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Insulin Degludec
Insulin Degludec is an ultra-long-acting type of insulin used to control high blood sugar in adults with diabetes mellitus. It works by replacing the insulin that the body would normally produce, thereby helping to absorb sugar in the body for energy. Common side effects may include hypoglycemia (low blood sugar), allergic reactions, injection site reactions, and weight gain, but the benefits typically outweigh these.
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Frequently Asked Questions
Will Insulin Degludec make me gain weight?
Yes, weight gain can be a side effect of Insulin Degludec. It's important to maintain a balanced diet and exercise regularly to help manage your weight while on this medication.
What should I do if I missed a dose of Insulin Degludec?
If it s almost time for the next dose, skip the missed dose. However, if it's still a long way off, you can take the missed dose. Next time, try to ensure you take it at the same time every day to avoid missing a dose.
Does Insulin Degludec mix with other types of insulin?
Never mix or dilute Insulin Degludec with any other insulin unless specifically instructed by your healthcare provider.
Can I drink alcohol while using Insulin Degludec?
Alcohol can affect your blood sugar levels and how insulin works, it s best to limit alcohol intake while using Insulin Degludec.
Is Insulin Degludec safe during pregnancy?
Insulin Degludec is classified as Pregnancy Category C. This means that caution is advised and the benefits of the medication should be weighed against the potential risks. If you are pregnant or planning to become pregnant, consult your healthcare provider.
Comprehensive Drug Guide
How Does Insulin Degludec Work?
Insulin Degludec is an ultra-long-acting, man-made version of human insulin. It works by replacing the insulin that is normally produced by the body and helps the body utilize sugar for energy. It also stops the liver from releasing more sugar.
What is Insulin Degludec Used For?
FDA indications: Insulin Degludec is intended to cover basal insulin requirements in adults with both type 1 and type 2 diabetes and in children with type 1 diabetes.
Off-label uses: There are currently no recognized off-label uses for Insulin Degludec.
Common Dosages
Injection: 100 units/mL, 200 units/mL
Typical Dosing
FDA Approved Indications
- Insulin Degludec is typically dosed once daily, at the same time each day. The dose is determined by the healthcare provider based on individual needs and the types of diabetes.
Who Shouldn't Take Insulin Degludec?
- Those allergic to Insulin Degludec or any of its ingredients.
- People experience hypoglycemia (low blood sugar), without the presence of slow-acting carbohydrates or a meal soon after the administration.
Advice From The Pharmacist
- Regularly monitor your blood glucose levels, as directed by your healthcare provider.
- Insulin Degludec is usually given once a day, at the same time each day.
- Inject the insulin under the skin, do not inject it into muscles or veins.
- Immediately eat a meal or snack containing carbohydrates after administering short- or rapid-acting mealtime insulin to prevent hypoglycemia.
- Store unused pens in the refrigerator, never freeze. Opened pens can be stored at room temperature.
Side Effects of Insulin Degludec
Common Side Effects
- Injection site reactions (pain, redness, irritation) may occur.
Uncommon/Severe Side Effects
- Rare side effects:
- Changes in skin thickness at the injection site.
- Muscle cramps have been reported.
- Severe side effects:
- Serious low blood sugar (hypoglycemia) can happen.
- If you notice sweating, shaking, a fast heartbeat, or blurred vision, handle it promptly. Rarely, a severe allergic reaction to this drug may occur, needing immediate medical intervention.
Risks and Warnings of Insulin Degludec
- Insulin Degludec should not be used during episodes of hypoglycemia.
- It should be used with caution in patients with kidney or liver disease, heart failure, or a history of hypokalemia.
- Do not mix or dilute Insulin Degludec with any other insulin products or liquids.
- Always check insulin labels before administration.
Interactions with Insulin Degludec
Common Drug Interactions
- Beta-blockers
- Thiazides
- Corticosteroids
- Thyroid hormones
Alternatives to Insulin Degludec
- Insulin glargine
- Insulin detemir
- Insulin NPH
- Insulin regular
