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Acular LS

Acular LS, the generic version of ketorolac tromethamine ophthalmic solution, is a nonsteroidal anti-inflammatory drug (NSAID) used in the form of eye drops. It is prescribed to relieve eye pain, burning, and stinging following eye surgery, such as cataract removal. Acular LS works by reducing inflammation in the eye, helping to manage discomfort and promote healing. Its targeted action within the eye makes it an effective option for patients who need relief from post-surgical eye pain and inflammation.



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Frequently Asked Questions

How long does it take for Acular LS to start working?
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Acular LS typically begins to relieve pain and reduce inflammation within a few hours of application, but full effects may take a few days of consistent use.

Can I use Acular LS with other eye medications?
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Yes, but you should wait at least 5 minutes between applying different eye drops to ensure each medication is absorbed properly. Consult your healthcare provider for specific guidance on using multiple eye medications.

What should I do if I miss a dose?
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If you miss a dose, apply it as soon as you remember. If it is almost time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double the dose to make up for the missed one.

Can I wear contact lenses while using Acular LS?
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You should remove your contact lenses before applying Acular LS and wait at least 15 minutes before reinserting them. This helps prevent irritation and ensures the medication is absorbed effectively.

How should I store Acular LS?
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Store Acular LS at room temperature, away from moisture and heat, and keep the bottle tightly closed when not in use. Do not freeze the medication.

What are the signs of an allergic reaction to Acular LS?
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Signs of an allergic reaction include swelling of the face or eyes, difficulty breathing, and severe itching or rash. If you experience any of these symptoms, seek medical attention immediately.

Comprehensive Drug Guide

How Does Acular LS Work?

Acular LS works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. Prostaglandins are chemicals in the body that cause inflammation, pain, and swelling. By blocking their production, Acular LS reduces inflammation and provides relief from pain and discomfort in the eye following surgery. This mechanism helps to manage both the symptoms and underlying causes of postoperative eye inflammation.



Common Dosages

Acular LS is typically available as an ophthalmic solution with a concentration of 0.4%. The medication is supplied in eye drop bottles, and the dosage is usually based on the specific needs of the patient and the severity of the condition being treated.


For adults, the typical dosing of Acular LS involves instilling 1 drop in the affected eye(s) 4 times a day, starting 24 hours after surgery and continuing for 2 weeks. The exact dosing regimen may vary depending on the individual case and the healthcare provider’s recommendations. It is important to follow the prescribed schedule to ensure proper healing and pain management.

Typical Dosing

Who Shouldn't Take Acular LS?

Acular LS should not be used in individuals who have:

  • A known hypersensitivity to ketorolac tromethamine or any other components of the medication.
  • A history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs, as this could increase the risk of severe reactions.
  • Active or suspected infection in the eye, as NSAIDs can mask the signs of infection.

It should also be used with caution in patients with a history of bleeding disorders, as NSAIDs can increase the risk of bleeding.



Advice From The Pharmacist

When using Acular LS, it is important to follow the instructions provided by your healthcare provider. Before applying the drops, wash your hands thoroughly, and avoid touching the tip of the dropper to prevent contamination. If you wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them. If you are using other eye medications, wait at least 5 minutes between different drops to allow each one to be absorbed properly. Report any persistent pain, redness, or irritation to your healthcare provider, as this could indicate a more serious condition.



Side Effects of Acular LS

Common Side Effects

Common side effects of Acular LS include burning or stinging in the eye after application, which usually subsides quickly. Other side effects may include blurred vision, eye redness, or headache. More serious side effects, though rare, can include signs of an allergic reaction (e.g., swelling, difficulty breathing), increased eye pain, or changes in vision. If you experience any of these serious symptoms, seek medical attention immediately.



Risks and Warnings of Acular LS

The major risks associated with Acular LS include the potential for delayed healing, particularly in patients with corneal defects or those using other medications that affect wound healing. NSAIDs like Acular LS can also increase the risk of bleeding in the eye, especially in patients with a history of bleeding disorders or those taking anticoagulant medications. It is important to inform your healthcare provider of your full medical history to mitigate these risks.



Interactions with Acular LS

Common Drug Interactions

Acular LS can interact with other medications, particularly other NSAIDs or medications that affect blood clotting (e.g., aspirin, anticoagulants). Using multiple NSAIDs can increase the risk of side effects, particularly gastrointestinal or bleeding-related issues. It is important to inform your healthcare provider of all medications and supplements you are taking to avoid potential interactions.



Alternatives to Acular LS

Alternative medications for managing postoperative eye pain and inflammation include other NSAID eye drops such as bromfenac or nepafenac, as well as corticosteroid eye drops like prednisolone. The choice of medication will depend on the patient’s specific needs, the severity of the inflammation, and the healthcare provider’s recommendations.