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Loreev XR

Loreev XR is a brand name for a formulation of venlafaxine, which is an extended-release antidepressant belonging to the class of serotonin-norepinephrine reuptake inhibitors (SNRIs). It is primarily used to treat major depressive disorder, generalized anxiety disorder, and social anxiety disorder. The extended-release formulation allows for once-daily dosing, which can help improve adherence to the treatment regimen.

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Frequently Asked Questions

How long does it take for Loreev XR to work?
Open FAQClose FAQ

Patients may start to notice improvements in their symptoms within a few weeks, but it can take up to 6 to 8 weeks for the full effect to be realized.

Can I take Loreev XR with food?
Open FAQClose FAQ

Yes, you can take Loreev XR with or without food. However, take it consistently in the same way to maintain steady levels in your system.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while taking Loreev XR?
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There are no specific dietary restrictions, but maintaining a balanced diet is advisable.

Is Loreev XR safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Loreev XR.

Comprehensive Drug Guide

How Does Loreev XR Work?

Loreev XR works by inhibiting the reuptake of two key neurotransmitters in the brain: serotonin and norepinephrine. By increasing the levels of these neurotransmitters, it helps to improve mood and alleviate anxiety symptoms. This dual action is thought to contribute to its efficacy in treating depression and anxiety disorders.

Common Dosages

  • 75 mg
  • 150 mg
  • 225 mg

Typical Dosing

  • The usual starting dose is 75 mg once daily, which may be increased based on clinical response. The maximum recommended dose is usually 225 mg per day.


Typical Dosing

FDA Approved Indications

  • Major Depressive Disorder
  • Generalized Anxiety Disorder
  • Social Anxiety Disorder


Who Shouldn't Take Loreev XR?

  • Known hypersensitivity to venlafaxine or any component of the formulation.
  • Uncontrolled narrow-angle glaucoma.
  • Recent use of monoamine oxidase inhibitors (MAOIs) or other drugs that increase serotonin levels.


Advice From The Pharmacist

  • Take Loreev XR exactly as prescribed, and do not adjust the dose without consulting your healthcare provider.
  • It is important to take the medication consistently, either with or without food.
  • Monitor for any side effects, including changes in mood or behavior, and report any concerning symptoms to your healthcare provider.


Side Effects of Loreev XR

Common Side Effects

  • Nausea
  • Dizziness
  • Insomnia
  • Dry mouth
  • Sweating


Uncommon/Severe Side Effects

  • Increased blood pressure
  • Serotonin syndrome (symptoms include confusion, rapid heart rate, and severe agitation)
  • Risk of suicidal thoughts or behaviors, particularly in young adults


Risks and Warnings of Loreev XR

  • Hypertension: Regular monitoring of blood pressure is advised, especially in patients with a history of hypertension.
  • Withdrawal Symptoms: Discontinuing Loreev XR abruptly can lead to withdrawal symptoms; tapering under a healthcare provider's supervision is recommended.
  • Suicidal Thoughts: Patients should be closely monitored for worsening depression or emergence of suicidal thoughts, particularly during the initial treatment phase or when doses are adjusted.


Interactions with Loreev XR

Common Drug Interactions

  • MAO Inhibitors: Concomitant use with MAOIs can cause serious, potentially fatal interactions.
  • Other Antidepressants: Use caution when combining with other antidepressants, particularly those that increase serotonin levels.
  • Blood Pressure Medications: Lortreev XR can potentially increase blood pressure; monitor for interactions with antihypertensive medications.


Alternatives to Loreev XR

  • Other Antidepressants: Such as selective serotonin reuptake inhibitors (SSRIs) like fluoxetine or sertraline.
  • Cognitive Behavioral Therapy (CBT): A non-pharmacological approach that can be effective for anxiety and depression.