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Lantus
Lantus, the brand name for insulin glargine, is a long-acting insulin used to help control blood sugar levels in individuals with type 1 and type 2 diabetes. It is typically administered once daily and provides a steady release of insulin over 24 hours to help manage blood sugar levels throughout the day and night. Lantus works by replacing the insulin that your body either doesn't produce or doesn't use efficiently, helping prevent high blood sugar (hyperglycemia) and, in some cases, avoiding the dangerous lows (hypoglycemia) associated with diabetes management.
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Frequently Asked Questions
What should I do if I miss a dose of Lantus?
If you miss a dose, contact your healthcare provider for advice on what to do. Do not double up on doses to make up for a missed one.
Can I take Lantus with other insulins?
Yes, Lantus is often used in combination with rapid-acting insulins (for meals) in individuals with type 1 diabetes. It should not be mixed with other insulins in the same syringe.
How long does Lantus last?
Lantus provides up to 24-hour blood sugar control, making it a long-acting insulin that only needs to be taken once a day.
What happens if I experience low blood sugar while taking Lantus?
If you experience symptoms of hypoglycemia (dizziness, sweating, shakiness), consume a fast-acting source of sugar (juice, candy, glucose tablets) and monitor your blood sugar levels. Contact your healthcare provider if you have frequent low blood sugar episodes.
Can Lantus cause weight gain?
Yes, weight gain is a possible side effect of insulin therapy, including Lantus, as insulin helps your body store glucose, which can lead to increased fat storage.
Comprehensive Drug Guide
How Does Lantus Work?
Lantus works by mimicking the natural hormone insulin, which regulates blood sugar. Once injected, insulin glargine is slowly released over a 24-hour period, providing steady, long-lasting blood sugar control. Unlike rapid-acting insulin, Lantus doesn't work immediately after injection; instead, it helps control blood sugar between meals and overnight by preventing the liver from releasing too much glucose.
Common Dosages
Lantus is available in:
- 100 units/mL in 10 mL vials (for use with syringes)
- Lantus SoloStar pre-filled pens with 3 mL of insulin (300 units total)
The dose of Lantus is individualized based on factors like blood sugar levels, weight, and how your body responds to insulin.
Typical Dosing
- Lantus is usually injected once daily, at the same time each day, to provide consistent 24-hour blood sugar control. Your healthcare provider will determine the appropriate dose based on your blood sugar readings and any other diabetes medications you are using. In type 1 diabetes, Lantus is often combined with rapid-acting insulin for mealtime control.
- The initial starting dose for individuals switching from other insulin regimens or starting insulin therapy is often based on weight, and the dose may be adjusted by your healthcare provider based on your blood sugar control.
Typical Dosing
FDA Approved Indications
Lantus is FDA-approved for:
- Management of type 1 diabetes in adults and children aged 6 years and older.
- Management of type 2 diabetes in adults who require basal insulin to control their blood sugar.
Lantus is used in combination with short-acting insulin or other diabetes medications in type 1 diabetes, and it may be used alone or with other medications in type 2 diabetes.
Who Shouldn't Take Lantus?
- Allergy to insulin glargine or any ingredient in the formulation.
- During episodes of hypoglycemia (low blood sugar).
Advice From The Pharmacist
- Lantus should be injected once daily at the same time each day.
- Administer the injection subcutaneously (under the skin) in the abdomen, thigh, or upper arm, and rotate injection sites to avoid skin irritation.
- Do not mix Lantus with any other insulin or solution.
- If you miss a dose, contact your healthcare provider for guidance on how to proceed.
- Always store unopened vials or pens in the refrigerator, but once opened, they can be kept at room temperature for up to 28 days.
- Monitor your blood sugar regularly and adjust your diet, exercise, and medication as directed by your healthcare provider.
Side Effects of Lantus
Common Side Effects
- Low blood sugar (hypoglycemia), which may cause symptoms such as dizziness, sweating, shakiness, or confusion.
- Injection site reactions, such as redness, swelling, or itching.
- Weight gain.
Uncommon/Severe Side Effects
- Severe hypoglycemia, which can cause fainting, seizures, or loss of consciousness.
- Allergic reactions, such as rash, swelling, or trouble breathing.
Risks and Warnings of Lantus
- Lantus can cause hypoglycemia (low blood sugar), particularly if you take too much insulin, miss a meal, or engage in intense physical activity.
- Monitor your blood sugar regularly, especially when starting Lantus or adjusting your dose.
- If you experience hypoglycemia, consume a fast-acting source of sugar, such as juice or glucose tablets, and recheck your blood sugar levels.
- Lantus should be used with caution in individuals with liver or kidney disease, as these conditions can affect how insulin is processed. Always carry a form of fast-acting sugar with you in case of low blood sugar episodes.
Interactions with Lantus
Common Drug Interactions
- Oral diabetes medications or other insulins, which can affect blood sugar levels.
- Beta-blockers, which can mask the symptoms of low blood sugar.
- Steroids, diuretics, or birth control pills, which can increase blood sugar levels
Alternatives to Lantus
- Levemir (insulin detemir)
- Tresiba (insulin degludec)
- Toujeo (a higher-concentration form of insulin glargine)
