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Elyxyb
Elyxyb (generic name: celecoxib oral solution) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat acute migraine attacks with or without aura. It is specifically formulated as a liquid solution to provide rapid relief from migraine symptoms, such as headache, nausea, and sensitivity to light or sound. Elyxyb belongs to the class of COX-2 inhibitors, which are designed to reduce pain and inflammation with fewer gastrointestinal side effects than traditional NSAIDs.
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Frequently Asked Questions
How fast does Elyxyb work?
Elyxyb begins working within 30 minutes to relieve migraine symptoms, thanks to its liquid formulation that allows for faster absorption.
Can I take Elyxyb with other migraine medications?
Consult your doctor before combining Elyxyb with other migraine treatments, especially triptans or other NSAIDs, as this could increase the risk of side effects.
How often can I use Elyxyb?
You should not take more than one dose of Elyxyb in a 24-hour period. If migraine symptoms persist, consult your healthcare provider.
Can Elyxyb be used to prevent migraines?
No, Elyxyb is not intended for migraine prevention. It is used to treat acute attacks when they occur.
Is Elyxyb safe during pregnancy?
Elyxyb should be avoided during pregnancy, particularly in the third trimester, due to the risk of harm to the unborn baby.
Comprehensive Drug Guide
How Does Elyxyb Work?
Elyxyb works by inhibiting the cyclooxygenase-2 (COX-2) enzyme, which plays a key role in the production of prostaglandins, chemicals that cause inflammation and pain. By blocking COX-2, Elyxyb helps reduce migraine pain and associated symptoms.
Common Dosages
- 25 mg/mL in 4.8 mL single-use bottles, delivering 120 mg of celecoxib per dose.
Typical Dosing
- The typical dosing for Elyxyb is a single 120 mg dose (one bottle) taken orally at the onset of migraine symptoms. The dose should not be repeated within 24 hours.
Typical Dosing
FDA Approved Indications
- Migraine attacks with or without aura in adults
Who Shouldn't Take Elyxyb?
- Allergic reactions to NSAIDs or aspirin
- Severe liver or kidney disease
- Coronary artery bypass graft (CABG) surgery
- History of asthma or hives with NSAID use
Advice From The Pharmacist
- Take Elyxyb at the first sign of a migraine for the best results. Shake the bottle well before use.
- Elyxyb is not for the preventive treatment of migraines, so use it only for acute attacks.
- If you have a history of heart disease or gastrointestinal issues, discuss these with your doctor before using Elyxyb, as NSAIDs can increase the risk of cardiovascular events or stomach bleeding.
- Do not use Elyxyb if you are pregnant, especially during the third trimester.
Side Effects of Elyxyb
Common Side Effects
- Nausea
- Dizziness
- Diarrhea
- Indigestion
Uncommon/Severe Side Effects
- Heart attack
- Stroke
- Gastrointestinal bleeding
- Kidney damage
Risks and Warnings of Elyxyb
- Cardiovascular Risk: NSAIDs like Elyxyb can increase the risk of serious cardiovascular events like heart attack or stroke, especially in people with pre-existing heart conditions or those who use it long-term.
- Gastrointestinal Risk: Elyxyb can cause stomach ulcers or bleeding, particularly in older adults or those with a history of gastrointestinal problems.
- Kidney Function: Prolonged use of NSAIDs may impair kidney function, especially in people with pre-existing kidney disease.
Interactions with Elyxyb
Common Drug Interactions
- Anticoagulants: Medications like warfarin can increase the risk of bleeding when taken with Elyxyb.
- Aspirin or other NSAIDs: Combining Elyxyb with other NSAIDs increases the risk of stomach ulcers or kidney damage.
- Blood pressure medications: NSAIDs can reduce the effectiveness of antihypertensive medications.
Alternatives to Elyxyb
- Maxalt (rizatriptan): A migraine-specific medication in the triptan class, used for acute migraine relief.
- Imitrex (sumatriptan): A triptan used for migraine attacks, available in tablet, nasal spray, and injection forms.
- Cambia (diclofenac potassium): Another NSAID formulated for acute migraine treatment.
