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Norvasc
Norvasc (generic name: amlodipine) is a calcium channel blocker used primarily for the treatment of hypertension (high blood pressure) and chronic stable angina (chest pain). It helps relax and widen blood vessels, improving blood flow and reducing the heart's workload.
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Frequently Asked Questions
How quickly does Norvasc work?
Norvasc typically starts to lower blood pressure within 24 hours, but it may take several weeks to see the full effects.
Can I take Norvasc with food?
Yes, Norvasc can be taken with or without food; however, consistency is important.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Norvasc?
There are no specific dietary restrictions while using Norvasc, but it is advisable to limit grapefruit juice.
Is Norvasc safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Norvasc during these periods.
Comprehensive Drug Guide
How Does Norvasc Work?
Amlodipine works by inhibiting the influx of calcium ions into vascular smooth muscle and cardiac muscle. This leads to relaxation of the smooth muscle in blood vessels, resulting in vasodilation, decreased peripheral resistance, and reduced myocardial oxygen demand.
Common Dosages
- Tablets: 2.5 mg, 5 mg, and 10 mg.
Typical Dosing
- The usual starting dose for adults is 5 mg taken orally once daily, which may be increased to 10 mg per day based on blood pressure response and tolerability.
Typical Dosing
FDA Approved Indications
- Hypertension: for the treatment of high blood pressure.
- Angina Pectoris: for the management of chronic stable angina.
Who Shouldn't Take Norvasc?
- Known hypersensitivity to amlodipine or any component of the formulation.
- Severe hypotension (low blood pressure).
- Aortic stenosis or unstable angina.
Advice From The Pharmacist
- Take Norvasc exactly as prescribed, and do not stop taking it abruptly without consulting your healthcare provider.
- Monitor blood pressure regularly to ensure effectiveness and adjust the dosage as necessary.
- Be cautious when engaging in activities that require alertness, as Norvasc may cause dizziness.
Side Effects of Norvasc
Common Side Effects
- Swelling (edema) of the legs or ankles
- Flushing
- Dizziness
- Fatigue
- Nausea
Uncommon/Severe Side Effects
- Severe hypotension
- Worsening angina
- Allergic reactions (rash, itching, swelling).
Risks and Warnings of Norvasc
- Hypotension: Monitor blood pressure closely, especially when starting treatment or adjusting doses.
- Heart Function: Use with caution in patients with heart failure or significant aortic stenosis.
Interactions with Norvasc
Common Drug Interactions
- Other Antihypertensives: Use caution when combined with other medications that lower blood pressure.
- Grapefruit Juice: May increase the levels of amlodipine; avoid excessive consumption.
Alternatives to Norvasc
- Other Calcium Channel Blockers: Such as diltiazem or nifedipine for managing hypertension and angina.
- ACE Inhibitors: As alternative antihypertensive options.
