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Oxaprozin
Oxaprozin is a type of oral medication classified as a nonsteroidal antiinflammatory drug (NSAID). It's effective in relieving pain, reducing inflammation, and lowering high body temperature. Common conditions including osteoarthritis, rheumatoid arthritis, and juvenile idiopathic arthritis may be managed with this medication.
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Frequently Asked Questions
Can I just stop taking Oxaprozin because I feel better?
No. Always consult your physician before stopping medication. Suddenly stopping can lead to withdrawal symptoms.
Can I take Oxaprozin with alcohol?
No! Alcohol may increase the risk of severe stomach bleeding.
Does Oxaprozin cause weight gain?
While weight changes are possible though rare as side effects, prompt help should be taken from a doctor.
What if I miss a dose of Oxaprozin?
If you miss a dose, take it as soon as you can. If it's almost time for the next dose, skip it and continue with your regular schedule.
Comprehensive Drug Guide
How Does Oxaprozin Work?
Oxaprozin is a medicine that helps reduce pain and swelling in your body. It belongs to a group of drugs called nonsteroidal anti-inflammatory drugs, or NSAIDs for short.
When you have an injury or a condition like arthritis, your body makes chemicals called prostaglandins. These chemicals cause inflammation, which leads to pain, redness, and swelling. Oxaprozin works by blocking the production of prostaglandins. It does this by stopping an enzyme called cyclooxygenase from making them.
Oxaprozin helps decrease inflammation by reducing the amount of prostaglandins. This means you feel less pain and swelling, making it easier to move around and do your daily activities.
What is Oxaprozin Used For?
FDA indications: Oxaprozin is primarily used to alleviate pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and juvenile arthritis.
Offlabel uses: It can also be used offlabel to manage pain for short periods, such as with dental pain or other minor injuries.
Common Dosages
Offlabel uses: It's also been used for the offlabel treatment of malaria prevention.
Typical Dosing
FDA Approved Indications
- Osteoarthritis: 1200mg once daily.
- Rheumatoid arthritis: 1200mg once daily.
- Juvenile idiopathic arthritis: Based on weight, usually 20 to 30mg/kg daily.
Off-Label Uses
- For offlabel uses: Shortterm pain management: 600 to 1200mg once daily.
Who Shouldn't Take Oxaprozin?
- People allergic to Oxaprozin or other NSAIDs?
- People with a history of heart attack or stroke?
- Those with a history of stomach ulcers or bleeding, or have significant risk factors for cardiovascular disease
- Pregnant women, particularly in the third trimester?
- People with severe kidney or liver disease?
- Those with asthma, who also suffer from nasal polyps and severe chronic urticaria
Advice From The Pharmacist
- Take Oxaprozin with a meal or right after, to lower the chances of an upset stomach.
- Limit alcohol and stop smoking while on this medication, as it increases the risk of stomach bleeding.
- Regular blood tests may be required to monitor your progress and check for side effects.
- Do not use Oxaprozin just before or after heart bypass surgery.
- Let your doctor know if you are planning to get pregnant, its use isn't recommended during pregnancy.
- Avoid sunlight exposure and tanning beds, as Oxaprozin can make your skin more sensitive to sunlight.
Side Effects of Oxaprozin
Common Side Effects
- You might experience an upset stomach, nausea, heartburn, dizziness, or drowsiness.
Uncommon/Severe Side Effects
- Uncommon side effects: Some people experience hearing changes such as ringing in the ears, mental/mood changes, and difficult/painful swallowing.
- Rare side effects: In rare cases, you could have symptoms of heart failure such as swelling ankles or feet, unusual tiredness, and unusual or sudden weight gain.
- Severe side effects Get medical help right away if you experience any serious side effects such as chest or jaw pain, signs of kidney problems, unexplained stiff neck, or unexplained seizures.?
Risks and Warnings of Oxaprozin
- Using Oxaprozin for a long time or in high doses might increase the risk of heart attack or stroke.
- This medication may cause ulcers or holes in the stomach.
- Oxaprozin might cause kidney problems or worsen existing ones.
- Seek medical attention right away for symptoms such as rash, neck stiffness, severe headache, fever, and vomiting.
- Do not take Oxaprozin if you are allergic to aspirin or other NSAIDs.
Interactions with Oxaprozin
Common Drug Interactions
- Diuretics
- Anticoagulants
- Antiplatelet drugs
- ACE inhibitors
- SSRIs
- Other NSAIDs
Alternatives to Oxaprozin
Ibuprofen
Naproxen
Diclofenac
Meloxicam
Celecoxib
Indomethacin
Piroxicam
Etodolac
Sulindac
Ketoprofen
