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Xrylix

Xrylix (generic name: lidocaine topical) is a topical anesthetic used to relieve pain and discomfort associated with conditions such as minor burns, sunburns, insect bites, minor cuts, scrapes, and skin irritations. Lidocaine, the active ingredient, works by numbing the area where it is applied, providing temporary relief from pain and itching.

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Frequently Asked Questions

How quickly does Xrylix start working?
Open FAQClose FAQ

Xrylix typically starts to numb the area within a few minutes of application, providing temporary relief from pain or itching.

Can I use Xrylix on an open wound?
Open FAQClose FAQ

No, Xrylix should not be used on open wounds, broken skin, or infected areas, as this can increase the risk of systemic absorption and potential side effects.

What should I do if I accidentally apply too much Xrylix?
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If you apply too much or experience symptoms of lidocaine toxicity (such as dizziness, confusion, or irregular heartbeat), wash the area thoroughly with soap and water and seek medical attention.

Can I use Xrylix for sunburn relief?
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Yes, Xrylix can be used to relieve pain and itching associated with sunburn, but avoid using it on severely blistered or broken skin.

Is Xrylix safe for children?
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Xrylix can be used in children, but caution should be exercised to avoid applying it to large areas or using it for prolonged periods. Consult a healthcare provider for guidance on safe use in children.

Comprehensive Drug Guide

How Does Xrylix Work?

Lidocaine works by blocking sodium channels in the nerve cells, which prevents the transmission of pain signals to the brain. This results in temporary numbing of the affected area, providing relief from pain and itching.

Common Dosages

  • 4% lidocaine topical cream, gel, or ointment

Typical Dosing

  • Apply a thin layer of Xrylix to the affected area up to 3 to 4 times daily. Be sure to rub the product in gently until it is fully absorbed.

Typical Dosing

FDA Approved Indications

  • Temporary relief of pain and itching due to minor skin irritations, such as burns, insect bites, sunburns, cuts, scrapes, and minor rashes.

Who Shouldn't Take Xrylix?

  • Known hypersensitivity to lidocaine or other topical anesthetics.
  • Severe liver disease, as this can affect the metabolism of lidocaine.

Advice From The Pharmacist

  • Avoid applying Xrylix to broken or infected skin, as this can increase absorption and the risk of side effects.
  • Wash your hands before and after applying Xrylix unless treating your hands.
  • Do not cover the treated area with a bandage or occlusive dressing unless instructed by your healthcare provider, as this may increase absorption and the risk of side effects.
  • Use caution in children, and avoid large surface areas or prolonged use.

Side Effects of Xrylix

Common Side Effects

  • Temporary redness or irritation at the application site
  • Mild burning or itching

Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, swelling, difficulty breathing)
  • Methemoglobinemia (a rare condition affecting oxygen transport in the blood, more common with high doses or prolonged use)

Risks and Warnings of Xrylix

  • Overuse and Absorption: Over-application or use on large areas of the skin can lead to increased absorption of lidocaine and result in systemic side effects such as dizziness, confusion, and irregular heartbeats. Follow dosing instructions carefully.
  • Allergic Reactions: If signs of an allergic reaction occur, such as a rash, itching, or swelling, discontinue use and seek medical attention immediately.

Interactions with Xrylix

Common Drug Interactions

  • Other topical anesthetics: Using Xrylix with other lidocaine-containing products or anesthetics may increase the risk of systemic toxicity.
  • Class I antiarrhythmics: Lidocaine is chemically similar to certain antiarrhythmics (e.g., mexiletine) and should be used cautiously in combination with these medications.

Alternatives to Xrylix

  • Benzocaine (Solarcaine): Another topical anesthetic used to relieve pain and itching associated with minor skin irritations.
  • Hydrocortisone: A mild topical steroid used to reduce itching and inflammation associated with minor skin irritations.
  • Calamine lotion: A soothing lotion used for itching and discomfort associated with rashes, insect bites, and other skin irritations.