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HumuLIN R U-500 KwikPen
HumuLIN R U-500 KwikPen is an insulin formulation that provides a concentrated dose of regular human insulin. It is designed for patients with diabetes who require high doses of insulin and is often used in individuals with insulin resistance. The U-500 formulation allows for fewer injections while delivering a potent dose, making it a convenient option for managing blood sugar levels.
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Frequently Asked Questions
How quickly does HumuLIN R U-500 work?
The onset of action is typically within 30 minutes, with peak effects occurring in 2 to 4 hours.
Can I take HumuLIN R U-500 while pregnant?
Consult your healthcare provider for guidance, as insulin needs may change during pregnancy.
What should I do if I miss a dose?
If you miss a dose, take it as soon as you remember unless it's close to your next scheduled dose. Do not double up on doses.
Are there any specific storage instructions for HumuLIN R U-500?
Unused pens should be stored in the refrigerator. After opening, they can be stored at room temperature for up to 28 days.
Is HumuLIN R U-500 safe for long-term use?
Long-term use should be monitored by a healthcare provider to assess efficacy and manage any potential side effects.
Comprehensive Drug Guide
How Does HumuLIN R U-500 KwikPen Work?
HumuLIN R U-500 works by mimicking the action of natural insulin in the body. It promotes the uptake of glucose into muscle and fat cells while inhibiting glucose production in the liver. This action helps lower blood glucose levels, particularly after meals.
Common Dosages
- Pre-filled insulin pen: Each pen contains 300 units/mL, and patients can deliver doses in increments (e.g., 5 units, 10 units).
Typical Dosing
The typical dosing for HumuLIN R U-500 is:
- For Diabetes Management: Dosing is individualized based on the patient’s needs, blood glucose levels, and physician recommendations. It is typically injected subcutaneously before meals.
Typical Dosing
FDA Approved Indications
- Management of diabetes mellitus in patients who require high doses of insulin.
Who Shouldn't Take HumuLIN R U-500 KwikPen?
- Hypersensitivity: Known hypersensitivity to insulin or any components of the formulation.
- Severe Hypoglycemia: Should not be used in patients with low blood sugar levels.
Advice From The Pharmacist
- How to Use: Follow the dosing instructions provided by your healthcare provider. Ensure proper technique when using the pen for injections.
- Monitor Blood Glucose: Regularly check blood glucose levels to adjust dosing as needed.
- Storage: Store unused pens in the refrigerator. Once in use, the pen can be stored at room temperature for up to 28 days.
Side Effects of HumuLIN R U-500 KwikPen
Common Side Effects
- Hypoglycemia: Symptoms may include shaking, sweating, rapid heartbeat, and confusion.
- Injection site reactions: Such as redness, swelling, or pain at the injection site.
- Weight gain: Associated with insulin therapy.
Uncommon/Severe Side Effects
- Severe allergic reactions: Such as rash, itching, or difficulty breathing.
Risks and Warnings of HumuLIN R U-500 KwikPen
- Caution in Patients with Renal or Hepatic Impairment: Use with caution in patients with kidney or liver issues, as insulin clearance may be affected.
- Adjust Doses with Changes in Activity or Diet: Patients should be aware that changes in physical activity or dietary intake may necessitate dose adjustments.
Interactions with HumuLIN R U-500 KwikPen
Common Drug Interactions
- Drug Interactions: HumuLIN R U-500 may interact with other medications that affect blood glucose levels, including certain oral hypoglycemics and corticosteroids. Always inform your healthcare provider about all medications you are taking.
- Food Interactions: Food intake should be coordinated with insulin dosing to prevent hypoglycemia.
Alternatives to HumuLIN R U-500 KwikPen
- Other Insulin Preparations: Such as HumuLIN N (NPH insulin) or rapid-acting insulins for varying management needs.
- Oral Antidiabetic Agents: Such as metformin or sulfonylureas for type 2 diabetes.