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Furosemide
Furosemide is a diuretic, known popularly as a "water pill". It helps your body get rid of extra water and salt. It's used to treat conditions like heart failure, kidney disease, and high blood pressure.
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Frequently Asked Questions
Can I take furosemide if I have gout?
Furosemide can lead to increased uric acid levels, which can cause or worsen gout. Talk to your doctor about this if you have a history of gout.
Does furosemide make you lose weight?
It can lead to weight loss due to fluid loss, but it's not suitable for long-term weight management.
I missed a dose, what do I do?
Take it as soon as you remember unless it's time for your next dose. Never double dose to compensate for a missed one.
Can I just stop taking this medication?
Stopping suddenly can cause serious problems, like a rapid increase in blood pressure. Always follow your doctor's instructions about how to safely discontinue this medication.
Is it okay to drink alcohol while taking furosemide?
It's best to avoid it as alcohol can interfere with how the medication works and might also contribute to certain side effects like dizziness and dehydration.
Comprehensive Drug Guide
How Does Furosemide Work?
Furosemide is a powerful diuretic. It works by inhibiting the reabsorption of sodium and chloride in the thick ascending limb of the Loop of Henle, resulting in increased urine output.
What is Furosemide Used For?
Furosemide is used to treat fluid build-up due to heart failure, kidney disease, or liver scarring. Also, it treats high blood pressure.
Common Dosages
- Tablets: 20mg, 40mg, 80mg
- Oral solution: 10mg/mL
Typical Dosing
FDA Approved Indications
- For fluid build-up in adults: Start with 20 to 40mg once daily, then adjust based on the response.
- For hypertension in adults: Usually, 40mg twice daily to start, but doses could be from 20 to 80mg.
Pediatric Dosing
Pediatric dosing is weight-based, typically around 1 to 2mg per kg of body weight once daily.
Who Shouldn't Take Furosemide?
- Those allergic to it or any of its components.
- Those with an inability to urinate.
- Those who have severe kidney disease and can't make urine or clear waste properly.
- Those with hypokalemia (low blood potassium levels) or hyponatremia (low blood sodium levels).
- Those with hyperuricemia (high levels of uric acid in the body) causing gout.
- Those with severe liver disease leading to hepatic coma.
- Pregnant or planning to become pregnant.
- Breastfeeding mothers.
Advice From The Pharmacist
- Stay hydrated. Furosemide can make you pee a lot and could lead to dehydration.
- Check your weight regularly. Dropping pounds too quickly could be a sign you're losing too much water, which needs medical attention.
- Take it easy in the sun. Furosemide can make your skin more sensitive to sunlight.
- Watch your diet. Furosemide can cause low levels of potassium, calcium, and magnesium. Eat foods rich in these nutrients or ask your doctor about supplements.
- If you feel lightheaded or dizzy, make sure to sit or lie down until the feeling passes.
- Reach out to your doctor if you notice muscle cramps or weakness, an irregular heartbeat, and unusual fatigue or confusion.
Side Effects of Furosemide
Common Side Effects
- You might pee a lot more and feel thirsty.
- You might feel dizzy or lightheaded, especially if you stand up too fast.
- You might have a headache.
Uncommon/Severe Side Effects
- You might have a fever or sore throat, hearing problems, or ringing in the ears.
- You may experience severe stomach or abdominal pain, persistent nausea, or vomiting.
- Muscle cramps, weakness, or spasms.
- Unusual tiredness, and mental mood changes.
- Unusual decrease in the amount of urine, dark urine, yellowing eyes, or skin.
- Signs of a severe allergic reaction like rash, itching/swelling of the face/tongue/throat, severe dizziness, and difficulty breathing.
Risks and Warnings of Furosemide
- Use with caution in hepatic cirrhosis, as alterations in the electrolyte balance may precipitate hepatic encephalopathy.
- Prolonged use can result in dehydration and electrolyte imbalance.
- Measure potassium levels as furosemide could cause hypokalemia.
Interactions with Furosemide
Common Drug Interactions
- Digoxin
- Lithium
- Phenytoin
- Cisplatin
- Antibiotics (like gentamicin, tobramycin)
- Anti-hypertensives and other diuretics
Alternatives to Furosemide
- Hydrochlorothiazide
- Bumetanide
- Torsemide
- Chlorthalidone
- Spironolactone
