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Diclona
Diclona (generic name: diclofenac) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain and inflammation associated with conditions such as arthritis, muscle pain, and injuries. It works by reducing hormones that cause inflammation and pain in the body. Diclona is typically prescribed for acute pain relief or for chronic conditions requiring ongoing management of inflammation.
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Frequently Asked Questions
How long does it take for Diclona to work?
Diclona typically begins to relieve pain within 30 minutes to 1 hour after oral administration. Full anti-inflammatory effects may take several days to develop with regular use.
Can I take Diclona for long-term pain management?
Diclona can be used long-term under a doctor’s supervision, but regular monitoring is recommended due to potential risks, such as gastrointestinal or cardiovascular issues.
What should I do if I miss a dose of Diclona?
If you miss a dose, take it as soon as you remember. If it's close to your next dose, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Can I take Diclona with alcohol?
Alcohol should be avoided or limited while taking Diclona, as it can increase the risk of stomach bleeding and ulcers.
Is Diclona safe for pregnant women?
Diclona should be avoided during pregnancy, especially in the third trimester, as it can cause complications. Always consult your doctor before taking any medication during pregnancy.
Comprehensive Drug Guide
How Does Diclona Work?
Diclona works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, which are involved in the production of prostaglandins, substances that cause inflammation, pain, and fever. By reducing prostaglandin production, Diclona helps relieve pain and inflammation.
Common Dosages
- 50 mg tablets
- 75 mg extended-release tablets
- Topical gel (1% or 3% diclofenac)
- Injectable solution
Typical Dosing
- For osteoarthritis or rheumatoid arthritis: The usual oral dose is 50 mg taken 2 to 3 times daily, or 75 mg extended-release once or twice daily. The topical gel is applied 2 to 4 times daily as directed by your doctor.
Typical Dosing
FDA Approved Indications
- Osteoarthritis
- Rheumatoid arthritis
- Ankylosing spondylitis
- Acute pain
- Menstrual pain (dysmenorrhea)
Who Shouldn't Take Diclona?
- History of allergic reactions to NSAIDs (e.g., aspirin or ibuprofen)
- Active gastrointestinal ulcers or bleeding
- Severe kidney or liver disease
- Recent heart attack or stroke
Advice From The Pharmacist
- Take Diclona with food or a full glass of water to reduce the risk of stomach upset.
- Use the lowest effective dose for the shortest duration possible to minimize the risk of side effects.
- Avoid using other NSAIDs (e.g., ibuprofen, naproxen) while taking Diclona, as this increases the risk of side effects.
Side Effects of Diclona
Common Side Effects
- Stomach pain or upset
- Nausea
- Diarrhea
- Dizziness
Uncommon/Severe Side Effects
- Gastrointestinal bleeding
- Heart attack or stroke
- Liver damage
Risks and Warnings of Diclona
- Gastrointestinal Risk: NSAIDs like Diclona can increase the risk of serious gastrointestinal issues, including bleeding, ulcers, and perforation of the stomach or intestines.
- Cardiovascular Risk: Diclona may increase the risk of serious cardiovascular events such as heart attack or stroke, particularly with long-term use or in individuals with preexisting heart conditions.
Interactions with Diclona
Common Drug Interactions
- Anticoagulants (such as warfarin): Diclona can increase the risk of bleeding when taken with blood thinners.
- Other NSAIDs: Combining Diclona with other NSAIDs increases the risk of gastrointestinal side effects.
- Diuretics and ACE inhibitors: Diclona may reduce the effectiveness of these medications and increase the risk of kidney damage.
Alternatives to Diclona
- Ibuprofen: Another commonly used NSAID for pain and inflammation.
- Naproxen: An NSAID used for similar indications with a longer duration of action.
- Celecoxib (Celebrex): A COX-2 selective NSAID with a lower risk of gastrointestinal side effects.
