You're not logged in. Please log in to earn stock or Bitcoin rewards on your prescription purchase.
CeleBREX
CeleBREX is a nonsteroidal anti-inflammatory drug (NSAID) that contains celecoxib, primarily used to relieve pain and inflammation. It is commonly prescribed for conditions like osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and menstrual pain (dysmenorrhea). Celecoxib works by inhibiting COX-2, an enzyme responsible for the production of substances in the body that cause pain and inflammation.
Rx. Enter your prescription
How would you like to get your prescription? Select an option
Pharmacy pickup
Select from 35,000 pharmacies
Free two-day delivery
Coming soon!
Find a pharmacy near you. Enter your ZIP code
Are you a member? Sign up or log in.
Members have saved
$NaN
using our savings card for instant savings.
Don't pay full retail price and miss out on potential savings. Try it now—you have nothing to lose!
NaNM
worth of Satoshi has been rewarded to our members.
Everyone who signs up enjoys the benefits of earning FREE Bitcoin with every purchase.
How much Bitcoin can you earn with CeleBREX ?
The potential for Bitcoin rewards to increase and appreciate in value is a possibility to consider, which may occur over time.
See the value of your savings today
Today's Value
1 Bitcoin = $NaN
Bitcoin (BTC)
...
USD
$NaN
Adjust Bitcoin's potential value to see how much it could be worth
Potential Value
1 Bitcoin =
Bitcoin (BTC)
...
USD
$NaN
Frequently Asked Questions
How long does it take for CeleBREX to start working?
CeleBREX typically starts working within a few hours of taking the first dose. However, it may take a few days to feel the full effects, particularly for conditions like arthritis.
Can I take CeleBREX if I have a history of stomach ulcers?
While CeleBREX has a lower risk of causing gastrointestinal issues compared to non-selective NSAIDs, it can still cause ulcers or gastrointestinal bleeding, especially in patients with a history of ulcers. It is important to discuss your medical history with your doctor before starting CeleBREX.
Is CeleBREX safer for the stomach compared to other NSAIDs?
CeleBREX selectively inhibits COX-2, which is associated with inflammation, while sparing COX-1, which protects the stomach lining. This makes it less likely to cause stomach irritation or ulcers compared to non-selective NSAIDs, but the risk still exists.
What should I do if I miss a dose of CeleBREX?
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and take the next one at your regular time. Do not take two doses at the same time.
Can CeleBREX be used long-term for arthritis?
CeleBREX can be used long-term for chronic conditions like osteoarthritis or rheumatoid arthritis, but it should be used at the lowest effective dose to minimize the risk of cardiovascular and gastrointestinal side effects. Regular monitoring by a healthcare provider is recommended.
Can I take CeleBREX with other pain relievers?
You should avoid taking CeleBREX with other NSAIDs like ibuprofen or naproxen. However, you can take it with acetaminophen (Tylenol) if needed for additional pain relief. Always consult your healthcare provider before combining medications.
Is CeleBREX safe during pregnancy?
CeleBREX is not recommended during pregnancy, particularly during the third trimester, as it can cause harm to the unborn baby. Consult your doctor if you are pregnant or planning to become pregnant while using CeleBREX.
Comprehensive Drug Guide
How Does CeleBREX Work?
CeleBREX works by selectively inhibiting the COX-2 enzyme, reducing the production of prostaglandins that cause inflammation and pain. By targeting COX-2, it reduces pain and swelling while having a reduced impact on COX-1, which is involved in protecting the stomach lining, thereby lowering the risk of gastrointestinal side effects compared to non-selective NSAIDs.
Common Dosages
- Osteoarthritis: 200 mg once daily or 100 mg twice daily.
- Rheumatoid Arthritis: 100 to 200 mg twice daily.
- Acute Pain or Dysmenorrhea: Initial dose of 400 mg, followed by an additional 200 mg if needed on the first day, then 200 mg twice daily as needed.
- Ankylosing Spondylitis: 200 mg daily, either as a single dose or 100 mg twice daily.
Typical Dosing
- Administration: CeleBREX is taken orally with or without food. Patients who are prone to stomach upset are advised to take it with food to minimize gastrointestinal discomfort.
