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Iclofenac CP
Iclofenac CP (diclofenac) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is commonly prescribed for various conditions, including osteoarthritis, rheumatoid arthritis, and acute pain associated with injuries or surgeries. Iclofenac CP works by inhibiting the production of prostaglandins, substances in the body that mediate inflammation and pain.
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Frequently Asked Questions
How long does it take for Iclofenac CP to start working?
Patients may begin to feel relief within a few hours, but it may take several days for the full benefits to be realized for conditions like arthritis.
Can I take Iclofenac CP with other medications?
Always consult your healthcare provider before combining Iclofenac CP with other medications, especially other NSAIDs, blood thinners, or medications that affect kidney function.
What should I do if I miss a dose of Iclofenac CP?
If you miss a dose, take it as soon as you remember. If it's close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
Is it safe to use Iclofenac CP during pregnancy?
Iclofenac CP should be used during pregnancy only if clearly needed, and the risks and benefits should be discussed with a healthcare provider.
Can Iclofenac CP cause weight gain?
Weight gain can occur as a side effect due to fluid retention, so patients should monitor their weight and discuss any concerns with their healthcare provider.
Comprehensive Drug Guide
How Does Iclofenac CP Work?
Iclofenac CP works by inhibiting the activity of cyclooxygenase (COX) enzymes, which are essential for the synthesis of prostaglandins. By blocking these enzymes, Iclofenac reduces the levels of prostaglandins, leading to decreased inflammation, alleviation of pain, and reduced fever.
Common Dosages
- Tablets: Common dosages include 50 mg, 75 mg, and 100 mg.
Typical Dosing
- The usual starting dose for adults may range from 75 to 150 mg per day, divided into two or three doses based on the condition being treated.
- For acute pain, higher doses may be required initially, followed by a tapering dose as symptoms improve.
Typical Dosing
FDA Approved Indications
- Osteoarthritis
- Rheumatoid arthritis
- Acute pain
- Ankylosing spondylitis
Who Shouldn't Take Iclofenac CP?
- Known hypersensitivity to diclofenac or any components of the formulation
- Active gastrointestinal bleeding or ulceration
- Severe renal impairment
- History of asthma or allergic reactions to NSAIDs
Advice From The Pharmacist
- Iclofenac CP should be taken with food or milk to minimize gastrointestinal irritation.
- Patients should be monitored for signs of gastrointestinal bleeding, such as black or tarry stools, and should report any severe abdominal pain.
- Regular follow-up appointments are recommended to monitor the effectiveness and any potential side effects.
Side Effects of Iclofenac CP
Common Side Effects
- Gastrointestinal upset (nausea, vomiting, diarrhea)
- Headache
- Dizziness
- Stomach pain
Uncommon/Severe Side Effects
- Severe allergic reactions (anaphylaxis)
- Gastrointestinal bleeding or ulceration
- Increased blood pressure
Risks and Warnings of Iclofenac CP
- Gastrointestinal Risks: Iclofenac CP can cause serious gastrointestinal issues, including bleeding, ulceration, and perforation.
- Cardiovascular Risks: Long-term use may increase the risk of heart attack or stroke, particularly in individuals with existing heart disease.
- Renal Effects: Monitor kidney function in patients taking Iclofenac CP, especially those with pre-existing kidney issues.
Interactions with Iclofenac CP
Common Drug Interactions
- Anticoagulants: Iclofenac may increase the risk of bleeding when taken with blood thinners like warfarin.
- Other NSAIDs: Using multiple NSAIDs concurrently can increase the risk of gastrointestinal side effects.
- Diuretics and ACE Inhibitors: Iclofenac may reduce the effectiveness of these medications.
Alternatives to Iclofenac CP
- Naproxen: Another NSAID commonly used for pain and inflammation.
- Ibuprofen: A widely used NSAID for various inflammatory conditions.
- Celecoxib (Celebrex): A COX-2 selective inhibitor that may have a lower risk of gastrointestinal side effects.
