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Mefenamic Acid
Mefenamic acid is a type of medication known as a nonsteroidal antiinflammatory drug (NSAID). It's typically used for shortterm treatment of mild to moderate pain, including menstrual pain. Some common side effects include nausea, vomiting, stomach pain, drowsiness, and diarrhea, but your doctor will usually weigh the benefits against these potential issues.
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Frequently Asked Questions
Can I just stop taking Mefenamic Acid once my symptoms are gone?
If you're taking mefenamic acid for a shortterm pain issue, you likely can stop once your symptoms have resolved. Always talk to your doctor before stopping or changing the dose of any medication.?
Can I take Mefenamic Acid if I have high blood pressure?
It ??s possible, but mefenamic acid may cause a rise in blood pressure. Your doctor may want to monitor your blood pressure closely while you are taking mefenamic acid.
Does Mefenamic Acid make you drowsy?
Drowsiness is a common side effect of mefenamic acid. If you notice this, avoid driving or other activities that require alertness until you know how the medication affects you.
I missed a dose of Mefenamic Acid, what should I do?
If it's near the time for your next dose, skip the missed one. If there's still plenty of time before your next dose, take the missed dose as soon as you remember. Never double up on doses to make up for a missed one!
Comprehensive Drug Guide
How Does Mefenamic Acid Work?
Mefenamic acid works by inhibiting the action of an enzyme in the body called cyclooxygenase (COX), which is involved in the production of prostaglandins that trigger pain and inflammation.
What is Mefenamic Acid Used For?
FDA indications: Mefenamic Acid is used for shortterm treatment of acute pain, including menstrual pain.
Offlabel uses: There are currently no widely recognized offlabel uses.
Common Dosages
Capsules: 250mg
Typical Dosing
FDA Approved Indications
- Acute pain and Dysmenorrhea: 500mg initially, followed by 250mg every 6 hours as needed, typically not to exceed one week
Who Shouldn't Take Mefenamic Acid?
- Those who've had an allergic reaction to mefenamic acid or other NSAIDs.
- Individuals who have a history of stomach ulcers or bleeding problems.
- Patients with severe kidney disease.
- Patients who are about to undergo heart surgery.
- People with asthma, especially those who have suffered from asthma attacks triggered by NSAIDs.
- Pregnant women in their third trimester, as it may harm the baby.
Advice From The Pharmacist
- Take mefenamic acid with or after a meal or snack to prevent stomach upset.
- Do not lie down for at least 10 minutes after taking this medicine.
- Avoid drinking alcohol while taking mefenamic acid, as it can increase your risk of stomach bleeding.
- It may take up to two weeks to feel the full benefits of this medicine.
- Mefenamic acid should only be used for shortterm treatment.
- If your symptoms do not improve or if they become worse, consult your healthcare professional.
Side Effects of Mefenamic Acid
Common Side Effects
- You might get a stomach ache, indigestion, or heartburn.
- You might develop a rash or itching.
- You might feel headaches or dizziness.
Uncommon/Severe Side Effects
- Uncommon side effects:
- You might develop a buzzing or ringing in your ears.
- You might feel sleepy or unusually tired.
- You might have difficulty breathing, chest pain, or palpitations.
- Rare side effects:
- You might develop symptoms of jaundice such as yellowing skin/eyes.
- You might get bloody or cloudy urine.
- You might notice unusual weight gain and swelling in the ankles or feet.
- Severe side effects:
- Signs of a serious allergic reaction like a rash, itching/swelling in the face/tongue/throat, severe dizziness, breathing trouble, or unexplained fever, this is serious, and immediate medical attention is needed.
Risks and Warnings of Mefenamic Acid
- Remember that mefenamic acid can increase your risk of fatal heart attack or stroke when used in high doses or for long periods.
- Mefenamic acid may also cause stomach or intestinal bleeding, which could be fatal.
- If you're pregnant, the use of mefenamic acid in the third trimester should be avoided as it may harm the baby.
- Individuals with asthma, especially those who've suffered asthma attacks triggered by NSAIDs, should avoid mefenamic acid.
Interactions with Mefenamic Acid
Common Drug Interactions
- Aspirin, other NSAIDs
- Lithium
- Blood thinners (such as warfarin)
- High blood pressure medications
- Diuretics (like furosemide)
Alternatives to Mefenamic Acid
- Ibuprofen
- Naproxen
- Diclofenac
- Celecoxib
- Piroxicam
- Indomethacin
