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dilTIAZem HCl ER Coated Beads

dilTIAZem HCl ER Coated Beads are a calcium channel blocker used for managing hypertension (high blood pressure) and chronic stable angina (chest pain). The extended-release coated beads allow for a consistent release of the medication over time, helping to control blood pressure and reduce heart strain with a once-daily dose. dilTIAZem helps relax the blood vessels and lowers the heart’s demand for oxygen, making it useful in treating cardiovascular conditions.



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Frequently Asked Questions

How long does it take for dilTIAZem HCl ER Coated Beads to start working?
Open FAQClose FAQ

The effects on blood pressure may become noticeable within 2 to 4 weeks of starting treatment, although some improvement may be seen earlier.

Can I stop taking dilTIAZem HCl ER Coated Beads abruptly?
Open FAQClose FAQ

No, stopping dilTIAZem suddenly can lead to a rebound increase in blood pressure or worsen angina. Always consult your healthcare provider before discontinuing the medication.

What should I do if I miss a dose?
Open FAQClose FAQ

Take the missed dose as soon as you remember, unless it’s close to your next scheduled dose. Do not double the dose to make up for the missed one.

Is dilTIAZem HCl ER Coated Beads safe during pregnancy?
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dilTIAZem should be used during pregnancy only if clearly needed. Always consult your healthcare provider before using this medication during pregnancy.

Can I take dilTIAZem HCl ER Coated Beads with other heart medications?
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Yes, but it’s important to inform your healthcare provider about all medications you're taking, as some heart medications, such as beta-blockers and digoxin, can interact with dilTIAZem, potentially leading to increased side effects or complications.

Comprehensive Drug Guide

How Does dilTIAZem HCl ER Coated Beads Work?

dilTIAZem HCl ER Coated Beads work by inhibiting the movement of calcium ions into smooth muscle cells in the heart and blood vessels. This causes the blood vessels to relax, lowering blood pressure and decreasing the heart's workload. By slowing down the heart rate and improving blood flow, dilTIAZem reduces the occurrence of chest pain (angina).



What is dilTIAZem HCl ER Coated Beads Used For?

  • Management of hypertension
  • Chronic stable angina
  • Heart rate control in certain arrhythmias


Common Dosages

dilTIAZem HCl ER Coated Beads are available in the following strengths:

  • 120 mg, 180 mg, 240 mg, 300 mg, 360 mg, 420 mg

Typical Dosing

FDA Approved Indications

  • The typical starting dose for hypertension is 180 mg to 240 mg once daily.
  • For angina, the dose may range from 120 mg to 360 mg once daily, depending on the patient’s response.
  • The dose can be adjusted based on clinical response, with a maximum dose of 540 mg daily.

Who Shouldn't Take dilTIAZem HCl ER Coated Beads?

dilTIAZem HCl ER Coated Beads should not be used in individuals with:

  • Severe hypotension
  • Second- or third-degree AV block (without a pacemaker)
  • Sick sinus syndrome (without a pacemaker)
  • Recent myocardial infarction with pulmonary congestion
  • Known hypersensitivity to dilTIAZem

Advice From The Pharmacist

  • Swallow the capsule whole. Do not crush, chew, or open the capsule, as this can cause the medication to be released too quickly.
  • Take the medication at the same time each day to maintain consistent blood levels.
  • Avoid consuming grapefruit or grapefruit juice, as it can increase the level of dilTIAZem in your blood, raising the risk of side effects.
  • If you experience symptoms like dizziness, slow heart rate, or swelling of the feet or ankles, contact your healthcare provider.


Side Effects of dilTIAZem HCl ER Coated Beads

Common Side Effects

  • Dizziness or lightheadedness
  • Fatigue
  • Headache
  • Swelling in the ankles or feet (edema)
  • Nausea


Uncommon/Severe Side Effects

  • Bradycardia (slow heart rate)
  • Severe hypotension
  • Worsening heart failure
  • Liver dysfunction (elevated liver enzymes)


Risks and Warnings of dilTIAZem HCl ER Coated Beads

Heart Failure: dilTIAZem can worsen heart failure in some patients by reducing the heart's ability to pump blood effectively. Patients with heart failure should be closely monitored.

Bradycardia: dilTIAZem can cause a slow heart rate, especially when used in combination with other heart medications like beta-blockers.

Low Blood Pressure: dilTIAZem may cause significant drops in blood pressure, particularly in patients taking other antihypertensive medications.


Interactions with dilTIAZem HCl ER Coated Beads

Common Drug Interactions

  • Beta-blockers: Combining dilTIAZem with beta-blockers (e.g., metoprolol) can increase the risk of bradycardia and heart failure.
  • Digoxin: dilTIAZem may increase digoxin levels, leading to an increased risk of toxicity.
  • CYP3A4 inhibitors: Drugs like ketoconazole and erythromycin can increase the level of dilTIAZem in the blood, raising the risk of side effects.
  • Statins: Some statins (e.g., simvastatin) may increase the risk of muscle-related side effects when used with dilTIAZem.


Alternatives to dilTIAZem HCl ER Coated Beads

  • Amlodipine (Norvasc): Another calcium channel blocker used to manage hypertension and angina.
  • Verapamil: A calcium channel blocker that can be used for blood pressure management and arrhythmias.
  • ACE inhibitors: Such as lisinopril, which are used to lower blood pressure and reduce the risk of cardiovascular events.
  • Beta-blockers: Such as atenolol, often used to lower blood pressure and control heart rate.