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NiHowdy > Drug Classes > Insulin Analogs

Browse Medications by Drug Class: Insulin Analogs

Author

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed By

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Updated Jan 24, 2025

Published Jan 15, 2025

Fact checked Fact checked

What are Insulin Analogs?

Insulin analogs are synthetic forms of insulin designed to mimic the body's natural insulin while providing improved pharmacokinetic profiles. These medications are used to manage blood glucose levels in individuals with diabetes, including type 1 diabetes, type 2 diabetes, and gestational diabetes. Insulin analogs are engineered to act faster or last longer than regular human insulin, allowing for better glycemic control and flexibility in treatment regimens. A unique characteristic of insulin analogs is their ability to closely replicate the body's natural insulin response, reducing the risk of hypoglycemia and improving overall glucose management. NiHowdy ensures affordable access to these essential therapies, helping patients achieve optimal diabetes control.

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List of drugs in Insulin Analogs

Drug NameMore InformationNiHowdy Prices & Bitcoin Rebate
AdmelogAdmelog InformationAdmelog Pricing
Admelog SoloStarAdmelog SoloStar InformationAdmelog SoloStar Pricing
ApidraApidra InformationApidra Pricing
Apidra SoloStarApidra SoloStar InformationApidra SoloStar Pricing
Basaglar KwikPenBasaglar KwikPen InformationBasaglar KwikPen Pricing
Basaglar Tempo PenBasaglar Tempo Pen InformationBasaglar Tempo Pen Pricing
FiaspFiasp InformationFiasp Pricing
Fiasp FlexTouchFiasp FlexTouch InformationFiasp FlexTouch Pricing
Fiasp PenFillFiasp PenFill InformationFiasp PenFill Pricing
HumaLOGHumaLOG InformationHumaLOG Pricing
HumaLOG Junior KwikPenHumaLOG Junior KwikPen InformationHumaLOG Junior KwikPen Pricing
HumaLOG KwikPenHumaLOG KwikPen InformationHumaLOG KwikPen Pricing
HumaLOG Mix 50/50HumaLOG Mix 50/50 InformationHumaLOG Mix 50/50 Pricing
HumaLOG Mix 50/50 KwikPenHumaLOG Mix 50/50 KwikPen InformationHumaLOG Mix 50/50 KwikPen Pricing
HumaLOG Mix 75/25HumaLOG Mix 75/25 InformationHumaLOG Mix 75/25 Pricing
HumaLOG Mix 75/25 KwikPenHumaLOG Mix 75/25 KwikPen InformationHumaLOG Mix 75/25 KwikPen Pricing
HumaLOG Tempo PenHumaLOG Tempo Pen InformationHumaLOG Tempo Pen Pricing
HumuLIN R U-500 (CONCENTRATED)HumuLIN R U-500 (CONCENTRATED) InformationHumuLIN R U-500 (CONCENTRATED) Pricing
HumuLIN R U-500 KwikPenHumuLIN R U-500 KwikPen InformationHumuLIN R U-500 KwikPen Pricing
Insulin Asp Prot & Asp FlexPenInsulin Asp Prot & Asp FlexPen InformationInsulin Asp Prot & Asp FlexPen Pricing
Insulin AspartInsulin Aspart InformationInsulin Aspart Pricing
Insulin Aspart FlexPenInsulin Aspart FlexPen InformationInsulin Aspart FlexPen Pricing
Insulin Aspart PenFillInsulin Aspart PenFill InformationInsulin Aspart PenFill Pricing
Insulin Aspart Prot & AspartInsulin Aspart Prot & Aspart InformationInsulin Aspart Prot & Aspart Pricing
Insulin DegludecInsulin Degludec InformationInsulin Degludec Pricing
Insulin Degludec FlexTouchInsulin Degludec FlexTouch InformationInsulin Degludec FlexTouch Pricing
Insulin GlargineInsulin Glargine InformationInsulin Glargine Pricing
Insulin Glargine SolostarInsulin Glargine Solostar InformationInsulin Glargine Solostar Pricing
Insulin Glargine-yfgnInsulin Glargine-yfgn InformationInsulin Glargine-yfgn Pricing
Insulin LisproInsulin Lispro InformationInsulin Lispro Pricing
Insulin Lispro (1 Unit Dial)Insulin Lispro (1 Unit Dial) InformationInsulin Lispro (1 Unit Dial) Pricing
Insulin Lispro Junior KwikPenInsulin Lispro Junior KwikPen InformationInsulin Lispro Junior KwikPen Pricing
Insulin Lispro Prot & LisproInsulin Lispro Prot & Lispro InformationInsulin Lispro Prot & Lispro Pricing
LantusLantus InformationLantus Pricing
Lantus SoloStarLantus SoloStar InformationLantus SoloStar Pricing
LevemirLevemir InformationLevemir Pricing
Levemir FlexPenLevemir FlexPen InformationLevemir FlexPen Pricing
Levemir FlexTouchLevemir FlexTouch InformationLevemir FlexTouch Pricing
LyumjevLyumjev InformationLyumjev Pricing
Lyumjev KwikPenLyumjev KwikPen InformationLyumjev KwikPen Pricing
Lyumjev Tempo PenLyumjev Tempo Pen InformationLyumjev Tempo Pen Pricing
NovoLOGNovoLOG InformationNovoLOG Pricing
NovoLOG 70/30 FlexPen ReliOnNovoLOG 70/30 FlexPen ReliOn InformationNovoLOG 70/30 FlexPen ReliOn Pricing
NovoLOG FlexPenNovoLOG FlexPen InformationNovoLOG FlexPen Pricing
NovoLOG FlexPen ReliOnNovoLOG FlexPen ReliOn InformationNovoLOG FlexPen ReliOn Pricing
NovoLOG Mix 70/30NovoLOG Mix 70/30 InformationNovoLOG Mix 70/30 Pricing
NovoLOG Mix 70/30 FlexPenNovoLOG Mix 70/30 FlexPen InformationNovoLOG Mix 70/30 FlexPen Pricing
NovoLOG Mix 70/30 ReliOnNovoLOG Mix 70/30 ReliOn InformationNovoLOG Mix 70/30 ReliOn Pricing
NovoLOG PenFillNovoLOG PenFill InformationNovoLOG PenFill Pricing
NovoLOG ReliOnNovoLOG ReliOn InformationNovoLOG ReliOn Pricing
Rezvoglar KwikPenRezvoglar KwikPen InformationRezvoglar KwikPen Pricing
SemgleeSemglee InformationSemglee Pricing
Semglee (yfgn)Semglee (yfgn) InformationSemglee (yfgn) Pricing
SoliquaSoliqua InformationSoliqua Pricing
SymlinPen 120SymlinPen 120 InformationSymlinPen 120 Pricing
SymlinPen 60SymlinPen 60 InformationSymlinPen 60 Pricing
Toujeo Max SoloStarToujeo Max SoloStar InformationToujeo Max SoloStar Pricing
Toujeo SoloStarToujeo SoloStar InformationToujeo SoloStar Pricing
TresibaTresiba InformationTresiba Pricing
Tresiba FlexTouchTresiba FlexTouch InformationTresiba FlexTouch Pricing
XultophyXultophy InformationXultophy Pricing

