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Zoloft
Zoloft, also known as Sertraline, is a type of medication known as a selective serotonin reuptake inhibitor (SSRI). It's primarily used to treat mental health disorders like depression, anxiety, obsessivecompulsive disorder (OCD), and posttraumatic stress disorder (PTSD). Some common side effects include dry mouth, upset stomach, diarrhea, sleep problems, and weight changes, but your doctor will always balance these with the potential benefits.
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Frequently Asked Questions
Can I drink alcohol while on Zoloft?
Technically you can, but it's usually not recommended. Alcohol can make the side effects of Zoloft worse.
Can I drink coffee while taking Zoloft?
It's okay to drink some coffee while taking Zoloft, but too much caffeine can increase side effects like jitteriness and nervousness.
Can I stop taking Zoloft if I feel better?
It's important not to stop taking Zoloft without your doctor's approval. Stopping suddenly can lead to withdrawal symptoms.
I am gaining weight on Zoloft, is this normal?
Some people do gain weight while on Zoloft. It's a good idea to discuss this with your doctor if this concerns you.
I missed a dose of Zoloft, what should I do?
If it?s close to the time for your next dose, then skip the missed dose. If not, take it as soon as possible. But don't double up doses!
Will Zoloft affect my sexual drive?
Some people do experience changes in libido while on Zoloft. If this bothers you, it's worth bringing up with your doctor.
Comprehensive Drug Guide
How Does Zoloft Work?
Zoloft is a potent and specific inhibitor of neuronal serotonin reuptake. It enhances serotonin activity in the brain and helps restore chemical balance, reducing the symptoms of mental health disorders.
What is Zoloft Used For?
FDA indications: Zoloft is used to treat mental health disorders like depression, panic disorder, obsessivecompulsive disorder, posttraumatic stress disorder, social phobia, and a severe form of premenstrual syndrome (PMDD).
Offlabel uses: It has also been used for the offlabel treatment of eating disorders and premature ejaculation.
Common Dosages
Tablets: 25 mg, 50 mg, 100 mg
Oral solution: 20 mg/mL
Typical Dosing
FDA Approved Indications
- For depression and OCD: Typically starts at 50 mg once daily, but may be increased up to a maximum of 200 mg per day.
- For Panic disorder, PTSD, and social phobia: Doses usually start at 25 mg once daily and are later increased to 50200 mg daily.
- For PMDD: Daily dosing maybe 50150 mg, or occasional dosing in the latter half of the menstrual cycle is also common.
Who Shouldn't Take Zoloft?
- Have an allergy to Zoloft or any of its components.
- Are taking or have recently taken monoamine oxidase inhibitors (MAOIs) or Pimozide.
- Suffer from angleclosure glaucoma.
- Have liver or kidney disease.
- Have heart problems.
- Are pregnant, planning to become pregnant, or breastfeeding (unless recommended by the doctor).
- Have mental health issues like bipolar disorder (unless recommended by your doctor).
- Have seizures or a history of seizures.
- Have a history of bleeding disorders.
Advice From The Pharmacist
- Drink a good amount of water as Zoloft can lead to a dry mouth.
- Regular meals can help prevent an upset stomach.
- It is better to take this medicine once daily in the morning or evening, but try to take it at the same time each day.
- Don?t stop taking Zoloft suddenly as it can lead to withdrawal symptoms. Talk to your doctor about tapering the dose.
- If you experience sleep issues, try taking Zoloft in the morning.
- It can take a few weeks for the full benefits of Zoloft to kick in, and it's crucial to keep your doctor's appointments
Side Effects of Zoloft
Common Side Effects
- You might experience an upset stomach, diarrhea, dry mouth, or a change in appetite.
- You might experience sleep issues like insomnia or drowsiness.
- Weight changes are also common, either loss or gain.
Uncommon/Severe Side Effects
- Rare side effects:
- In rare cases, you might have an allergic reaction to Zoloft look out for difficulty breathing, rash, or swelling on your face or throat.
- You might experience bleeding or bruising.
- If you have any thoughts about suicide or experience worsening of your depression or anxiety symptoms, reach out to a mental health professional immediately.
Risks and Warnings of Zoloft
- If you are taking monoamine oxidase inhibitors (MAOIs) or Pimozide, don't use Zoloft as it can lead to a potentially fatal drug interaction.
- If you have a history of bipolar disorder, Zoloft may potentially trigger manic episodes consult your doctor.
- If you?re planning to become pregnant, already are, or are breastfeeding, it?s essential to consult a healthcare provider as Zoloft may potentially affect the infant.
- Zoloft may potentially increase the risk of suicidal thoughts in children and young adults always monitor them closely.
- Zoloft is associated with a bleeding risk, particularly if you?re taking other medication like aspirin or NSAIDs.
Interactions with Zoloft
Common Drug Interactions
- MAOIs and Pimozide
- Aspirin
- NSAIDs like ibuprofen or naproxen
- Diuretics
- Sedatives or sleepinducing medications
- Other antidepressants
Alternatives to Zoloft
- Fluoxetine
- Citalopram
- Escitalopram
- Paroxetine
- Venlafaxine
- Desvenlafaxine
- Duloxetine
