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Ketoconazole
Ketoconazole is an antifungal medication that works by stopping the growth of fungi. It's classified as an azole antifungal and is typically used to treat a variety of fungal infections including certain kinds of serious fungal infections, yeast infections, or seborrheic dermatitis. Possible side effects may include nausea, vomiting, or abdominal pain, but your healthcare provider will ensure that its benefits outweigh these issues.
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Frequently Asked Questions
Can I stop taking Ketoconazole once the symptoms disappear?
It is important to complete the prescribed course of medicine even if your symptoms disappear. Stopping the medication too soon may allow the fungus to continue to grow and the infection might return.
Can I stop taking Ketoconazole without finishing the course?
It is not advisable to stop this medication abruptly unless your doctor recommends it. Indeed, the fungal infection might come back if you stop the medication too soon.
Can I take Ketoconazole if I am breastfeeding?
Yes, but it's always a good idea to discuss with your doctor first, as small amounts may pass into breast milk.
Does Ketoconazole have any interactions with grapefruit juice?
Yes, grapefruit juice can increase the amount of Ketoconazole that your body absorbs. It is advisable to avoid consuming grapefruit while on this medication.
Does Ketoconazole interfere with other medications?
Ketoconazole can interact with many different medications, including certain anticoagulants and cholesterol medications. Always inform your healthcare provider about all other medications you're taking.
I missed a dose of Ketoconazole. What should I do?
Take the missed dose as soon as you remember, unless it's almost time for your next dose. Do not take two doses to make up for the missed one.
Is it safe to drink alcohol while on Ketoconazole?
Alcohol should be consumed in moderation while taking Ketoconazole, as it may increase the chance of liver damage.
Is Ketoconazole safe during pregnancy?
Ketoconazole should be used during pregnancy only if the potential benefits justify the potential risks. Always consult your healthcare provider.
What should I do if I miss a dose?
If it is close to the time for your next dose, skip the missed dose and go back to your normal time. If it is still early, consume the missed dose as soon as possible.
Comprehensive Drug Guide
How Does Ketoconazole Work?
Ketoconazole works by inhibiting the synthesis of ergosterol, a key component of the fungal cell membrane, leading to increased cellular permeability and leakage of essential components.
What is Ketoconazole Used For?
FDA indications: Ketoconazole is used to treat a wide variety of fungal infections including blastomycosis, coccidioidomycosis, histoplasmosis, chromomycosis, and paracoccidioidomycosis.
Offlabel uses: It may be recommended by a healthcare provider for the treatment of advanced prostate cancer or Cushing syndrome.
Common Dosages
Tablets: 200mg
Topical shampoo: 1%, 2%
Typical Dosing
FDA Approved Indications
- Fungal infections the usual recommended dose is 200mg to 400mg daily.
Off-Label Uses
- Dosing depends upon the severity of the condition under treatment and will be determined by the healthcare provider.
Who Shouldn't Take Ketoconazole?
- Anyone who has had an allergic reaction or severe side effects to ketoconazole should avoid using this medication. It should also not be used in patients with severe liver disease or those taking certain medications as this may increase the risk of severe liver damage.
Advice From The Pharmacist
- Take Ketoconazole exactly as prescribed by your healthcare provider. Do not stop taking the medication without your doctor's advice, even if you start to feel better. The medication is taken orally and should be taken along with food. Continually monitor for any side effects.
Side Effects of Ketoconazole
Common Side Effects
- You may experience nausea, vomiting, or stomach discomfort.
Uncommon/Severe Side Effects
- ncommon side effects:
- Headache, dizziness, or changes in menstrual periods for women may occur.
- Rare side effects:
- In some instances, Ketoconazole may cause serious liver damage leading to symptoms such as fatigue, loss of appetite, and yellowing of the skin or eyes.
Risks and Warnings of Ketoconazole
- Patients with active or chronic liver disease should not use this medication due to its potential for liver damage. Ketoconazole has also been known to cause adrenal insufficiency, so if you have adrenal problems, you should speak with your healthcare provider before using this medication.
Interactions with Ketoconazole
Common Drug Interactions
- Anticoagulants
- Certain antiretrovirals
- Certain cholesterol medications
Alternatives to Ketoconazole
- Fluconazole
- Clotrimazole
- Miconazole
- Itraconazole
