NiHowdy > Drug Classes > Benzodiazepines

Browse Medications by Drug Class: Benzodiazepines

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Benzodiazepines?

Benzodiazepines are a class of medications that act as central nervous system (CNS) depressants, commonly used to treat anxiety, insomnia, muscle spasms, and seizures. They work by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter that reduces brain activity, leading to calming, sedative, or anticonvulsant effects. Benzodiazepines are known for their rapid onset of action and effectiveness in acute and short-term management of various conditions. NiHowdy ensures affordable access to benzodiazepines, helping patients safely manage conditions requiring these medications.

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List of drugs in Benzodiazepines

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

Alprazolam	Alprazolam Information	Alprazolam Pricing
ALPRAZolam ER	ALPRAZolam ER Information	ALPRAZolam ER Pricing
ALPRAZolam Intensol	ALPRAZolam Intensol Information	ALPRAZolam Intensol Pricing
ALPRAZolam XR	ALPRAZolam XR Information	ALPRAZolam XR Pricing
Ativan	Ativan Information	Ativan Pricing
chlordiazePOXIDE HCl	chlordiazePOXIDE HCl Information	chlordiazePOXIDE HCl Pricing
chlordiazePOXIDE-Amitriptyline	chlordiazePOXIDE-Amitriptyline Information	chlordiazePOXIDE-Amitriptyline Pricing
chlordiazePOXIDE-Clidinium	chlordiazePOXIDE-Clidinium Information	chlordiazePOXIDE-Clidinium Pricing
cloBAZam	cloBAZam Information	cloBAZam Pricing
clonazePAM	clonazePAM Information	clonazePAM Pricing
Clorazepate Dipotassium	Clorazepate Dipotassium Information	Clorazepate Dipotassium Pricing
Diastat AcuDial	Diastat AcuDial Information	Diastat AcuDial Pricing
Diastat Pediatric	Diastat Pediatric Information	Diastat Pediatric Pricing
diazePAM	diazePAM Information	diazePAM Pricing
diazePAM Intensol	diazePAM Intensol Information	diazePAM Intensol Pricing
Doral	Doral Information	Doral Pricing
Estazolam	Estazolam Information	Estazolam Pricing
Flurazepam HCl	Flurazepam HCl Information	Flurazepam HCl Pricing
Halcion	Halcion Information	Halcion Pricing
KlonoPIN	KlonoPIN Information	KlonoPIN Pricing
Librax	Librax Information	Librax Pricing
LORazepam	LORazepam Information	LORazepam Pricing
LORazepam Intensol	LORazepam Intensol Information	LORazepam Intensol Pricing
Loreev XR	Loreev XR Information	Loreev XR Pricing
Nayzilam	Nayzilam Information	Nayzilam Pricing
Onfi	Onfi Information	Onfi Pricing
Oxazepam	Oxazepam Information	Oxazepam Pricing
Quazepam	Quazepam Information	Quazepam Pricing
Restoril	Restoril Information	Restoril Pricing
Sympazan	Sympazan Information	Sympazan Pricing
Temazepam	Temazepam Information	Temazepam Pricing
Tranxene-T	Tranxene-T Information	Tranxene-T Pricing
Triazolam	Triazolam Information	Triazolam Pricing
Valium	Valium Information	Valium Pricing
Valtoco 10 MG Dose	Valtoco 10 MG Dose Information	Valtoco 10 MG Dose Pricing
Valtoco 15 MG Dose	Valtoco 15 MG Dose Information	Valtoco 15 MG Dose Pricing
Valtoco 20 MG Dose	Valtoco 20 MG Dose Information	Valtoco 20 MG Dose Pricing
Valtoco 5 MG Dose	Valtoco 5 MG Dose Information	Valtoco 5 MG Dose Pricing
Xanax	Xanax Information	Xanax Pricing
Xanax XR	Xanax XR Information	Xanax XR Pricing

Brief history about Benzodiazepines?

Benzodiazepines were first synthesized in the 1950s, with chlordiazepoxide (Librium) introduced in 1960 as the first widely available medication in this class. Diazepam (Valium) followed shortly after, revolutionizing the treatment of anxiety and other neurological conditions by offering a safer alternative to barbiturates. Over the years, benzodiazepines have become some of the most widely prescribed medications globally for their effectiveness and relatively lower risk of severe side effects compared to older CNS depressants. NiHowdy simplifies access to these medications, ensuring affordability for patients in need.

