibuprofen)
  • Alcohol
  • Barbiturates (like phenobarbital)

Alternatives to hydroCHLOROthiazide

  • Furosemide (Lasix)
  • Spironolactone (Aldactone)
  • Bumetanide (Bumex)
  • Amiloride (Midamor)
  • Metolazone (Zaroxolyn)