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Tresiba FlexTouch
Tresiba FlexTouch (insulin degludec) is a long-acting basal insulin used to improve blood sugar control in people with type 1 and type 2 diabetes mellitus. Tresiba provides steady insulin release over a period of up to 42 hours, making it one of the longest-acting insulins available. It is typically used as a once-daily injection to help manage blood glucose levels, and its flexible dosing time allows for more convenience in managing diabetes.
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Frequently Asked Questions
How long does Tresiba FlexTouch last in the body?
Tresiba provides long-lasting insulin effects for up to 42 hours, offering more flexibility with dosing times compared to other long-acting insulins.
Can I use Tresiba FlexTouch if I miss a dose?
If you miss a dose of Tresiba, take it as soon as you remember, as long as it is not too close to your next scheduled dose. Try to establish a regular routine to avoid missing doses.
Can I take Tresiba FlexTouch with other insulin types?
Yes, Tresiba can be combined with other insulin types, such as rapid-acting insulin for mealtime blood sugar control. However, this should be done under the guidance of your healthcare provider.
How should I store my Tresiba FlexTouch pen?
Unopened pens should be stored in the refrigerator. Once in use, they can be kept at room temperature and should be discarded 8 weeks after the first use.
Is Tresiba safe for children?
Yes, Tresiba is approved for use in children with type 1 diabetes who are 1 year of age or older. Always follow the dosing instructions provided by your healthcare provider.
Comprehensive Drug Guide
How Does Tresiba FlexTouch Work?
Tresiba FlexTouch works by providing a slow and steady release of insulin, helping to regulate blood glucose levels over an extended period. Insulin degludec mimics the body’s basal insulin, helping the body utilize glucose more effectively and preventing the liver from producing excess glucose. This insulin reduces blood sugar levels throughout the day and night, helping patients with diabetes maintain stable blood sugar levels.
Common Dosages
- 100 units/mL pre-filled pen: Delivers doses up to 80 units per injection.
- 200 units/mL pre-filled pen: Delivers doses up to 160 units per injection.
Typical Dosing
- The dose of Tresiba FlexTouch is individualized based on the patient’s needs. It is typically injected once daily, at any time of the day, with or without meals.
- The starting dose is usually 10 units once daily, but this may vary based on the patient's blood glucose levels and insulin requirements.
Typical Dosing
FDA Approved Indications
- Type 1 diabetes mellitus in adults and children.
- Type 2 diabetes mellitus in adults who require long-acting insulin for blood sugar control.
Who Shouldn't Take Tresiba FlexTouch?
- Hypoglycemia (low blood sugar)
- Known hypersensitivity to insulin degludec or any components of the formulation
Advice From The Pharmacist
- Tresiba FlexTouch should be injected subcutaneously in the abdomen, thigh, or upper arm. Rotate injection sites to avoid skin reactions.
- Store unused pens in the refrigerator, but once in use, they can be stored at room temperature and should be discarded after 8 weeks.
- Tresiba can be taken at any time of day but should be taken at the same time each day once a routine is established.
- Monitor your blood sugar regularly, especially when adjusting your dose or when changing your eating or physical activity levels.
Side Effects of Tresiba FlexTouch
Common Side Effects
- Hypoglycemia (low blood sugar)
- Injection site reactions (redness, swelling, or irritation)
- Weight gain
Uncommon/Severe Side Effects
- Severe hypoglycemia, which can lead to fainting, seizures, or coma
- Allergic reactions, including rash, swelling, or difficulty breathing
Risks and Warnings of Tresiba FlexTouch
- Hypoglycemia: Tresiba can cause dangerously low blood sugar, especially if taken in excess, skipped meals, or during intense physical activity. Regular blood sugar monitoring is essential.
- Hypokalemia: Insulin can lower potassium levels, leading to serious complications, including irregular heartbeats. Monitoring potassium levels may be necessary.
- Dosage Errors: Be cautious when using higher-concentration formulations to avoid overdose. Tresiba comes in both 100 units/mL and 200 units/mL, so ensure you're using the correct concentration.
Interactions with Tresiba FlexTouch
Common Drug Interactions
- Oral diabetes medications: Combining Tresiba with sulfonylureas or other oral diabetes drugs can increase the risk of hypoglycemia.
- Beta-blockers: These drugs can mask the symptoms of low blood sugar, making it harder to recognize hypoglycemia.
- Alcohol: Drinking alcohol can increase the risk of hypoglycemia and cause unpredictable blood sugar fluctuations.
Alternatives to Tresiba FlexTouch
- Lantus (insulin glargine): Another long-acting insulin that lasts for up to 24 hours, commonly used for type 1 and type 2 diabetes.
- Levemir (insulin detemir): A long-acting insulin used for blood sugar control over 24 hours.
- Toujeo (insulin glargine 300 units/mL): A more concentrated long-acting insulin, similar to Tresiba.
- Basaglar (insulin glargine): A biosimilar to Lantus for long-term blood sugar management.
