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Digoxin
Digoxin is a prescription medication that falls under the category of drugs known as digitalis glycosides. It's primarily used to treat heart arrhythmias and heart failure. With its potential common side effects like nausea, diarrhea, and visual disturbances, your health professional will evaluate the benefits against these drawbacks.
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Frequently Asked Questions
Can Digoxin affect my vision?
Yes, digoxin can potentially cause changes in color vision or blurred vision. If you notice unexpected changes in your vision, contact your healthcare professional promptly.
Can Digoxin be used for anxiety?
Digoxin is not typically utilized for anxiety. It's primarily used for heart conditions.
Can I just stop taking Digoxin after my symptoms are gone?
No, not without your doctor's advice. Stopping this medication suddenly can make your condition worse.
Can I take multivitamins while on Digoxin?
Yes, you can. But always inform your doctor about all medications and dietary supplements you're using.
Does Digoxin affect blood pressure?
Yes, digoxin can decrease blood pressure by reducing the heart rate.
How to store Digoxin?
It is advised to store at room temperature, away from light and moisture. Keep out of reach of children and pets!
I missed a dose of Digoxin, what should I do?
If it's almost time for your next dose, skip the missed one and keep to your regular schedule. However, if it's still some hours away, take the missed dose. Never double dose!
Is it okay if I miss a dose of Digoxin?
If you miss a dose of digoxin, take it as soon as you remember. However, if it's close to your next dose time, skip the missed dose and continue with your regular schedule.
Is weight gain a side effect of Digoxin?
Digoxin does not typically cause weight gain. However, if you experience sudden weight gain, especially with shortness of breath or swelling in ankles or feet, seek immediate medical attention.
Comprehensive Drug Guide
How Does Digoxin Work?
Digoxin is a cardiac glycoside that augments cardiac contractility (positive inotropic effect). It also slows down the conduction speed through the atrioventricular node, controlling the heart rate.
What is Digoxin Used For?
FDA indications: Digoxin is primarily used to treat heart failure and heart arrhythmias, such as atrial fibrillation.
Offlabel uses: Less commonly, it may be used for fetal tachycardia (fast heart rate in a baby before birth), among others. Always remember that offlabel does not mean ineffective or dangerous, it's just used for purposes not officially approved by regulatory bodies
Common Dosages
Tablets: 125mcg (0.125mg), 250mcg (0.25mg)
Oral solution: 50mcg/mL
Typical Dosing
FDA Approved Indications
- Heart Failure: Starting dose of 0.125 to 0.25 mg once daily.
- Atrial Fibrillation: 0.125 to 0.25 mg once daily.
- Dosage is then adjusted based on body weight and kidney function.
Off-Label Uses
- Fetal Tachycardia: Dosage is dependent on the severity of the condition and the mother's body weight. Always to be administered under medical supervision.
Who Shouldn't Take Digoxin?
- Those who have ventricular fibrillation.
- People with a known hypersensitivity to digoxin or other digitalis medicines.
- People with certain heart conditions, like heart block without a pacemaker, or a form of heart rhythm disorder called WolffParkinsonWhite Syndrome.
- Be cautious if you have kidney disease, thyroid problems, electrolyte imbalances, or are malnourished.
- Pregnant women or breastfeeding mothers need to discuss potential risks with their healthcare provider.
Advice From The Pharmacist
- Always take this medication preferably an hour before or 2 hours after meals for better absorption.
- Do not switch brands without medical advice, as the different brands may not work the same way.
- Keep yourself hydrated, and avoid becoming overheated or dehydrated during exercise.
- Regularly monitor your pulse rate and blood tests will be needed periodically to check the drug levels in the body.
- Consult your healthcare provider immediately if you observe any symptoms like nausea, rapid weight gain, loss of appetite, blurred vision, or slow heart rate.
Side Effects of Digoxin
Common Side Effects
- Nausea, vomiting, diarrhea.
- Loss of appetite and weight loss.
- Visual disturbances like blurred vision or seeing spots.
Uncommon/Severe Side Effects
- Uncommon side effects:
- Slow or fast heartbeat.
- Weakness, drowsiness.
- Mental/mood changes.
- Rare side effects:
- Severe dizziness or fainting.
- Black or tarry stools.
- Severe side effects:
- Prolonged vomiting or diarrhea as it can make digoxin toxicity more likely.
- Irregular heartbeat, palpitations, or chest pain should be reported immediately.
- Swelling of the ankles or feet.
Risks and Warnings of Digoxin
- Taking digoxin if you have heart conditions like ventricular fibrillation or have a known hypersensitivity to digoxin or other digitalis medicines can lead to serious adverse effects.
- If you have conditions like kidney disease or thyroid problems, discuss them with your doctor before starting the medication.
- The drug can cause changes in your electrolytes (like calcium, magnesium, and potassium), and if these are already imbalanced, digoxin can potentially cause toxic effects.
- Pregnant and breastfeeding mothers should only use this medication if the potential benefit outweighs the potential risk to the fetus or baby.
Interactions with Digoxin
Common Drug Interactions
- Diuretics (like Furosemide or hydroCHLOROthiazide)
- Betablockers (like Metoprolol)
- Calcium Channel blockers (like Verapamil HCl, dilTIAZem HCl, and Amlodipine)
- Medications that affect digoxin concentration, such as Amiodarone HCl, Propafenone HCl, or Quinidine
- Certain antibiotics, like Clarithromycin or Erythromycin