- Frequency: It is typically taken once or twice daily, depending on the condition being treated.
- Duration of Use: The duration of use depends on the condition being treated. For chronic conditions such as arthritis, it is often taken long-term under medical supervision.
Typical Dosing
FDA Approved Indications
- Osteoarthritis: Relief of signs and symptoms of osteoarthritis.
- Rheumatoid Arthritis: Relief of signs and symptoms of rheumatoid arthritis in adults.
- Juvenile Rheumatoid Arthritis: In patients aged 2 years and older.
- Ankylosing Spondylitis: Treatment of signs and symptoms of ankylosing spondylitis.
- Acute Pain: Management of acute pain in adults.
- Primary Dysmenorrhea: Relief of menstrual cramps and pain.
Who Shouldn't Take CeleBREX?
- Hypersensitivity to celecoxib or other NSAIDs.
- History of allergic reactions to sulfonamides (sulfa drugs).
- History of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs.
- Coronary artery bypass graft (CABG) surgery: CeleBREX should not be used for pain after heart surgery.
- Severe hepatic impairment.
- Known gastrointestinal bleeding or ulceration.
Advice From The Pharmacist
- Take the lowest effective dose for the shortest duration possible to minimize the risk of cardiovascular and gastrointestinal side effects.
- Avoid taking CeleBREX with other NSAIDs, including over-the-counter pain relievers like ibuprofen or naproxen, to prevent an increased risk of side effects.
- Be aware of signs of gastrointestinal bleeding, such as black or tarry stools, and report them to a healthcare provider.
- Inform their healthcare provider if they have a history of heart disease, high blood pressure, or kidney problems.
- Stay well-hydrated, especially in older adults, to reduce the risk of kidney damage.
Side Effects of CeleBREX
Common Side Effects
- Stomach pain
- Diarrhea
- Indigestion or heartburn
- Gas or bloating
- Dizziness
- Swelling in the hands, feet, or legs
Uncommon/Severe Side Effects
- Cardiovascular Events: Increased risk of heart attack or stroke, especially with long-term use or in patients with pre-existing heart disease.
- Gastrointestinal Bleeding: Symptoms include black or tarry stools, vomiting blood, or severe abdominal pain.
- Kidney Damage: Decreased urine output or swelling in the extremities.
- Liver Issues: Symptoms include yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Allergic Reactions: Rash, itching, or difficulty breathing.
Risks and Warnings of CeleBREX
- Cardiovascular Risk: CeleBREX may increase the risk of serious cardiovascular events, including heart attack and stroke, particularly with long-term use or in patients with cardiovascular disease. It should be used cautiously in patients with known risk factors for heart disease.
- Gastrointestinal Risk: Though CeleBREX has a lower risk of causing ulcers and gastrointestinal bleeding than non-selective NSAIDs, the risk still exists, particularly in older adults or those with a history of ulcers.
- Kidney and Liver Function: Patients with kidney or liver impairments should use CeleBREX cautiously and under medical supervision, as it can worsen these conditions.
- Allergic Reactions: CeleBREX contains a sulfa component, so patients with sulfonamide allergies should avoid it.
Interactions with CeleBREX
Common Drug Interactions
- Anticoagulants (e.g., warfarin): May increase the risk of bleeding.
- Aspirin: Can increase the risk of gastrointestinal bleeding when used with CeleBREX.
- ACE Inhibitors and ARBs: May reduce the effectiveness of blood pressure medications and increase the risk of kidney damage.
- Diuretics: May reduce kidney function, especially in dehydrated patients.
- Lithium: CeleBREX may increase lithium levels in the blood, leading to toxicity.
- Fluconazole: May increase the levels of CeleBREX in the blood.
Alternatives to CeleBREX
- Other NSAIDs: Such as ibuprofen or naproxen, which are also used for pain and inflammation but are non-selective COX inhibitors.
- Acetaminophen (Tylenol): For pain relief in patients who cannot tolerate NSAIDs.
- Corticosteroids: Such as prednisone, for inflammation related to autoimmune diseases.
- Opioids: For short-term, severe pain management, though these carry risks of dependence and other side effects.
