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Oxazepam

Oxazepam is a medication belonging to the benzodiazepine class, primarily used for the treatment of anxiety disorders and insomnia. It is also prescribed for the management of alcohol withdrawal symptoms. Oxazepam helps to produce a calming effect by enhancing the activity of certain neurotransmitters in the brain.



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Frequently Asked Questions

How quickly does Oxazepam work?
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Oxazepam typically begins to take effect within 30 minutes to 1 hour after administration.

Can I take Oxazepam with food?
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Yes, Oxazepam can be taken with or without food.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while using Oxazepam?
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There are no specific dietary restrictions while using Oxazepam, but avoiding alcohol is recommended.

Is Oxazepam safe during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using Oxazepam during these periods.

Comprehensive Drug Guide

How Does Oxazepam Work?

Oxazepam works by binding to the GABA-A receptor in the brain, enhancing the inhibitory effects of gamma-aminobutyric acid (GABA). This action leads to increased neuronal inhibition, producing a calming effect, reducing anxiety, and promoting sleep.



Common Dosages

  • Tablets: Common strengths include 10 mg, 15 mg, and 30 mg.

Typical Dosing

  • For anxiety: The usual starting dose is 10 mg to 30 mg taken orally three to four times daily, depending on the severity of symptoms.
  • For insomnia: The typical dose is 15 mg to 30 mg taken before bedtime.


Typical Dosing

FDA Approved Indications

  • Anxiety Disorders: for the short-term management of anxiety.
  • Insomnia: for the short-term treatment of sleep disturbances.
  • Alcohol Withdrawal: for the management of symptoms associated with alcohol withdrawal.


Who Shouldn't Take Oxazepam?

  • Known hypersensitivity to oxazepam or any component of the formulation.
  • Severe respiratory insufficiency.
  • Sleep apnea syndrome.


Advice From The Pharmacist

  • Take Oxazepam exactly as prescribed, and do not stop taking it abruptly without consulting your healthcare provider, as this may lead to withdrawal symptoms.
  • Avoid alcohol while taking oxazepam, as it can enhance sedation and increase the risk of respiratory depression.
  • Be aware of the potential for drowsiness; use caution when driving or operating heavy machinery.


Side Effects of Oxazepam

Common Side Effects

  • Drowsiness
  • Dizziness
  • Fatigue
  • Confusion
  • Dry mouth


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Respiratory depression
  • Dependence and withdrawal symptoms.


Risks and Warnings of Oxazepam

  • Dependence and Withdrawal: Prolonged use can lead to physical dependence; dosage should be carefully managed and gradually reduced if discontinuing.
  • Cognitive Impairment: May impair cognitive and motor functions, especially in older adults.


Interactions with Oxazepam

Common Drug Interactions

  • CNS Depressants: Use with caution when combined with other central nervous system depressants, such as alcohol, opioids, or muscle relaxants, as this may enhance sedative effects.
  • Antidepressants: Some antidepressants may interact with benzodiazepines; consult your healthcare provider for specific recommendations.


Alternatives to Oxazepam

  • Other Anxiolytics: Such as buspirone or other benzodiazepines for managing anxiety.
  • Non-benzodiazepine Sleep Aids: Such as zolpidem for insomnia.