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NiHowdy > Drug Classes > Calcium Channel Blockers

Browse Medications by Drug Class: Calcium Channel Blockers

Author

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed By

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked Fact checked

What are Calcium Channel Blockers?

Calcium channel blockers (CCBs) are a class of medications used to manage cardiovascular conditions such as high blood pressure, angina, and certain arrhythmias. They work by inhibiting calcium ions from entering the cells of the heart and blood vessel walls, resulting in relaxation of the blood vessels and reduced workload on the heart. This action improves blood flow and lowers blood pressure. A unique characteristic of CCBs is their dual action, as some types primarily target the heart while others target blood vessels, allowing for tailored treatment. NiHowdy ensures affordable access to calcium channel blockers, helping patients manage cardiovascular health effectively.

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List of drugs in Calcium Channel Blockers

Drug NameMore InformationNiHowdy Prices & Bitcoin Rebate
amLODIPine Besy-Benazepril HClamLODIPine Besy-Benazepril HCl InformationamLODIPine Besy-Benazepril HCl Pricing
amLODIPine BesylateamLODIPine Besylate InformationamLODIPine Besylate Pricing
amLODIPine Besylate-ValsartanamLODIPine Besylate-Valsartan InformationamLODIPine Besylate-Valsartan Pricing
amLODIPine-AtorvastatinamLODIPine-Atorvastatin InformationamLODIPine-Atorvastatin Pricing
amLODIPine-OlmesartanamLODIPine-Olmesartan InformationamLODIPine-Olmesartan Pricing
amLODIPine-Valsartan-HCTZamLODIPine-Valsartan-HCTZ InformationamLODIPine-Valsartan-HCTZ Pricing
CaduetCaduet InformationCaduet Pricing
Calan SRCalan SR InformationCalan SR Pricing
CardizemCardizem InformationCardizem Pricing
Cardizem CDCardizem CD InformationCardizem CD Pricing
Cardizem LACardizem LA InformationCardizem LA Pricing
Cartia XTCartia XT InformationCartia XT Pricing
ConjupriConjupri InformationConjupri Pricing
ConsensiConsensi InformationConsensi Pricing
Dilt-XRDilt-XR InformationDilt-XR Pricing
dilTIAZem HCldilTIAZem HCl InformationdilTIAZem HCl Pricing
dilTIAZem HCl ERdilTIAZem HCl ER InformationdilTIAZem HCl ER Pricing
dilTIAZem HCl ER BeadsdilTIAZem HCl ER Beads InformationdilTIAZem HCl ER Beads Pricing
dilTIAZem HCl ER Coated BeadsdilTIAZem HCl ER Coated Beads InformationdilTIAZem HCl ER Coated Beads Pricing
Felodipine ERFelodipine ER InformationFelodipine ER Pricing
IsradipineIsradipine InformationIsradipine Pricing
KaterziaKaterzia InformationKaterzia Pricing
Levamlodipine MaleateLevamlodipine Maleate InformationLevamlodipine Maleate Pricing
Matzim LAMatzim LA InformationMatzim LA Pricing
niCARdipine HClniCARdipine HCl InformationniCARdipine HCl Pricing
NIFEdipineNIFEdipine InformationNIFEdipine Pricing
NIFEdipine ERNIFEdipine ER InformationNIFEdipine ER Pricing
NIFEdipine ER Osmotic ReleaseNIFEdipine ER Osmotic Release InformationNIFEdipine ER Osmotic Release Pricing
niMODipineniMODipine InformationniMODipine Pricing
Nisoldipine ERNisoldipine ER InformationNisoldipine ER Pricing
NorliqvaNorliqva InformationNorliqva Pricing
NorvascNorvasc InformationNorvasc Pricing
NymalizeNymalize InformationNymalize Pricing
PrialtPrialt InformationPrialt Pricing
Procardia XLProcardia XL InformationProcardia XL Pricing
SularSular InformationSular Pricing
Taztia XTTaztia XT InformationTaztia XT Pricing
Tiadylt ERTiadylt ER InformationTiadylt ER Pricing
TiazacTiazac InformationTiazac Pricing
Verapamil HClVerapamil HCl InformationVerapamil HCl Pricing
Verapamil HCl ERVerapamil HCl ER InformationVerapamil HCl ER Pricing
VerelanVerelan InformationVerelan Pricing
Verelan PMVerelan PM InformationVerelan PM Pricing

Brief history about Calcium Channel Blockers?

