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Vivlodex
Vivlodex (generic name: meloxicam) is a nonsteroidal anti-inflammatory drug (NSAID) used to manage pain and inflammation associated with osteoarthritis. It works by reducing hormones in the body that cause pain and inflammation. Vivlodex is specifically formulated as a low-dose NSAID to minimize the risk of gastrointestinal side effects, while still providing effective pain relief for individuals with osteoarthritis.
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Frequently Asked Questions
How long does it take for Vivlodex to work?
Vivlodex may begin to relieve pain and inflammation within a few hours of taking the first dose, but it may take several days of consistent use to feel the full effects.
Can I take Vivlodex with other pain medications?
Avoid taking Vivlodex with other NSAIDs (e.g., ibuprofen, aspirin), but acetaminophen may be safe to use for additional pain relief. Always consult your doctor before combining medications.
Is Vivlodex safe for long-term use?
Long-term use of Vivlodex can increase the risk of serious side effects, such as gastrointestinal bleeding and cardiovascular events. Your doctor will monitor your condition and adjust treatment as necessary.
What should I do if I miss a dose of Vivlodex?
If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take extra doses to make up for a missed one.
Can Vivlodex cause stomach problems?
Yes, like other NSAIDs, Vivlodex can cause stomach problems such as indigestion, ulcers, and bleeding. Taking it with food and following your doctor’s instructions can help reduce the risk of these side effects.
Comprehensive Drug Guide
How Does Vivlodex Work?
Vivlodex (meloxicam) works by inhibiting the activity of cyclooxygenase (COX) enzymes, particularly COX-2, which play a key role in the production of prostaglandins. Prostaglandins are compounds that promote inflammation, pain, and fever. By reducing their production, Vivlodex helps relieve pain and decrease inflammation associated with osteoarthritis.
Common Dosages
- 5 mg capsules
- 10 mg capsules
Typical Dosing
- The usual starting dose of Vivlodex is 5 mg once daily, with the option to increase to 10 mg once daily based on the patient's response to treatment and tolerance. It is typically taken with food or as directed by a healthcare provider.
Typical Dosing
FDA Approved Indications
- Relief of the signs and symptoms of osteoarthritis in adults.
Who Shouldn't Take Vivlodex?
- Known hypersensitivity to meloxicam or other NSAIDs
- A history of asthma, urticaria, or allergic reactions to aspirin or other NSAIDs
- Active gastrointestinal bleeding or ulcers
- Severe kidney or liver disease
Advice From The Pharmacist
- Take Vivlodex with food or milk to reduce the risk of gastrointestinal discomfort or ulcers.
- Avoid taking other NSAIDs (such as ibuprofen or aspirin) while using Vivlodex, as this may increase the risk of side effects.
- If you experience symptoms such as chest pain, shortness of breath, weakness, or slurred speech, seek medical attention immediately as these could indicate serious cardiovascular side effects.
Side Effects of Vivlodex
Common Side Effects
- Upset stomach or indigestion
- Diarrhea
- Nausea
- Dizziness
- Headache
Uncommon/Severe Side Effects
- Gastrointestinal bleeding or ulcers
- Heart attack or stroke
- Kidney damage or failure
- Severe allergic reactions (rash, swelling, difficulty breathing)
Risks and Warnings of Vivlodex
- Cardiovascular Risk: NSAIDs, including Vivlodex, can increase the risk of serious cardiovascular events such as heart attack or stroke, especially with prolonged use or in individuals with existing heart conditions.
- Gastrointestinal Risk: Vivlodex may cause stomach ulcers, bleeding, or perforation, which can be life-threatening. These risks are higher in older adults and those with a history of GI issues.
- Renal Toxicity: NSAIDs can lead to kidney damage, especially in individuals with pre-existing kidney conditions or those who take the medication for extended periods.
Interactions with Vivlodex
Common Drug Interactions
- Blood Thinners: Vivlodex may increase the risk of bleeding when taken with anticoagulants such as warfarin.
- Other NSAIDs: Concurrent use of other NSAIDs, including aspirin, may increase the risk of gastrointestinal side effects.
- Diuretics: Taking Vivlodex with diuretics may increase the risk of kidney damage.
Alternatives to Vivlodex
- Celebrex (celecoxib): A selective COX-2 inhibitor used to treat osteoarthritis with a lower risk of gastrointestinal side effects.
- Ibuprofen (Advil, Motrin): A commonly used over-the-counter NSAID for mild to moderate pain relief.
- Naproxen (Aleve): Another over-the-counter NSAID used to relieve pain and inflammation.
- Acetaminophen (Tylenol): A non-NSAID pain reliever that may be used as an alternative for those at risk of NSAID-related side effects.
