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Diclofono
Diclofono (diclofenac) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, inflammation, and swelling caused by conditions such as arthritis, muscle injuries, and menstrual cramps. It works by reducing the production of substances in the body that cause inflammation and pain. Diclofono is commonly prescribed for short-term and long-term management of various pain conditions.
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Frequently Asked Questions
How long does it take for Diclofono to start working?
You may start to feel relief from pain and inflammation within 30 minutes to 1 hour of taking Diclofono.
Can Diclofono be used for long-term treatment?
Diclofono can be used for long-term conditions like arthritis, but regular monitoring by your healthcare provider is necessary to prevent long-term side effects, such as gastrointestinal bleeding or kidney damage.
Can I take Diclofono with other pain relievers?
It is generally safe to combine Diclofono with acetaminophen, but you should avoid taking it with other NSAIDs like ibuprofen or naproxen, as this increases the risk of side effects. Always check with your healthcare provider.
What should I do if I miss a dose of Diclofono?
Take the missed dose as soon as you remember, unless it’s almost time for your next dose. Do not double the dose to make up for a missed one.
Is Diclofono safe during pregnancy?
Diclofono is not recommended during pregnancy, especially in the third trimester, as it may cause harm to the developing baby and complications during delivery. Always consult your doctor before using any medication during pregnancy.
Comprehensive Drug Guide
How Does Diclofono Work?
Diclofono works by inhibiting the enzyme cyclooxygenase (COX), which is responsible for the production of prostaglandins, chemicals that cause pain and inflammation in the body. By blocking COX, Diclofono reduces pain, swelling, and stiffness associated with inflammatory conditions.
What is Diclofono Used For?
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Menstrual pain (dysmenorrhea)
- Acute pain due to injury
- Migraine attacks
Common Dosages
Diclofono is available in the following forms and strengths:
- Tablets: 50 mg, 75 mg, 100 mg extended-release
- Topical gel: 1%, 3%
- Topical patch: 1.3%
Typical Dosing
FDA Approved Indications
- For pain relief in arthritis, the typical dose is 50 mg to 75 mg orally two to three times daily.
- For topical use, apply a thin layer of the 1% gel to the affected area up to four times daily.
Who Shouldn't Take Diclofono?
Diclofono should not be used in individuals with:
- Allergies to aspirin or other NSAIDs
- History of gastrointestinal bleeding or ulcers
- Severe liver or kidney disease
- History of heart attack or stroke
Advice From The Pharmacist
- Take Diclofono with food or milk to reduce stomach upset.
- Do not apply the topical gel or patch to broken skin or irritated areas.
- Avoid drinking alcohol while using Diclofono, as this increases the risk of stomach bleeding.
- Inform your healthcare provider if you experience any side effects such as abdominal pain, bloody stools, or chest pain while taking this medication.
Side Effects of Diclofono
Common Side Effects
- Stomach pain or upset
- Nausea
- Diarrhea
- Dizziness
- Headache
Uncommon/Severe Side Effects
- Gastrointestinal bleeding or ulcers
- Heart attack or stroke
- Kidney damage
- Liver toxicity
- Severe allergic reactions
Risks and Warnings of Diclofono
Cardiovascular Risk: Diclofono, like other NSAIDs, can increase the risk of heart attack and stroke, especially with long-term use.
Gastrointestinal Risk: Diclofono can cause serious gastrointestinal side effects, including ulcers, bleeding, and perforation, especially in older adults or those taking high doses.
Renal and Hepatic Risk: Prolonged use can impair kidney and liver function. Regular monitoring may be necessary, especially in patients with pre-existing conditions.
Interactions with Diclofono
Common Drug Interactions
- Anticoagulants (e.g., warfarin): Increases the risk of bleeding.
- Other NSAIDs or corticosteroids: Combining these increases the risk of gastrointestinal side effects.
- ACE inhibitors or diuretics: Diclofono may reduce the effectiveness of these medications for blood pressure control.
Alternatives to Diclofono
- Ibuprofen (Advil, Motrin): A commonly used over-the-counter NSAID for pain and inflammation.
- Naproxen (Aleve): Another NSAID often used for arthritis, muscle pain, and menstrual cramps.
- Celecoxib (Celebrex): A COX-2 selective NSAID that may have fewer gastrointestinal side effects.
- Acetaminophen (Tylenol): An alternative for pain relief without anti-inflammatory effects and with a lower risk of gastrointestinal issues.