Brief history about Insulin Analogs?

Insulin analogs were developed in the late 20th century to overcome limitations of regular human insulin. The first rapid-acting analog, lispro, was approved in the mid-1990s, followed by long-acting analogs such as glargine and detemir. These innovations provided significant advancements in diabetes care, offering more predictable glucose-lowering effects and reducing the burden of frequent blood sugar monitoring. Modern analogs, including ultra-rapid and ultra-long-acting options, continue to improve flexibility and convenience for patients. NiHowdy simplifies access to these cutting-edge therapies, ensuring affordability for individuals managing diabetes.

How do Insulin Analogs work?

Insulin analogs work by binding to insulin receptors on the surface of cells, facilitating the uptake of glucose from the bloodstream into tissues like muscles and fat. This process helps lower blood glucose levels and provides the energy cells need to function. ^ Rapid-acting analogs (e.g., lispro, aspart) are designed to act quickly after meals, mimicking the body's natural insulin release in response to food intake. ^ Long-acting analogs (e.g., glargine, detemir) provide a steady and prolonged insulin effect, mimicking basal insulin secretion to manage glucose levels throughout the day and night. These tailored profiles help maintain glucose balance, reduce the risk of complications, and improve overall glycemic control. NiHowdy ensures patients can access these advanced therapies affordably and conveniently.

What are Insulin Analogs used to treat?

Type 1 Diabetes

Insulin analogs are essential for managing type 1 diabetes, where the pancreas produces little to no insulin. These medications provide both basal (long-acting) insulin to maintain steady blood sugar levels throughout the day and bolus (rapid-acting) insulin to manage spikes after meals. Rapid-acting analogs, such as lispro and aspart, mimic the body's natural insulin response to food, preventing dangerous post-meal glucose surges. Long-acting analogs, such as glargine and detemir, ensure consistent blood sugar control overnight and between meals, reducing the risk of long-term complications like nerve damage, kidney disease, and cardiovascular issues.

Type 2 Diabetes

In type 2 diabetes, where the body becomes resistant to insulin or produces insufficient amounts, insulin analogs are used when other treatments, such as oral medications or lifestyle changes, are not enough. Long-acting insulin analogs stabilize blood sugar levels throughout the day and night, while rapid-acting analogs address post-meal glucose spikes. This dual approach helps prevent complications such as neuropathy, retinopathy, and cardiovascular disease. Insulin analogs are particularly effective for patients requiring precise glucose control, such as those with advanced diabetes or additional health conditions.

