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Diclozor
Diclozor (generic name: diclofenac sodium) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. It works by reducing substances in the body that cause inflammation and pain. Diclozor is commonly prescribed to help manage chronic pain and inflammation related to musculoskeletal conditions and post-operative pain.
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Frequently Asked Questions
Can Diclozor be taken long-term for arthritis?
Yes, Diclozor can be used for long-term management of arthritis, but it should be monitored regularly for side effects such as gastrointestinal bleeding and kidney function issues.
Can I take Diclozor with other pain relievers?
Avoid using other NSAIDs like ibuprofen or aspirin while taking Diclozor, but acetaminophen (Tylenol) may be used for additional pain relief under your doctor’s guidance.
Does Diclozor cause stomach ulcers?
Yes, Diclozor, like other NSAIDs, can increase the risk of stomach ulcers and bleeding, especially with long-term use. Taking it with food can reduce this risk.
How long does it take for Diclozor to work?
Diclozor typically begins to relieve pain within 30-60 minutes of taking a dose, but its anti-inflammatory effects may take several days to become fully apparent.
Can Diclozor cause sun sensitivity?
Yes, Diclozor can make your skin more sensitive to sunlight, particularly in topical forms. Use sunscreen and avoid excessive sun exposure while using this medication.
Comprehensive Drug Guide
How Does Diclozor Work?
Diclozor works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for producing prostaglandins, the chemicals in the body that promote inflammation, pain, and fever. By blocking this enzyme, Diclozor helps reduce inflammation and alleviate pain.
Common Dosages
- Tablets: 25 mg, 50 mg, 75 mg, and extended-release 100 mg
- Topical gel: 1% or 3% strength
- Ophthalmic solution: 0.1% for post-surgical inflammation
Typical Dosing
- For osteoarthritis or rheumatoid arthritis: The usual dose is 50 mg taken orally two to three times daily or 100 mg extended-release once daily.
- For acute pain: 50 mg taken every 6-8 hours as needed, but not exceeding 150 mg per day.
- Topical formulations: Apply 2-4 grams of gel to the affected area up to four times daily.
Typical Dosing
FDA Approved Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute pain
- Dysmenorrhea (painful menstruation)
Who Shouldn't Take Diclozor?
- Hypersensitivity to diclofenac or other NSAIDs
- Active gastrointestinal bleeding or ulcers
- Severe liver or kidney impairment
- History of asthma, hives, or other allergic reactions to aspirin or NSAIDs
Advice From The Pharmacist
- Take Diclozor with food or milk to reduce the risk of stomach upset or gastric ulcers.
- Avoid using other NSAIDs (like ibuprofen or aspirin) while taking Diclozor to reduce the risk of gastrointestinal side effects.
- If using the topical gel, apply only to clean, dry skin and avoid applying to open wounds or infected areas.
- Diclozor can increase sensitivity to sunlight, so use sunscreen and protective clothing when outdoors.
Side Effects of Diclozor
Common Side Effects
- Nausea
- Heartburn
- Diarrhea
- Dizziness
Uncommon/Severe Side Effects
- Gastrointestinal bleeding
- Ulcers
- Kidney damage
- Liver toxicity
Risks and Warnings of Diclozor
- Cardiovascular Risk: NSAIDs like Diclozor may increase the risk of heart attack or stroke, especially with long-term use or in individuals with existing cardiovascular conditions.
- Gastrointestinal Risk: Diclozor can cause stomach ulcers, bleeding, and perforation, which can occur without warning, especially in older adults.
- Liver and Kidney Damage: Prolonged use of Diclozor may cause liver or kidney damage, requiring regular monitoring of liver and kidney function.
Interactions with Diclozor
Common Drug Interactions
- Anticoagulants (like warfarin): Increases the risk of bleeding.
- Diuretics: Can reduce the effectiveness of diuretics and worsen kidney function.
- Corticosteroids: May increase the risk of gastrointestinal side effects such as ulcers or bleeding.
- Antihypertensives (like ACE inhibitors): NSAIDs can reduce the effectiveness of these medications.
Alternatives to Diclozor
- Ibuprofen: Another NSAID commonly used for pain and inflammation.
- Naproxen: Another NSAID used for pain relief and inflammation control.
- Celecoxib (Celebrex): A COX-2 inhibitor NSAID that has a lower risk of gastrointestinal side effects.
- Meloxicam: A prescription NSAID that is often used for chronic inflammatory conditions.
