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Restoril
Restoril (generic name: temazepam) is a prescription benzodiazepine used to treat insomnia, specifically for patients who have trouble falling asleep or staying asleep. Restoril works by enhancing the activity of gamma-aminobutyric acid (GABA), a neurotransmitter in the brain that produces a calming effect, which helps patients fall asleep faster and stay asleep longer. It is typically used for short-term treatment of insomnia, as long-term use can lead to dependence or tolerance.
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Frequently Asked Questions
How long does Restoril take to work?
Restoril works relatively quickly, usually within 15 to 30 minutes of taking the dose, helping patients fall asleep faster.
Can I take Restoril every night?
Restoril is intended for short-term use only (7 to 10 days). Taking it every night for extended periods increases the risk of dependence and tolerance. Discuss long-term treatment options with your doctor if insomnia persists.
Does Restoril cause next-day drowsiness?
Restoril can cause next-day drowsiness or a "hangover effect," especially if you do not get a full 7 to 8 hours of sleep. Taking the medication too late at night or at higher doses can increase this risk.
Can I stop taking Restoril abruptly?
No, stopping Restoril suddenly can lead to withdrawal symptoms, including seizures, tremors, and anxiety. Your doctor will guide you on how to gradually reduce the dose if needed.
Is Restoril safe for elderly patients?
Elderly patients may be more sensitive to the effects of Restoril and are at a higher risk for falls, dizziness, and confusion. Lower doses or alternative treatments are often recommended for older adults.
Comprehensive Drug Guide
How Does Restoril Work?
Restoril enhances the effects of gamma-aminobutyric acid (GABA), a neurotransmitter that inhibits activity in the brain, creating a calming effect. By increasing GABA activity, Restoril helps to reduce anxiety, relax muscles, and promote sleep. It decreases the time it takes to fall asleep and reduces nighttime awakenings, making it useful for short-term treatment of insomnia.
Common Dosages
- 7.5 mg capsules
- 15 mg capsules
- 22.5 mg capsules
- 30 mg capsules
Typical Dosing
- The usual starting dose for adults is 15 mg taken once at bedtime.
- In some cases, the dose may be reduced to 7.5 mg or increased to 30 mg based on the patient's response.
- Restoril is generally prescribed for 7 to 10 days, as it is meant for short-term use only.
Typical Dosing
FDA Approved Indications
- Short-term treatment of insomnia, particularly when difficulty falling or staying asleep is the primary complaint.
Who Shouldn't Take Restoril?
- Known hypersensitivity to temazepam or other benzodiazepines.
- Pregnancy, as benzodiazepines may cause harm to the fetus (Restoril is classified as Pregnancy Category X).
- Severe sleep apnea or chronic respiratory insufficiency, as it can worsen breathing problems.
Advice From The Pharmacist
- Take Restoril just before bedtime, as it works quickly to help you fall asleep. Ensure you can dedicate at least 7 to 8 hours to sleep after taking the medication.
- Avoid alcohol and other central nervous system depressants, as combining these substances with Restoril can increase drowsiness and risk of side effects.
- Do not take Restoril if you are unable to sleep for a full 7 to 8 hours, as it may cause drowsiness or impair alertness the next day.
- Restoril is intended for short-term use only. Prolonged use may lead to dependence, tolerance, or withdrawal symptoms.
- Store Restoril at room temperature, away from moisture and heat.
Side Effects of Restoril
Common Side Effects
- Drowsiness or daytime drowsiness
- Dizziness
- Fatigue
- Headache
- Blurred vision
Uncommon/Severe Side Effects
- Complex sleep behaviors, such as sleepwalking, sleep driving, or eating while asleep, with no memory of the event
- Allergic reactions, including rash, itching, or swelling
- Severe mood changes, such as depression or thoughts of self-harm
- Respiratory depression, especially in individuals with breathing problems
Risks and Warnings of Restoril
- Risk of Dependence: Restoril can cause physical dependence, particularly with prolonged use. Abrupt discontinuation can lead to withdrawal symptoms such as seizures, tremors, or anxiety. Tapering the dose gradually is recommended when discontinuing the medication.
- Complex Sleep Behaviors: Restoril can cause complex behaviors, such as sleepwalking, sleep-driving, or performing other activities while not fully awake. Discontinue the medication if these behaviors occur.
- CNS Depression: Restoril can cause central nervous system (CNS) depression, leading to drowsiness, dizziness, and impaired coordination. Avoid activities that require full alertness, such as driving, until you know how the medication affects you.
Interactions with Restoril
Common Drug Interactions
- CNS depressants (e.g., alcohol, opioids, barbiturates): Combining Restoril with other CNS depressants can increase the risk of sedation, respiratory depression, and overdose.
- Antidepressants or antipsychotics: Restoril may enhance the sedative effects of these medications, leading to increased drowsiness or dizziness.
- Antihistamines: Taking antihistamines with Restoril can increase drowsiness and impair cognitive function.
Alternatives to Restoril
- Ambien (zolpidem): A non-benzodiazepine hypnotic used for short-term treatment of insomnia.
- Lunesta (eszopiclone): Another non-benzodiazepine hypnotic used to treat insomnia, which may be used for longer-term treatment.
- Trazodone: An antidepressant that is often prescribed off-label to treat insomnia, particularly for patients who cannot tolerate benzodiazepines.
- Melatonin: A natural hormone supplement that helps regulate sleep-wake cycles and is often used as a sleep aid for insomnia.
