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Insulin Lispro

Insulin lispro is a type of medication that lowers levels of sugar (glucose) in the blood. It's a fastacting insulin that starts to work rapidly after injection and usually peaks in about 1 hour but keeps working for 2 to 4 hours. It's typically used with a medium or longacting insulin. Consistent usage can stabilize blood sugar levels. Possible side effects include weight gain, allergic reactions, and low blood sugar (hypoglycemia).

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Frequently Asked Questions

Can I take insulin lispro even if I have liver or kidney disease?
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Yes, but the dosage may need to be adjusted, so do consult your healthcare provider.

Can I switch to insulin lispro from another insulin type?
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Switching to another insulin type should only be done under supervision from a healthcare provider.

Does insulin lispro make you gain weight?
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Yes, one of the common side effects of insulin lispro is weight gain.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as possible unless it's time for the next dose. Do not double doses in case of missed doses.

Can I just stop taking insulin lispro?
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You must not stop taking insulin lispro unless directed by your healthcare provider.

Can I take alcohol while using insulin lispro?
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Drinking alcohol while using insulin lispro might lead to hypoglycemia, so it's best avoided.

Comprehensive Drug Guide

How Does Insulin Lispro Work?

Insulin lispro is a recombinant, fast-acting form of insulin that significantly helps diabetic patients maintain normal sugar levels. It promotes the cellular uptake of glucose and inhibits the output of glucose from the liver.

What is Insulin Lispro Used For?

Insulin Lispro is used to improve blood sugar control in adults and children with diabetes and other related metabolic disorders.

Common Dosages

Vials or Pens: 100 units/mL (Insulin Lispro), 200 units/mL (Lyumjev)

Typical Dosing

FDA Approved Indications

  • The dosage of insulin lispro is individualized and given by injection under the skin just before meals, to prevent an increase in blood sugar that occurs after eating.
  • Regular monitoring of blood glucose levels informs dosage adjustments.


Who Shouldn't Take Insulin Lispro?

  • People are allergic to insulin lispro or its other components.
  • People experience episodes of hypoglycemia (low blood sugar).
  • With liver or kidney impairment (dosage adjustment required).


Advice From The Pharmacist

  • Always measure your dosage accurately.
  • Paired with regular exercise and a balanced diet, insulin lispro can optimally manage your sugar levels.
  • Have quick sugar sources like candies or fruit juices handy in case of sudden dips in sugar levels.
  • Regularly monitoring your blood sugar levels is an absolute must.
  • It's vital to check your insulin for particles or discoloration. If present, do not use it.
  • Insulin lispro shouldn't be used during episodes of hypoglycemia.
  • Always rotate injection sites to avoid skin changes or lumps.


Side Effects of Insulin Lispro

Common Side Effects

  • Weight Gain
  • Hypoglycemia
  • Mild Skin Rash or Thickening at Injection Site.
  • Tingling


Uncommon/Severe Side Effects

  • Confusion
  • Anxiety
  • Feeling Shaky
  • Slurred Speech
  • Hunger
  • Dizziness
  • Fast Heartbeat
  • Sweating
  • Fainting or Unconsciousness.


Risks and Warnings of Insulin Lispro

  • Use with caution if you have liver or kidney problems; these conditions can affect how your body uses insulin lispro.
  • Regular monitoring of blood sugar is required when using insulin lispro.
  • Insulin lispro can cause low potassium, which could lead to leg cramps or irregular heartbeats.
  • You should avoid using insulin lispro during episodes of hypoglycemia (low blood sugar).


Interactions with Insulin Lispro

Common Drug Interactions

  • Pioglitazone
  • Rosiglitazone
  • Topiramate
  • Glucosamine
  • Some Fluoroquinolone Antibiotics


Alternatives to Insulin Lispro

  • Insulin Aspart
  • Insulin Glulisine
  • Regular Human Insulin