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Diclotrex
Diclotrex is an NSAID (nonsteroidal antiinflammatory drug) primarily used for pain relief, inflammation reduction, and fever reduction. It is common to use Diclotrex for conditions like arthritis and menstrual pain. Some common side effects include nausea, vomiting, upset stomach, and drowsiness, but these are mostly manageable.
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Frequently Asked Questions
Can I take Diclotrex if I have kidney disease?
If you have kidney disease, consult your doctor before starting Diclotrex. It may impact renal function adversely.
Does Diclotrex make you sleepy?
Yes, drowsiness can be a side effect. If this persists or worsens, inform your doctor.
I missed a dose of Diclotrex, what should I do?
Take it as soon as you remember. If it's near the time of your next dose, skip the missed dose and resume your usual dosing schedule. Don't double the dose.
Comprehensive Drug Guide
How Does Diclotrex Work?
Diclotrex is a type of NSAID that inhibits the enzymes (COX1 and COX2) responsible for producing prostaglandins, which are mediators of inflammation and pain in the body.
What is Diclotrex Used For?
FDA indications: Diclotrex is used for relieving pain, reducing inflammation, and lowering fever. It is quite effective in managing arthritis and menstrual cramps.
Offlabel uses: Some doctors may prescribe Diclotrex for gout attacks or migraines.
Common Dosages
Tablets: 25mg, 50mg, 75mg
Oral solution: 1.5mg/mL, 10mg/mL (liquid)
Topical gel: 1%, 3%
Typical Dosing
FDA Approved Indications
- The dosing of Diclotrex depends on the condition, its severity, and the patient's response to treatment.
- Generally, for arthritis, the recommended dose is 100150mg per day in divided doses.
- For menstrual pain, it's typically 50 mg every 8 hours.
- Always follow your doctor's prescription instructions.
Who Shouldn't Take Diclotrex?
- Patients with known hypersensitivity to Diclotrex or any component of the formulation.
- Patients who have experienced asthma, urticaria, or allergic reactions after taking aspirin or other NSAIDs.
- Patients with the syndrome of nasal polyps, angioedema, and bronchospastic reactivity to aspirin or other NSAIDs.
- Patients with a history of stomach ulcers or gastrointestinal bleeding.
- Pregnant women, especially those in their third trimester.
- Patients who have recently undergone or are about to undergo heart surgery.
Advice From The Pharmacist
- Consuming food or milk before ingestion can prevent stomach upset.
- Avoid lying down for at least 10 minutes after taking Diclotrex.
- The drug may cause dizziness; refrain from activities like driving until you're sure of how Diclotrex affects you.
- Report signs of stomach bleeding to your doctor immediately.
Side Effects of Diclotrex
Common Side Effects
- Upset stomach
- Diarrhea, constipation
- Headache, dizziness
- Mild itching or skin rash
Uncommon/Severe Side Effects
- Severe side effects:
- Signs of stomach bleeding
- Liver disease symptoms
- Kidney problems
- Signs of heart failure
Risks and Warnings of Diclotrex
- Diclotrex can cause severe stomach bleeding, kidney issues, and an increased risk of heart attack or stroke.
- Avoid consuming alcohol as it can increase your stomach bleeding risk.
- Inform your doctor if you have asthma, high blood pressure, diabetes, liver, or kidney diseases.
Interactions with Diclotrex
Common Drug Interactions
- Aspirin
- Anticoagulants
- ACE inhibitors
- Diuretics
Alternatives to Diclotrex
- Ibuprofen
- Naproxen
- Meloxicam
- Celecoxib
- Indomethacin