ALPRAZolam ER

ALPRAZolam ER is FDA-approved for the treatment of:

• Generalized anxiety disorder (GAD)
• Panic disorder with or without agoraphobia

It is used to reduce the frequency and severity of panic attacks and to manage symptoms of anxiety, such as excessive worry, restlessness, and muscle tension.

ALPRAZolam ER should not be used in individuals who:

• Have a known hypersensitivity to alprazolam or other benzodiazepines
• Have acute narrow-angle glaucoma
• Are pregnant or breastfeeding, as the drug can harm the fetus or nursing infant
• Are taking potent CYP3A4 inhibitors, such as ketoconazole or itraconazole

Use with caution in patients with a history of substance abuse, depression, or respiratory conditions.

When taking ALPRAZolam ER, it is important to follow the prescribed dosing schedule and not to alter the dose without consulting your healthcare provider. Avoid consuming alcohol while taking this medication, as it can increase drowsiness and other side effects. Be cautious when driving or operating machinery until you know how the medication affects you. If you need to discontinue ALPRAZolam ER, do so gradually under your healthcare provider's supervision to avoid withdrawal symptoms. Store the medication securely to prevent misuse by others.

Common side effects of ALPRAZolam ER may include:

• Drowsiness
• Dizziness
• Fatigue
• Dry mouth
• Memory problems
• Difficulty concentrating

Serious side effects, though rare, may include:

• Respiratory depression
• Seizures (especially if stopped abruptly)
• Severe allergic reactions (e.g., rash, itching, swelling)
• Worsening of depression or suicidal thoughts

If any serious side effects occur, seek medical attention immediately.

The major risks associated with ALPRAZolam ER include the potential for abuse, dependence, and withdrawal symptoms. Long-term use can lead to tolerance, requiring higher doses to achieve the same effect. Abrupt discontinuation can cause withdrawal symptoms, including seizures. It is essential to use this medication only as prescribed and to taper off gradually under medical supervision when discontinuing. Patients with a history of substance abuse or those taking other central nervous system depressants should use ALPRAZolam ER with caution.

Alprazolam ER can interact with several medications, including:

• Other central nervous system depressants, such as opioids, alcohol, and barbiturates, which can increase the risk of respiratory depression
• CYP3A4 inhibitors, such as Ketoconazole, Itraconazole, and certain HIV medications, which can increase the levels of alprazolam in the blood
• Antidepressants and antipsychotics, which can enhance the sedative effects

It is important to inform your healthcare provider of all medications, supplements, and over-the-counter products you are taking to avoid potential interactions.

Alternative treatments for anxiety and panic disorders include other benzodiazepines, such as clonazePAM (KlonoPIN) and LORazepam (Ativan). Non-benzodiazepine options include selective serotonin reuptake inhibitors (SSRIs) like Sertraline HCl (Zoloft) and serotonin-norepinephrine reuptake inhibitors (SNRIs) like Venlafaxine HCl (Effexor). Cognitive-behavioral therapy (CBT) and lifestyle modifications may also be effective in managing symptoms. Discuss these options with your healthcare provider to find the best fit for your treatment plan.