How do Benzodiazepines work?

Benzodiazepines work by enhancing the effects of gamma-aminobutyric acid (GABA), the brain's primary inhibitory neurotransmitter. By binding to GABA-A receptors, benzodiazepines increase the frequency of chloride ion channel opening, leading to hyperpolarization of neurons and reduced brain excitability. This mechanism results in anxiolytic (anxiety-reducing), sedative, muscle-relaxing, and anticonvulsant effects. For example, lorazepam is commonly used to manage acute anxiety, while diazepam is effective in controlling seizures. NiHowdy provides affordable access to benzodiazepines, ensuring patients receive effective treatment for their conditions.

What are Benzodiazepines used to treat?

Anxiety Disorders

Benzodiazepines like alprazolam (Xanax) and lorazepam (Ativan) are used to provide rapid relief from acute anxiety and panic attacks.

Insomnia

Medications such as temazepam and triazolam are prescribed to help individuals with short-term sleep disturbances by promoting relaxation and sleep onset.

Seizure Disorders

Diazepam and clonazepam are effective in managing seizures, including acute seizure episodes and status epilepticus.

Alcohol Withdrawal Syndrome

Benzodiazepines like chlordiazepoxide and lorazepam are used to manage symptoms of alcohol withdrawal, such as tremors, agitation, and seizures.

Muscle Spasms

Diazepam is commonly prescribed to relieve muscle spasms caused by conditions like multiple sclerosis or spinal cord injuries.

Bipolar Disorder and Agitation

Benzodiazepines can be used adjunctively to manage acute agitation or insomnia in patients with bipolar disorder.

Who should consider Benzodiazepines medications?

Adults

Benzodiazepines are frequently prescribed for adults experiencing acute anxiety, insomnia, or seizures. They provide effective relief for short-term use or as part of a comprehensive treatment plan for specific conditions.

Children

In pediatric cases, benzodiazepines like diazepam and clonazepam are used to treat certain seizure disorders or severe muscle spasms. Dosage is carefully adjusted to ensure safety and efficacy.

Seniors

Seniors may benefit from benzodiazepines for conditions like insomnia, anxiety, or seizures, but require close monitoring due to increased sensitivity to side effects such as sedation and confusion.

Are Benzodiazepines safe?

Benzodiazepines are generally safe when prescribed and used as directed for short-term relief. Common side effects include drowsiness, dizziness, and fatigue. Long-term use carries risks such as dependence, tolerance, and withdrawal symptoms. Additionally, combining benzodiazepines with alcohol or other CNS depressants increases the risk of severe respiratory depression. Patients should use these medications only under the guidance of a healthcare provider and should discuss any concerns regarding side effects or dependency.

Can I take Benzodiazepines during pregnancy?

Benzodiazepines are generally avoided during pregnancy due to potential risks to the fetus, including sedation, respiratory distress, and withdrawal symptoms at birth. However, they may be used in specific situations where the benefits outweigh the risks. Patients should consult their healthcare provider for personalized advice.

Are Benzodiazepines safe to take while lactating?

Benzodiazepines pass into breast milk and may cause sedation or other effects in nursing infants. While their use is not universally contraindicated, caution is advised. Patients should consult their healthcare provider to assess the risks and benefits and determine if alternative treatments are preferable.

Are Benzodiazepines controlled substances?

Benzodiazepines are classified as controlled substances under Schedule IV due to their potential for misuse and dependence. They require a prescription and should be used strictly as directed to avoid adverse effects and addiction. Patients must store these medications securely to prevent misuse.

Side effects of Benzodiazepines?

Common side effects of benzodiazepines include drowsiness, dizziness, muscle weakness, and impaired coordination. Long-term use can lead to dependence, tolerance, and withdrawal symptoms if discontinued abruptly. Serious but rare risks include respiratory depression and cognitive impairment, particularly in older adults or those with pre-existing health conditions. Patients experiencing severe or unusual side effects should consult their healthcare provider immediately.

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Cost considerations and insurance coverage for Benzodiazepines

The cost of benzodiazepines varies depending on the specific medication, dosage, and formulation. Generic options, such as diazepam and lorazepam, are generally affordable and widely available. Many insurance plans cover benzodiazepines for approved indications, including anxiety and seizure disorders. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Benzodiazepines?

NiHowdy's Bitcoin rebate program for benzodiazepine prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing anxiety, seizures, and other conditions both affordable and rewarding, improving access to critical care while building long-term value.