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Acuvail
Acuvail (ketorolac tromethamine) is a nonsteroidal anti-inflammatory drug (NSAID) indicated for the temporary relief of ocular pain and inflammation following cataract surgery. It is delivered in a sterile, preservative-free eye drop formulation, designed to provide targeted relief directly to the affected area. By reducing inflammation and providing analgesia, Acuvail aids in improving patient comfort during the postoperative recovery period.
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Frequently Asked Questions
How long does it take for Acuvail to work?
Acuvail typically begins to relieve pain and inflammation within a few hours of application, but individual response times may vary.
Can I use Acuvail with contact lenses?
It is recommended to remove contact lenses before applying Acuvail and wait at least 15 minutes before reinserting them to avoid potential irritation.
What should I do if I miss a dose of Acuvail?
If you miss a dose, apply it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule.
Is Acuvail safe for long-term use?
Acuvail is intended for short-term use following cataract surgery. Long-term use should be monitored by a healthcare provider due to potential side effects.
Can I take other medications while using Acuvail?
Always inform your healthcare provider about all medications you are taking, including over-the-counter drugs, to avoid potential interactions.
Comprehensive Drug Guide
How Does Acuvail Work?
Acuvail works by inhibiting the cyclooxygenase (COX) enzymes, which are responsible for the production of prostaglandins, compounds that mediate inflammation, pain, and fever. By reducing prostaglandin synthesis in the ocular tissues, Acuvail decreases inflammation and alleviates pain associated with surgical procedures.
Common Dosages
- Ophthalmic solution: 0.45% ketorolac tromethamine
Typical Dosing
- The typical dosing for Acuvail is one drop instilled into the affected eye(s) twice daily, starting 24 hours before surgery and continuing for up to 2 weeks postoperatively, as directed by the healthcare provider.
Typical Dosing
FDA Approved Indications
- Ocular pain and inflammation following cataract surgery
Who Shouldn't Take Acuvail?
- Known hypersensitivity to ketorolac or any components of the formulation
- Active or history of recurrent peptic ulcer disease or gastrointestinal bleeding
- Severe renal impairment
Advice From The Pharmacist
- Use Acuvail exactly as prescribed by your healthcare provider. Avoid touching the dropper tip to any surface, including the eye, to prevent contamination.
- Allow the eye drops to reach room temperature before use if they have been stored in the refrigerator.
- Wait at least 5 minutes between instilling Acuvail and any other eye medications to avoid dilution or interaction.
- If you experience persistent eye irritation, redness, or visual disturbances, contact your healthcare provider.
Side Effects of Acuvail
Common Side Effects
- Burning or stinging upon application
- Redness of the eye
- Dry eyes
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, itching, swelling, or difficulty breathing)
- Corneal edema or other serious ocular conditions
Risks and Warnings of Acuvail
- Corneal Effects: Prolonged use of NSAIDs in the eye may lead to corneal complications. Patients should be monitored for signs of corneal damage.
- Systemic Absorption: Although Acuvail is applied topically, systemic absorption can occur. Caution should be exercised in patients with a history of cardiovascular disease, renal impairment, or gastrointestinal disorders.
- Allergic Reactions: Patients should be aware of the potential for allergic reactions and report any unusual symptoms to their healthcare provider.
Interactions with Acuvail
Common Drug Interactions
- Other Ocular Medications: When using multiple ophthalmic medications, allow at least 5 minutes between applications to prevent interactions.
- NSAIDs: Patients should avoid using other NSAIDs concurrently to reduce the risk of adverse effects.
Alternatives to Acuvail
- Other NSAID eye drops: Such as diclofenac or flurbiprofen, may be used for similar indications.
- Corticosteroid eye drops: These may be considered for inflammation management in specific cases.
- Topical analgesics: Other formulations for ocular pain relief may be available, depending on the individual patient's needs.
