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HumaLOG
HumaLOG is the brand name for insulin lispro, a rapid-acting insulin used to control blood sugar levels in people with diabetes mellitus. It is primarily prescribed for individuals with both type 1 and type 2 diabetes and is used to manage blood glucose levels during meals. HumaLOG helps to mimic the natural insulin response to food intake, providing quick and effective glycemic control.
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Frequently Asked Questions
How quickly does HumaLOG work?
HumaLOG typically starts to lower blood sugar levels within 15 minutes after injection, peaking in about 1 to 2 hours.
Can I take HumaLOG with other diabetes medications?
Yes, HumaLOG can be used in combination with other diabetes medications, including oral hypoglycemics, but dosing adjustments may be necessary. Consult your healthcare provider for guidance.
What should I do if I miss a dose of HumaLOG?
If you miss a dose before a meal, take it as soon as you remember. If it’s close to your next meal, skip the missed dose and continue with your regular schedule. Do not double up on doses.
Is HumaLOG safe during pregnancy?
HumaLOG is considered safe to use during pregnancy, but it’s essential to discuss any treatment plans with your healthcare provider to ensure proper management of blood sugar levels.
Can I stop taking HumaLOG if my blood sugar levels improve?
It is important to continue using HumaLOG as prescribed, even if your blood sugar levels improve. Consult your healthcare provider before making any changes to your diabetes management plan.
Comprehensive Drug Guide
How Does HumaLOG Work?
Insulin lispro works by binding to insulin receptors on muscle and fat cells, facilitating the uptake of glucose from the bloodstream into these cells. It promotes the conversion of glucose to glycogen in the liver, thus lowering blood glucose levels. HumaLOG's rapid onset of action (typically within 15 minutes) makes it effective for controlling postprandial (after meal) blood sugar spikes.
Common Dosages
- Subcutaneous injection: Typically, 0.5 to 1.0 units/kg/day divided into multiple doses before meals.
- Adjustment: Doses may need to be adjusted based on blood glucose monitoring results and dietary intake.
Typical Dosing
- For blood glucose management: Administer HumaLOG 15 minutes before a meal. Dosing should be individualized based on the patient’s blood glucose monitoring and dietary intake.
Typical Dosing
FDA Approved Indications
- Management of diabetes mellitus in adults and children. It is used for the control of high blood sugar in both type 1 and type 2 diabetes.
Who Shouldn't Take HumaLOG?
- Known hypersensitivity to insulin lispro or any components of the formulation.
- Severe hypoglycemia: Individuals should not use HumaLOG if they are experiencing severe low blood sugar.
Advice From The Pharmacist
- Use as prescribed: Follow your healthcare provider's instructions regarding dosing, timing, and blood glucose monitoring.
- Monitor blood sugar: Regularly check your blood glucose levels to ensure they are within the target range, and adjust insulin doses accordingly.
- Store HumaLOG properly: Store unopened vials or pens in the refrigerator. Once opened, it can be kept at room temperature for up to 28 days. Avoid freezing.
- Inject with proper technique: Rotate injection sites to prevent lipodystrophy and ensure consistent absorption.
Side Effects of HumaLOG
Common Side Effects
- Hypoglycemia (low blood sugar)
- Injection site reactions (redness, swelling, itching)
- Weight gain
Uncommon/Severe Side Effects
- Severe allergic reactions (e.g., rash, itching, swelling, difficulty breathing)
- Insulin resistance with prolonged use or improper dosing.
Risks and Warnings of HumaLOG
- Hypoglycemia Risk: HumaLOG can cause low blood sugar, especially if meals are delayed or missed after injection. Patients should be educated on recognizing symptoms of hypoglycemia.
- Monitoring: Regular monitoring of blood glucose levels is essential to prevent hypoglycemia or hyperglycemia.
- Adjustments in illness: Illness, stress, or changes in diet may require adjustments to insulin doses.
Interactions with HumaLOG
Common Drug Interactions
- Oral hypoglycemic agents: Such as sulfonylureas, which may increase the risk of hypoglycemia when used concurrently.
- Beta-blockers: These may mask the symptoms of hypoglycemia and complicate its management.
Alternatives to HumaLOG
- Other rapid-acting insulins: Such as insulin aspart (Novolog) or insulin glulisine (Apidra).
- Long-acting insulins: Such as insulin glargine (Lantus) or insulin detemir (Levemir) for basal insulin needs.
