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Isradipine
Isradipine is a commonly used medication known as a calcium channel blocker. Its primary function is to help relax the muscles of your heart and blood vessels. It is essential in the treatment of high blood pressure (hypertension). Common side effects could include flushing, headache, and dizziness but they are typically outnumbered by the benefits.
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Frequently Asked Questions
Can I just stop taking Isradipine?
You should not stop taking isradipine without speaking to your doctor, as this could lead to rebound hypertension.
Can I take Isradipine if I have diabetes?
There's no restriction on taking isradipine if you have diabetes. It's always good to check with your healthcare provider, though.
Does Isradipine cause hair loss?
Hair loss is not a known side effect of isradipine.
I missed a dose of Isradipine, what should I do?
If it's close to the time for your next dose, skip the missed one. Otherwise, you can take it as soon as you remember ? just don't double up.
Comprehensive Drug Guide
How Does Isradipine Work?
Isradipine is a calcium channel blocker that inhibits the transmembrane influx of calcium ions into cardiac and vascular smooth muscle, causing a decrease in peripheral resistance and blood pressure.
What is Isradipine Used For?
FDA indications: Isradipine is predominantly used for treating hypertension, helping lower blood pressure levels, and alleviating the workload on the heart.
Offlabel uses: It has also been identified as a potential treatment for earlystage Parkinson?s disease.
Common Dosages
Capsules: 2.5mg, 5mg
Controlledrelease tablets: 5mg, 10mg
Typical Dosing
FDA Approved Indications
- Hypertension: 2.5 mg orally, two times a day; can be increased to 5 mg, two times a day.
Off-Label Uses
- Earlystage Parkinson?s disease: Dosage varies, and must be determined by the healthcare provider.
Who Shouldn't Take Isradipine?
- If you have had an allergic reaction to isradipine or any similar medication in the past.
- If you have severe heart disease or heart failure.
- If you have low blood pressure (hypotension).
- If you are pregnant, planning to become pregnant, or are breastfeeding.
Advice From The Pharmacist
- Isradipine should be taken on an empty stomach, 1 hour before meals or 2 hours after meals.
- The medication should be swallowed whole and not crushed or chewed.
- Make sure to have regular checkups with your doctor.
- Do not consume grapefruit or grapefruit juice while on isradipine as it can increase the concentration of the drug in your bloodstream.
- If you feel lightheaded or dizzy, consult with your doctor as the dose may need to be adjusted.
Side Effects of Isradipine
Common Side Effects
- You may feel dizzy or get a headache.
- Your face might appear flushed.
- You may feel tired or experience warmth in your face.
Uncommon/Severe Side Effects
- Uncommon side effects:
- You may experience an upset stomach or constipation.
- You may develop a rash or itch.
- Rare side effects:
- You may have difficulty sleeping
- Have a rapid or irregular heartbeat.
- Severe side effects:
- You may experience chest pain or shortness of breath.
- You might have swollen hands or feet.
Risks and Warnings of Isradipine
- If you have any allergies, especially to dihydropyridines, inform your doctor before starting this medication.
- It's advised to avoid isradipine if you have heart or liver diseases which may worsen under its influence.
- Do not abruptly stop using isradipine as it may exacerbate your hypertension.
- If you are pregnant, planning to become pregnant, or are breastfeeding, ensure to talk with your doctor about possible risks before starting this medication.
Interactions with Isradipine
Common Drug Interactions
- Digitalis
- Betablockers
- Cimetidine
- Grapefruit juice
Alternatives to Isradipine
- Amlodipine
- Nisoldipine
- Nicardipine
- Nifedipine
- Felodipine
