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dilTIAZem HCl ER Beads
dilTIAZem HCl ER Beads are a calcium channel blocker used to treat hypertension (high blood pressure) and chronic stable angina (chest pain). It works by relaxing the blood vessels, allowing blood to flow more easily, and reducing the workload on the heart. dilTIAZem HCl ER Beads are designed for extended-release, providing consistent blood pressure control throughout the day with a once-daily dose.
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Frequently Asked Questions
How long does it take for dilTIAZem HCl ER Beads to start working?
The effects on blood pressure may be noticeable within 2 to 4 weeks of starting treatment, though you may see some improvement within the first few days.
Can I stop taking dilTIAZem HCl ER Beads suddenly?
No, you should not stop taking dilTIAZem HCl ER Beads abruptly without consulting your healthcare provider. Stopping suddenly may cause a rebound increase in blood pressure or worsen angina.
What should I do if I miss a dose of dilTIAZem HCl ER Beads?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose. Do not double the dose to make up for the missed one.
Is dilTIAZem HCl ER Beads safe during pregnancy?
dilTIAZem HCl ER Beads should only be used during pregnancy if clearly needed. Always consult your healthcare provider before using this medication during pregnancy.
Can dilTIAZem HCl ER Beads be taken with other heart medications?
Yes, but some heart medications, such as beta-blockers and digoxin, may interact with dilTIAZem, leading to increased risk of bradycardia or other side effects. Always inform your healthcare provider about all medications you are taking.
Comprehensive Drug Guide
How Does dilTIAZem HCl ER Beads Work?
dilTIAZem HCl works by inhibiting the movement of calcium ions into the smooth muscle cells of the heart and blood vessels. This relaxation of the vascular smooth muscle results in lower blood pressure and decreased oxygen demand by the heart, reducing the risk of chest pain and heart attacks.
What is dilTIAZem HCl ER Beads Used For?
- Management of hypertension
- Chronic stable angina
- Control of heart rate in certain arrhythmias
Common Dosages
dilTIAZem HCl ER Beads are available in extended-release capsules, typically in the following strengths:
- 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg
Typical Dosing
FDA Approved Indications
- The usual starting dose for hypertension is 180 mg to 240 mg once daily.
- For angina, the dose may range from 120 mg to 360 mg once daily, depending on the patient’s response.
- The dose can be adjusted based on therapeutic response, with the maximum dose being 480 mg to 540 mg daily.
Who Shouldn't Take dilTIAZem HCl ER Beads?
dilTIAZem HCl ER Beads should not be used in individuals with:
- Severe hypotension
- Sick sinus syndrome or second- or third-degree AV block without a pacemaker
- Recent myocardial infarction with pulmonary congestion
- Known hypersensitivity to dilTIAZem
Advice From The Pharmacist
- Take dilTIAZem HCl ER Beads at the same time each day, and swallow the capsules whole. Do not crush or chew the beads, as this will release the medication too quickly and may increase the risk of side effects.
- If you have difficulty swallowing capsules, consult your doctor about alternative dosing options or instructions for opening the capsule and sprinkling the beads on food.
- Avoid grapefruit juice while taking dilTIAZem HCl ER Beads, as it can increase the drug levels in your blood and raise the risk of side effects.
- Notify your healthcare provider if you experience side effects such as dizziness, swelling of the feet or ankles, or slow heart rate.
Side Effects of dilTIAZem HCl ER Beads
Common Side Effects
- Dizziness or lightheadedness
- Headache
- Fatigue
- Swelling in the ankles or feet (edema)
- Nausea
Uncommon/Severe Side Effects
- Bradycardia (slow heart rate)
- Severe hypotension (low blood pressure)
- Worsening heart failure
- Liver dysfunction (elevated liver enzymes)
Risks and Warnings of dilTIAZem HCl ER Beads
Heart Failure: dilTIAZem can worsen heart failure in some patients by reducing the heart’s ability to pump blood. Patients with heart failure should be closely monitored.
Low Blood Pressure: dilTIAZem may cause a significant drop in blood pressure, especially when combined with other antihypertensive medications.
Bradycardia and AV Block: This medication can slow heart rate and cause heart block, particularly in patients with existing conduction issues.
Interactions with dilTIAZem HCl ER Beads
Common Drug Interactions
- Beta-blockers: Combining dilTIAZem with beta-blockers increases the risk of bradycardia and heart failure.
- Digoxin: dilTIAZem can increase blood levels of digoxin, leading to a higher risk of toxicity.
- CYP3A4 inhibitors: Medications like ketoconazole and clarithromycin can increase dilTIAZem levels and the risk of side effects.
- Statins: Using certain statins (e.g., simvastatin) with dilTIAZem may increase the risk of muscle-related side effects such as myopathy.
Alternatives to dilTIAZem HCl ER Beads
- Amlodipine (Norvasc): A calcium channel blocker often used for hypertension and angina, with fewer effects on heart rate.
- Verapamil: Another calcium channel blocker used to treat hypertension and arrhythmias.
- ACE inhibitors (e.g., lisinopril): Commonly prescribed for hypertension and heart failure.
- Beta-blockers (e.g., metoprolol): Used to manage high blood pressure and heart rate control.