Calcium channel blockers were first introduced in the 1960s, with the development of verapamil marking the beginning of their clinical use. The subsequent discovery of nifedipine in the 1970s provided an effective option for managing high blood pressure and angina. Over the years, newer CCBs, such as amlodipine and diltiazem, have been developed to offer improved efficacy and safety profiles. Today, CCBs are a cornerstone in cardiovascular therapy, widely prescribed for hypertension and other heart-related conditions. NiHowdy simplifies access to these essential medications, ensuring they remain affordable and accessible for patients in need.

How do Calcium Channel Blockers work?

Calcium channel blockers work by inhibiting the movement of calcium ions into the cells of the heart and vascular smooth muscle through voltage-gated calcium channels. This action reduces the strength of heart contractions and relaxes blood vessels, leading to decreased blood pressure and improved oxygen supply to the heart. For example, dihydropyridine CCBs like amlodipine primarily act on blood vessels, while non-dihydropyridine CCBs like verapamil and diltiazem affect both the heart and blood vessels. NiHowdy ensures patients can access these medications affordably, empowering them to manage their cardiovascular health effectively.

What are Calcium Channel Blockers used to treat?

Hypertension (High Blood Pressure)

Calcium channel blockers, such as amlodipine and nifedipine, are first-line treatments for hypertension. By relaxing blood vessels, they lower blood pressure and reduce the risk of complications like heart attack and stroke.

Angina

CCBs like verapamil and diltiazem are used to treat angina (chest pain) by improving blood flow to the heart and reducing its workload. They are particularly effective for managing stable angina and variant angina.

Arrhythmias

Non-dihydropyridine CCBs, such as verapamil and diltiazem, are prescribed to control certain arrhythmias, including atrial fibrillation and supraventricular tachycardia. They help stabilize the heart's rhythm by slowing electrical conduction.

Who should consider Calcium Channel Blockers medications?

Adults

Calcium channel blockers are commonly prescribed for adults with high blood pressure, angina, or arrhythmias. They provide effective symptom relief and reduce the risk of complications such as heart attack and stroke.

Children

In pediatric cases, calcium channel blockers may be used to treat certain heart conditions, such as arrhythmias or hypertension. Dosages are carefully adjusted to ensure safety and efficacy.

Seniors

Seniors with cardiovascular conditions benefit significantly from CCBs. These medications help reduce blood pressure, improve heart function, and alleviate symptoms of angina. Close monitoring is essential to adjust doses and manage potential side effects, such as swelling or dizziness.

Are Calcium Channel Blockers safe?

Calcium channel blockers are generally safe when used as directed. Common side effects include swelling of the ankles, headache, dizziness, and flushing. Rare but serious risks include low blood pressure, slow heart rate, or heart failure, particularly with non-dihydropyridine CCBs. Patients should discuss their medical history and current medications with their healthcare provider to ensure proper use and monitoring.

Can I take Calcium Channel Blockers during pregnancy?

Certain calcium channel blockers, such as nifedipine, are considered safe for use during pregnancy to manage conditions like high blood pressure. However, the decision to use these medications should be made in consultation with a healthcare provider, considering the risks and benefits.

Are Calcium Channel Blockers safe to take while lactating?

Some calcium channel blockers, such as nifedipine, are considered safe to use while breastfeeding, with minimal transfer into breast milk. Patients should consult their healthcare provider to determine the best course of treatment during lactation.

Are Calcium Channel Blockers controlled substances?

Calcium channel blockers are not classified as controlled substances. They require a prescription to ensure proper use and monitoring, particularly for long-term management of cardiovascular conditions.

Side effects of Calcium Channel Blockers?

Common side effects of calcium channel blockers include dizziness, headache, flushing, and swelling of the ankles or feet. Non-dihydropyridine CCBs may also cause bradycardia or constipation. Rare but serious risks include heart block or worsening of heart failure in susceptible patients. Patients experiencing severe or persistent side effects should consult their healthcare provider promptly.

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Cost considerations and insurance coverage for Calcium Channel Blockers

The cost of calcium channel blockers varies depending on the specific medication and formulation. Generic options like amlodipine and verapamil are widely available and affordable, while brand-name drugs may be more expensive. Many insurance plans cover these medications for approved indications, such as hypertension and angina. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these essential treatments remain accessible and cost-effective.

How do I get rebates on Calcium Channel Blockers?

NiHowdy's Bitcoin rebate program for calcium channel blocker prescriptions provides patients with a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing cardiovascular conditions both affordable and rewarding, improving access to essential care while building long-term value.

Therapeutic Classes linked to Calcium Channel Blockers

Medical Conditions treated by Calcium Channel Blockers