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Flurbiprofen
Flurbiprofen Sodium is a nonsteroidal anti-inflammatory drug (NSAID) commonly used in ophthalmic solutions to reduce inflammation, swelling, and pain in the eye. It is most often prescribed before and after eye surgeries, such as cataract surgery, to prevent inflammation and reduce the risk of complications. Flurbiprofen works by inhibiting the production of prostaglandins, which are chemicals that play a key role in the inflammatory process.
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Frequently Asked Questions
How long should I use Flurbiprofen Sodium after surgery?
Your doctor will determine how long you need to use Flurbiprofen Sodium. In most cases, it is used for a few days to a week following surgery to prevent inflammation.
Can Flurbiprofen Sodium cause blurred vision?
Yes, you may experience temporary blurred vision immediately after applying the drops. This should resolve within a few minutes.
What should I do if I miss a dose?
If you miss a dose, apply it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and return to your regular schedule. Do not double up doses.
Can I use Flurbiprofen Sodium while wearing contact lenses?
It is usually recommended to avoid contact lenses while using Flurbiprofen, particularly after surgery. Consult your doctor for specific instructions.
What should I do if I experience severe eye pain or worsening symptoms?
If you experience severe pain, increased redness, or worsening symptoms, discontinue use and contact your healthcare provider immediately, as this may indicate a more serious condition.
Comprehensive Drug Guide
How Does Flurbiprofen Work?
Flurbiprofen works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins. Prostaglandins are inflammatory mediators that cause pain, swelling, and inflammation. By blocking COX, flurbiprofen reduces inflammation in the eye and helps alleviate pain associated with surgical procedures or inflammatory eye conditions.
What is Flurbiprofen Used For?
Common Dosages
- For preoperative use: 1 drop in the affected eye(s) every 30 minutes starting 2 hours before surgery (a total of 4 drops).
- Postoperative or general inflammation: Follow your healthcare provider's instructions regarding the frequency and duration of treatment.
Typical Dosing
FDA Approved Indications
- Reducing intraoperative miosis (pupil constriction) during eye surgeries, including cataract extraction.
- Postoperative inflammation following eye surgeries.
- Pain and inflammation in ocular conditions requiring anti-inflammatory treatment.
Off-Label Uses
- For offlabel uses:
- Acute gout, dysmenorrhea, postoperative pain: 50 ? 100mg as required, up to four times a day.
Who Shouldn't Take Flurbiprofen?
- Hypersensitivity to flurbiprofen or any components of the ophthalmic solution.
- Asthma or known reactions to NSAIDs, particularly if they have a history of aspirin-exacerbated respiratory disease (AERD).
- Active eye infections, as NSAIDs may delay healing.
Advice From The Pharmacist
- Follow your doctor's instructions for the correct use of Flurbiprofen Sodium before or after surgery.
- Wash your hands before applying the eye drops to avoid contamination.
- Do not touch the tip of the dropper to your eye or any other surface to avoid contamination.
- After applying the drops, close your eyes gently and avoid blinking excessively to allow the medication to absorb.
- Avoid using contact lenses during treatment unless advised by your healthcare provider.
- Do not use other eye medications without consulting your doctor, as certain combinations may affect the efficacy of the treatment.
Side Effects of Flurbiprofen
Common Side Effects
- Temporary stinging or burning sensation in the eye after application
- Redness or irritation in the treated eye
- Blurred vision immediately after application
Uncommon/Severe Side Effects
- Eye pain, increased redness, or worsening inflammation
- Corneal thinning or delayed healing, especially with prolonged use
- Allergic reactions, such as swelling, rash, or difficulty breathing
Risks and Warnings of Flurbiprofen
- Delayed Healing: Long-term use of NSAIDs in the eye may delay corneal healing, particularly in individuals with underlying eye conditions or those undergoing surgery.
- Corneal Effects: Prolonged use of flurbiprofen eye drops can lead to corneal thinning, which may cause discomfort or further eye complications.
- Allergic Reactions: Individuals with known hypersensitivity to NSAIDs should avoid Flurbiprofen Sodium, as it may trigger asthma or allergic reactions.
Interactions with Flurbiprofen
Common Drug Interactions
- Other eye drops: If using other eye medications, wait at least 5 to 10 minutes between applying Flurbiprofen and other drops to prevent interactions and ensure proper absorption.
- Oral NSAIDs: If you are taking oral NSAIDs for other conditions, inform your healthcare provider to avoid excess NSAID exposure.
Alternatives to Flurbiprofen
- Ketorolac (Acular): Another NSAID ophthalmic solution used to treat inflammation and pain after eye surgeries.
- Diclofenac Sodium (Voltaren Ophthalmic): A similar NSAID eye drop used for treating postoperative inflammation.
- Prednisolone Acetate: A corticosteroid ophthalmic solution used to reduce severe inflammation in the eye.
- Bromfenac (Prolensa): Another NSAID used to reduce inflammation after cataract surgery.