Gestational Diabetes

Insulin analogs are the preferred treatment for gestational diabetes because they are safe for both the mother and the developing baby. These medications help maintain target blood sugar levels, reducing the risk of complications such as preeclampsia, preterm birth, and macrosomia (excessively large babies). Rapid-acting analogs control blood sugar after meals, while long-acting analogs maintain steady glucose levels between meals and overnight. Proper glycemic control during pregnancy ensures healthier outcomes for both the mother and child.

Who should consider Insulin Analogs medications?

Adults

Adults with type 1 or type 2 diabetes benefit greatly from insulin analogs due to their flexibility and efficacy in managing blood sugar levels. For those with type 1 diabetes, a combination of rapid-acting and long-acting analogs provides comprehensive control of blood glucose throughout the day. Adults with type 2 diabetes who struggle to achieve glycemic targets with oral medications may also require insulin analogs. Long-acting analogs simplify regimens by reducing the need for multiple daily injections, while rapid-acting analogs address specific post-meal glucose challenges. These medications are especially suitable for adults with busy lifestyles, as they allow for greater flexibility in meal timing and activity levels.

Children

Children with type 1 diabetes rely on insulin analogs to achieve tight blood sugar control during critical growth and developmental stages. Rapid-acting analogs prevent dangerous glucose spikes after meals, while long-acting analogs maintain stable glucose levels overnight and between meals. Insulin analogs offer predictable action profiles, reducing the risk of severe hypoglycemia and enabling better participation in daily activities, including sports and school. For children with type 2 diabetes, insulin analogs may be used when lifestyle modifications and oral medications fail to control blood sugar. Pediatric-specific dosing and formulations make these medications safe and effective for young patients.

Seniors

Seniors with diabetes benefit from the safety and efficacy of insulin analogs, particularly those with long-acting properties, which reduce the risk of hypoglycemia?a common concern in this age group. Simplified dosing schedules offered by long-acting analogs like glargine or degludec are especially advantageous for older adults who may have difficulty managing complex regimens. Rapid-acting analogs can be added to address post-meal glucose spikes when necessary. Healthcare providers carefully monitor seniors for age-related changes in metabolism, kidney function, and the potential for drug interactions, ensuring optimal dosing and safety. Seniors with additional comorbidities, such as cardiovascular disease or cognitive decline, also benefit from the precise glucose control provided by insulin analogs, improving overall health outcomes.

Are Insulin Analogs safe?

Insulin analogs are generally safe when used as prescribed. Common side effects include hypoglycemia, weight gain, and mild injection site reactions such as redness or swelling. Rare but serious risks include severe hypoglycemia or allergic reactions. Proper dosing, regular blood sugar monitoring, and adherence to the prescribed regimen minimize these risks. Regular follow-ups with a healthcare provider ensure the safe and effective use of insulin analogs.

Can I take Insulin Analogs during pregnancy?

Insulin analogs, such as aspart and glargine, are considered safe and effective during pregnancy for managing gestational diabetes or pre-existing diabetes. These medications help maintain optimal blood sugar levels, reducing the risk of complications for both mother and baby. Patients should work closely with their healthcare provider to develop an appropriate treatment plan.

Are Insulin Analogs safe to take while lactating?

Insulin analogs are safe to use while breastfeeding, as they do not pass into breast milk in significant amounts. These medications allow lactating individuals with diabetes to manage their blood sugar levels effectively without compromising the baby's health.

Are Insulin Analogs controlled substances?

Insulin analogs are not classified as controlled substances. However, they require a prescription and proper medical supervision to ensure safe and effective use, particularly in managing blood sugar levels.

Side effects of Insulin Analogs?

Insulin analogs are generally well-tolerated, but they may cause side effects. The most common side effect is hypoglycemia, which occurs when blood sugar levels drop too low. Symptoms include shakiness, sweating, confusion, and, in severe cases, unconsciousness. Proper meal timing and dose adjustments help reduce this risk. Other common side effects include mild weight gain and injection site reactions, such as redness, swelling, or itching. These are usually temporary and resolve with continued use. Rare but serious side effects include severe allergic reactions, characterized by difficulty breathing or swelling, requiring immediate medical attention. Patients should work closely with their healthcare provider to optimize dosing and minimize side effects. Regular follow-ups and blood sugar monitoring ensure safe and effective use of insulin analogs.

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Cost considerations and insurance coverage for Insulin Analogs

The cost of insulin analogs varies depending on the specific medication and formulation. Newer analogs like glargine and aspart tend to be more expensive than regular insulin. However, most insurance plans cover insulin analogs for diabetes management. Manufacturer assistance programs and discount cards can help reduce out-of-pocket costs. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these life-saving treatments remain accessible and cost-effective.

How do I get rebates on Insulin Analogs?

NiHowdy's Bitcoin rebate program for insulin analog prescriptions provides patients with a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing diabetes both affordable and rewarding, improving access to life-changing treatments while building long-term value.

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