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Norliqva
Norliqva (generic name: quintessentially or quetiapine extended-release) is an atypical antipsychotic used to treat a variety of mental health conditions, including schizophrenia, bipolar disorder, and major depressive disorder as an adjunct therapy. It helps manage symptoms by affecting neurotransmitters in the brain, particularly serotonin and dopamine.
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Frequently Asked Questions
How quickly does Norliqva work?
Patients may begin to notice improvements in symptoms within 1 to 2 weeks, although full effects may take longer.
Can I take Norliqva with food?
Yes, Norliqva can be taken with or without food.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.
Are there any dietary restrictions while using Norliqva?
There are no specific dietary restrictions while using Norliqva.
Is Norliqva safe during pregnancy or breastfeeding?
Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Norliqva during these periods.
Comprehensive Drug Guide
How Does Norliqva Work?
Quetiapine works by antagonizing various neurotransmitter receptors in the brain, primarily serotonin (5-HT2A) and dopamine (D2) receptors. This action helps to stabilize mood and reduce symptoms of psychosis, such as hallucinations and delusions.
Common Dosages
- Extended-Release Tablets: Common strengths include 50 mg, 150 mg, 300 mg, and 400 mg.
Typical Dosing
- For schizophrenia, the usual starting dose is 300 mg once daily, which may be adjusted based on clinical response, with a maximum dose of 800 mg per day.
- For bipolar disorder, the dosage may vary based on whether it is being used for manic or depressive episodes.
Typical Dosing
FDA Approved Indications
- Schizophrenia: for the treatment of adults and adolescents.
- Bipolar Disorder: for the treatment of manic and depressive episodes.
- Major Depressive Disorder: as an adjunct to antidepressant therapy in adults.
Who Shouldn't Take Norliqva?
- Known hypersensitivity to quetiapine or any component of the formulation.
- History of severe allergic reactions to other antipsychotics.
Advice From The Pharmacist
- Take Norliqva exactly as prescribed, and do not stop taking it abruptly without consulting your healthcare provider.
- Monitor for side effects, especially during the initial treatment phase or when doses are adjusted.
- Regular follow-ups may be necessary to evaluate treatment effectiveness and monitor for potential side effects.
Side Effects of Norliqva
Common Side Effects
- Drowsiness or sedation
- Dizziness
- Dry mouth
- Weight gain
- Increased appetite
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Neuroleptic malignant syndrome (NMS)
- Tardive dyskinesia (involuntary movements).
Risks and Warnings of Norliqva
- Metabolic Changes: Monitor for weight gain, diabetes, and lipid levels; regular assessments are recommended.
- Sedation: Use caution when engaging in activities that require alertness, as sedation is a common side effect.
Interactions with Norliqva
Common Drug Interactions
- CNS Depressants: Use caution when combining with other central nervous system depressants, as this may enhance sedative effects.
- Other Antipsychotics: Be cautious of potential additive effects and drug interactions.
Alternatives to Norliqva
- Other Atypical Antipsychotics: Such as risperidone or aripiprazole for similar indications.
- Mood Stabilizers: For bipolar disorder, medications like lamotrigine may be considered.
