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Cimetidine
Cimetidine is a type of medication known as an H2 blocker. Primarily, it's used to reduce the amount of acid your stomach produces, which makes it suitable for treating conditions such as ulcers and gastroesophageal reflux disease (GERD).
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Frequently Asked Questions
Can I take Cimetidine if I have kidney disease?
Yes, however, dosage adjustments may be necessary. Always consult with a healthcare provider.
Will Cimetidine make me drowsy?
Dizziness and fatigue can occur but are not extremely common. Always consult with a healthcare provider, and do not drive or operate machinery until you know how this medication affects you.
What should I do if I miss a dose of Cimetidine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose. Never take two doses at one time.
Can I stop taking Cimetidine abruptly?
It is not advised to stop taking cimetidine suddenly. Always consult your healthcare provider first.
Comprehensive Drug Guide
How Does Cimetidine Work?
Cimetidine, an H2-receptor antagonist, works by blocking histamine at the receptors of acid-producing parietal cells in the stomach. Thus, it decreases the amount of gastric acid present in your stomach.
What is Cimetidine Used For?
Cimetidine is used to treat conditions such as ulcers of the stomach and intestines and gastroesophageal reflux disease (GERD), a condition where the acid in the stomach washes back up into the esophagus.
Common Dosages
- Tablets: 200mg (over the counter), 300mg, 400mg, 800mg (prescription)
- Injection: 150mg/mL
- Liquid: 300mg/5mL (prescription)
Typical Dosing
FDA Approved Indications
- Ulcers: 800mg at bedtime or 400mg twice daily.
- GERD: 800mg at bedtime.
Pediatric Dosing
- Pediatric dosing of cimetidine depends on what condition it's being used for and the child's weight. Always follow the doctor's instructions.
- Children may need a lower dose than adults, depending on their weight and the severity of their symptoms.
- Be aware that long-term use can affect the absorption of other medicines in children, so regular check-ups are important.
- Also, keep an eye out for mood changes or unusual tiredness in kids taking this med.
- Don't stop giving this medicine to your child suddenly as it may lead to withdrawal symptoms. Always follow your doctor's instructions about tapering the dose.
Who Shouldn't Take Cimetidine?
- Have kidney or liver disease (dosing adjustments may be necessary).
- Have a blood disorder such as hemophilia or sickle cell anemia.
- Have a history of a weak or malfunctioning immune system (e.g. HIV).
- Have a history of stomach cancer or other problems (such as acid reflux).
- Have experienced an allergic reaction to cimetidine in the past.
- Are pregnant, planning to become pregnant, or breastfeeding.
- Are taking certain medications (e.g., warfarin, clopidogrel, carbamazepine) that may interact negatively with cimetidine.
Advice From The Pharmacist
- Take cimetidine with or without food.
- Take this medication as prescribed by your doctor, usually 2 or 4 times daily.
- Do not take over-the-counter cimetidine for longer than two weeks unless directed by your doctor.
- Inform your healthcare provider immediately if your symptoms continue after two weeks of self-treatment with cimetidine or if they worsen at any time.
Side Effects of Cimetidine
Common Side Effects
- You might have headaches.
- You might feel dizzy or tired.
Uncommon/Severe Side Effects
- You might suffer from an irregular heartbeat.
- If you notice signs of infection (e.g., fever, persistent sore throat), severe nausea, vomiting, fatigue, weakness, or dark-colored urine, seek medical help immediately.
Risks and Warnings of Cimetidine
- Cimetidine is not suitable for everyone – those with kidney or liver disease, blood disorders like hemophilia, or stomach cancer might need to exercise caution or avoid this drug altogether.
- Those with a history of a weak immune system, such as HIV patients, should consult their healthcare provider about the safety of cimetidine.
- If you're pregnant, planning to become pregnant, or breastfeeding, ensure to get medical advice before using cimetidine.
- Always notify your healthcare provider if you're taking any other medications, as cimetidine may interact with other drugs such as warfarin, clopidogrel, and carbamazepine.
Interactions with Cimetidine
Common Drug Interactions
- Warfarin
- Phenobarbital
- Phenytoin
- Carbamazepine
- Diazepam
- Theophylline
- Lidocaine
- Clopidogrel
Alternatives to Cimetidine
- Ranitidine
- Famotidine
- Nizatidine
- Esomeprazole
- Lansoprazole
- Omeprazole
