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NovoLOG Mix 70/30 ReliOn

NovoLOG Mix 70/30 ReliOn is a combination insulin product that contains 70% insulin aspart protamine (a longer-acting form) and 30% insulin aspart (a rapid-acting form). It is used for the management of diabetes mellitus in adults and children, helping to control blood glucose levels.

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Comprehensive Drug Guide

How Does NovoLOG Mix 70/30 ReliOn Work?

Insulin aspart works by facilitating the uptake of glucose into cells, reducing blood sugar levels. The protamine component prolongs the action of insulin aspart, providing both rapid and extended glucose control.



Common Dosages

  • Injection: Available in vials and prefilled pens, usually in concentrations of 100 units/mL.

Typical Dosing

  • Adults and Children: The dosage is individualized based on blood glucose levels, carbohydrate intake, and activity level. Dosing is usually administered subcutaneously before meals, with adjustments made as necessary.

Typical Dosing

FDA Approved Indications

  • Management of type 1 and type 2 diabetes mellitus.


Who Shouldn't Take NovoLOG Mix 70/30 ReliOn?

  • Known hypersensitivity to insulin aspart or any component of the formulation.
  • Severe hypoglycemia (low blood sugar).


Advice From The Pharmacist

  • Administer NovoLOG Mix 70/30 ReliOn exactly as prescribed, and do not exceed the recommended dose to avoid serious side effects.
  • Monitor blood glucose levels regularly to determine the correct dosage and adjust as necessary.
  • Be aware of the signs of hypoglycemia, which can include sweating, shaking, confusion, and irritability.


Side Effects of NovoLOG Mix 70/30 ReliOn

Common Side Effects

  • Hypoglycemia
  • Injection site reactions (redness, swelling, itching)
  • Weight gain


Uncommon/Severe Side Effects

  • Severe allergic reactions (anaphylaxis)
  • Hypoglycemia unawareness (not recognizing low blood sugar symptoms)


Risks and Warnings of NovoLOG Mix 70/30 ReliOn

  • Hypoglycemia Risk: Be vigilant about the potential for low blood sugar, especially if there are changes in diet, exercise, or other medications.
  • Insulin Overdose: Monitor dosing carefully to avoid hypoglycemic episodes, which can be serious.


Interactions with NovoLOG Mix 70/30 ReliOn

Common Drug Interactions

  • Other Diabetes Medications: Inform your healthcare provider about all medications you are taking, as other diabetes medications can affect blood glucose levels.
  • Certain Medications: Some drugs can affect insulin requirements and blood sugar control; communicate any changes to your healthcare provider.


Alternatives to NovoLOG Mix 70/30 ReliOn

  • Other Insulin Types: Such as insulin lispro or regular insulin for rapid-acting needs.
  • Oral Hypoglycemic Agents: For type 2 diabetes, options include metformin or sulfonylureas.