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Levemir
Levemir, the brand name for insulin detemir, is a long-acting insulin used to help control blood sugar levels in individuals with type 1 and type 2 diabetes. Levemir provides steady blood sugar control for up to 24 hours, helping to prevent both high (hyperglycemia) and low (hypoglycemia) blood sugar levels. It is often used in combination with short-acting insulin or other diabetes medications to maintain stable glucose levels throughout the day and night. Levemir is typically administered once or twice daily, depending on individual needs.
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Frequently Asked Questions
What should I do if I miss a dose of Levemir?
If you miss a dose, contact your healthcare provider for advice. Do not double up on doses to make up for a missed one.
Can I take Levemir with other insulins?
Yes, Levemir is often used in combination with rapid-acting insulin to control mealtime blood sugar levels. However, it should not be mixed with other insulins in the same syringe.
How long does Levemir last?
Levemir provides steady blood sugar control for up to 24 hours, depending on the individual and the dose.
What happens if I experience low blood sugar while taking Levemir?
If you experience symptoms of hypoglycemia (dizziness, sweating, shakiness), consume a fast-acting source of sugar (such as juice or candy) and monitor your blood sugar levels. Seek medical attention if you experience severe hypoglycemia.
Can Levemir cause weight gain?
Yes, weight gain is a possible side effect of insulin therapy, including Levemir. It is important to maintain a healthy diet and exercise plan while managing your diabetes.
Comprehensive Drug Guide
How Does Levemir Work?
Levemir works by mimicking the natural hormone insulin, which regulates blood sugar levels. Once injected, insulin detemir is slowly absorbed into the bloodstream, providing steady insulin levels for up to 24 hours. Unlike rapid-acting insulins, which work quickly to control blood sugar spikes after meals, Levemir helps control blood sugar between meals and overnight, reducing the risk of hyperglycemia and maintaining overall glucose control.
Common Dosages
Levemir is available in:
- 100 units/mL in 10 mL vials (for use with syringes)
- Levemir FlexTouch pre-filled pens, containing 3 mL of insulin (300 units total)
The dosage of Levemir is individualized based on factors such as blood sugar levels, weight, and other diabetes medications.
Typical Dosing
For adults and children with type 1 diabetes:
- Once daily or twice daily injection depending on individual needs and blood sugar patterns.
- Typically combined with rapid-acting insulin to manage mealtime blood sugar levels.
For adults with type 2 diabetes:
- Once daily injection, often used alone or in combination with other diabetes medications such as oral hypoglycemics.
Your healthcare provider will determine the appropriate dose based on your blood sugar levels, and adjustments may be made as needed.
Typical Dosing
FDA Approved Indications
- Type 1 diabetes in adults and children as young as 2 years old, to provide basal insulin for controlling blood sugar.
- Type 2 diabetes in adults, often used alone or in combination with other diabetes medications to manage blood sugar.
Who Shouldn't Take Levemir?
- Allergy to insulin detemir or any other ingredient in the formulation.
- During episodes of hypoglycemia (low blood sugar).
Advice From The Pharmacist
- Levemir should be injected once or twice daily, depending on your healthcare provider's instructions.
- Administer the injection subcutaneously (under the skin) in the abdomen, thigh, or upper arm, and rotate injection sites to avoid irritation.
- Do not mix Levemir with other insulins or solutions in the same syringe.
- If you miss a dose, contact your healthcare provider for advice.
- Always store unopened vials or pens in the refrigerator, but once opened, they can be kept at room temperature for up to 42 days.
- Monitor your blood sugar levels regularly, especially when starting Levemir or adjusting your dose, to avoid hypoglycemia or hyperglycemia.
Side Effects of Levemir
Common Side Effects
- Low blood sugar (hypoglycemia), which may cause symptoms such as dizziness, sweating, shakiness, or confusion.
- Injection site reactions, such as redness, swelling, or itching.
- Weight gain, which can occur with insulin use.
Uncommon/Severe Side Effects
- Severe hypoglycemia, which can cause fainting, seizures, or loss of consciousness.
- Allergic reactions, such as swelling or trouble breathing.
Risks and Warnings of Levemir
- Levemir can cause hypoglycemia (low blood sugar), especially if you take too much insulin, skip meals, or engage in intense physical activity.
- Monitor your blood sugar regularly and be aware of the symptoms of hypoglycemia.
- If you experience low blood sugar, consume a fast-acting source of sugar (such as juice or glucose tablets) and recheck your blood sugar levels.
- Be cautious when using Levemir if you have liver or kidney disease, as these conditions can affect how your body processes insulin.
- Always carry a form of fast-acting sugar with you in case of a low blood sugar emergency.
Interactions with Levemir
Common Drug Interactions
- Oral diabetes medications or other insulins, which may affect blood sugar levels.
- Beta-blockers, which can mask the symptoms of low blood sugar.
- Steroids, diuretics, or birth control pills, which may raise blood sugar levels.
Alternatives to Levemir
- Lantus (insulin glargine)
- Tresiba (insulin degludec)
- Toujeo (insulin glargine)
