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Naprosyn
Naprosyn (naproxen) is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and lower fever. It is commonly prescribed for various conditions, including arthritis, musculoskeletal disorders, and menstrual pain. Naprosyn is effective in managing mild to moderate pain and is available in both prescription and over-the-counter formulations.
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Frequently Asked Questions
How quickly does Naprosyn work?
Many patients may start to feel relief within a few hours, but it may take several days for optimal effects, especially in chronic conditions.
Can I take Naprosyn with food?
Yes, taking Naprosyn with food or milk can help reduce gastrointestinal side effects.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up.
Is it safe to use Naprosyn during pregnancy?
Naprosyn should be used during pregnancy only if the potential benefits outweigh the risks. Consult your healthcare provider for guidance, especially in the third trimester.
What are the signs of serious side effects to watch for?
Monitor for symptoms of gastrointestinal bleeding (such as black or bloody stools), severe allergic reactions, or chest pain, and contact your healthcare provider immediately if these occur.
Comprehensive Drug Guide
How Does Naprosyn Work?
Naprosyn works by inhibiting the enzymes cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2), which play a key role in the production of prostaglandins—substances that mediate inflammation, pain, and fever. By reducing the levels of prostaglandins, naproxen alleviates pain and decreases inflammation.
Common Dosages
- Tablets: 250 mg, 375 mg, and 500 mg.
- Suspension: 125 mg/5 mL.
Typical Dosing
- Adults: The usual starting dose is 500 mg to 1000 mg per day, divided into two doses. The maximum recommended daily dose is 1500 mg.
- Children: Dosing for pediatric patients should be determined by a healthcare provider based on weight and condition.
Typical Dosing
FDA Approved Indications
- Treatment of osteoarthritis
- Treatment of rheumatoid arthritis
- Relief of mild to moderate pain (including menstrual pain)
- Management of ankylosing spondylitis
Who Shouldn't Take Naprosyn?
- Known hypersensitivity to naproxen or any component of the formulation
- Active gastrointestinal bleeding or ulcers
- Severe heart failure
- Kidney disease
Advice From The Pharmacist
- Take Naprosyn with food or milk to reduce gastrointestinal irritation.
- Monitor for signs of gastrointestinal bleeding, such as black or bloody stools.
- Avoid taking other NSAIDs concurrently without consulting your healthcare provider.
- Regular follow-up appointments may be necessary to monitor kidney function and overall health.
Side Effects of Naprosyn
Common Side Effects
- Gastrointestinal discomfort (nausea, dyspepsia)
- Dizziness or headache
- Fatigue
Uncommon/Severe Side Effects
- Gastrointestinal bleeding
- Severe allergic reactions (rash, itching, swelling)
- Elevated blood pressure or heart problems
Risks and Warnings of Naprosyn
- Cardiovascular Risk: Long-term use of NSAIDs, including Naprosyn, may increase the risk of heart attack or stroke. Use with caution in patients with cardiovascular risk factors.
- Gastrointestinal Risk: NSAIDs can cause serious gastrointestinal side effects, including bleeding and ulcers. Monitor for any symptoms of gastrointestinal distress.
Interactions with Naprosyn
Common Drug Interactions
- Anticoagulants: Concurrent use with blood thinners (e.g., warfarin) may increase the risk of bleeding.
- Other NSAIDs: Avoid taking other NSAIDs or high doses of aspirin without consulting your healthcare provider.
Alternatives to Naprosyn
- Other NSAIDs: Such as ibuprofen or diclofenac for similar indications.
- Acetaminophen: For pain relief without the anti-inflammatory effects of NSAIDs.
