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Lidocaine

Lidocaine is a local anesthetic that numbs certain parts of the body. It's widely used in minor surgeries or dental procedures. It can also help reduce acute pain associated with conditions such as post-herpetic neuralgia.

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Frequently Asked Questions

What if I forget an application of Lidocaine?
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If it's close to your next application time, just carry on with the upcoming one. If not, apply it as soon as you remember. Do not double up on the dose.

Can Lidocaine make me sleepy?
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Tiredness is a potential side effect if injected, but not everyone experiences it. We advise against driving or indulging in any hazardous activities if you feel drowsy or dizzy.

Is it safe to use Lidocaine while I'm pregnant?
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While Lidocaine is generally considered safe during pregnancy, it's always best to check with your doctor before using any medications while pregnant.

Can Lidocaine make me feel jittery or restless?
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Rare side effects can include feelings of unease, dizziness, or anxiety. If you experience these symptoms or if they worsen, contact your doctor.

Is it okay for me to enjoy a glass of wine while using Lidocaine?
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There's no specific warning against alcohol, but it could potentially amplify certain side effects like drowsiness. Always confirm with your doctor or pharmacist.

Comprehensive Drug Guide

How Does Lidocaine Work?

Lidocaine is a local anesthetic that works by blocking the voltage-gated sodium channels in the nerve cells. This inhibits the propagation of nerve impulses and hence, the sensation of pain.

What is Lidocaine Used For?

Lidocaine is approved for Anesthesia of the oropharynx, postherpetic neuralgia, and topical local anesthetic to the skin.

Common Dosages

  • Topical: Available in creams, ointments, patches, and gels ranging from 4% to 5%
  • Injectable solution: 0.5%, 1%, 1.5%, 2%, and 4%


Typical Dosing

FDA Approved Indications

The dosing for Lidocaine depends on the type of procedure and the age, weight, and overall health of the patient. The doctor will decide the amount and concentration.


Who Shouldn't Take Lidocaine?

  • Allergies to Lidocaine or any other anesthetics of the amide type
  • Those with severe liver disease
  • Those with certain heart conditions
  • Those with a history of malignant hyperthermia


Advice From The Pharmacist

  • Lidocaine is only meant for use on the skin or certain body areas. Do not use in the mouth, nose, or ears, unless directed by a doctor.
  • Don’t wrap an area where you’ve applied lidocaine in heat or tight bandages unless told to do so by a doctor.
  • Don’t get this medication in your eyes. If this does happen, rinse with plenty of water.
  • Always wash your hands after applying this medication.
  • If you’re using this medication long-term, you may need regular health checkups.
  • Discontinue use and get medical help if you experience severe side effects such as mood changes, drowsiness, seizures, and slow or irregular heartbeat.


Side Effects of Lidocaine

Common Side Effects

  • Your skin may appear red, and itchy, or develop a rash at the application site.
  • You may also feel a stinging or burning sensation when the medicine is applied.


Uncommon/Severe Side Effects

In rare cases, you may experience severe allergic reactions such as swelling, severe rash, itching, or trouble breathing.

Risks and Warnings of Lidocaine

  • Allergic Reactions: After applying Lidocaine, if you experience severe itching, rashes, hives, difficulty in breathing or swallowing, or swelling of the face, throat, or tongue, immediately stop using it and seek medical help.
  • Heart problems: Lidocaine's action on heart rhythm means those with heart conditions need to be careful when using it. Always inform your health provider about any pre-existing heart conditions.
  • Liver Disease: Lidocaine is metabolized in the liver. Hence, people with severe liver impairment need to use this medication with caution. Consult your doctor for appropriate dosage guidance.
  • Overdose Risk: Too much lidocaine can get into your bloodstream, leading to toxic effects. Symptoms of overdose include drowsiness, confusion, hallucinations, numbness around the mouth, ringing in ears, or tremors.
  • Drug Interactions: Lidocaine can interact with other drugs leading to side effects. Always inform your health provider about any medications you are currently taking.
  • Pregnancy and breastfeeding: Although no adequate studies have been conducted, lidocaine should only be used during pregnancy and breastfeeding if the benefits outweigh the risks to the fetus or baby.
  • CNS Reactions: High doses or unintentional ingestion may lead to CNS effects like excitement, nervousness, restlessness, dizziness, blurred vision, tremors, or seizures. In severe cases, it can lead to coma and respiratory arrest.


Interactions with Lidocaine

Common Drug Interactions

  • Antiarrhythmics (like amiodarone, mexiletine)
  • Beta-blockers like propranolol
  • Cimetidine
  • Other local anesthetics or similar medications


Alternatives to Lidocaine

  • Prilocaine
  • Benzocaine
  • Tetracaine
  • Procaine