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Fiasp PenFill
Fiasp PenFill is a fast-acting insulin aspart injection used to help control blood sugar levels in individuals with diabetes mellitus, including type 1 and type 2 diabetes. It is a mealtime insulin that works quickly to help manage blood sugar spikes that occur after eating. The PenFill version is a cartridge designed for use with reusable insulin delivery pens, making it convenient for individuals who need flexibility in their insulin administration.
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Frequently Asked Questions
How quickly does Fiasp PenFill start working?
Fiasp begins to lower blood sugar levels within 2 to 5 minutes after injection, making it faster than some other rapid-acting insulins.
Can Fiasp PenFill be used for Type 1 diabetes?
Yes, Fiasp is commonly used in people with Type 1 diabetes to control blood sugar spikes at mealtimes.
What should I do if I miss a dose of Fiasp PenFill?
If you forget to take your dose before a meal, you can inject it up to 20 minutes after starting your meal, based on your blood sugar readings and doctor’s advice.
Can I use Fiasp PenFill with other insulins?
Yes, Fiasp is often used in combination with long-acting insulin for basal control. However, it should not be mixed with other insulins in the same syringe.
What should I do if I experience low blood sugar?
If you experience hypoglycemia, take a fast-acting source of glucose, such as glucose tablets or juice, and check your blood sugar levels. If it’s very low, seek medical help immediately
Comprehensive Drug Guide
How Does Fiasp PenFill Work?
Fiasp (insulin aspart) works by replacing or supplementing the body's natural insulin. After injection, it quickly lowers blood glucose levels by helping glucose move from the bloodstream into cells where it can be used for energy. Fiasp is designed to start working within minutes of injection, making it ideal for controlling post-meal blood sugar spikes.
Common Dosages
- Injection immediately before meals, or up to 20 minutes after starting a meal, depending on blood glucose monitoring and doctor’s recommendations.
- Dosing is typically calculated in units of insulin, based on carbohydrate intake, current blood sugar levels, and other individual factors.
Typical Dosing
FDA Approved Indications
- Type 1 diabetes in adults and children to control blood sugar levels.
- Type 2 diabetes in adults to improve blood sugar control, especially around meals.
Pediatric Dosing
Advice From The Pharmacist
- Inject Fiasp PenFill immediately before eating or within 20 minutes after starting a meal, based on your blood sugar levels and doctor’s instructions.
- Monitor your blood sugar levels closely, especially when adjusting your insulin dose or diet.
- Rotate injection sites between the abdomen, thigh, and upper arm to prevent lipodystrophy (skin changes at injection sites).
- Be aware of the signs of hypoglycemia, including shakiness, sweating, dizziness, and confusion. Always keep a fast-acting source of glucose (like glucose tablets) with you.
- Store unused Fiasp cartridges in the refrigerator, but once in use, the cartridge can be stored at room temperature for up to 28 days.
Side Effects of Fiasp PenFill
Common Side Effects
- Low blood sugar (hypoglycemia)
- Injection site reactions (pain, redness, or swelling)
- Weight gain
- Skin thickening or pits at the injection site (lipodystrophy)
Uncommon/Severe Side Effects
- Severe hypoglycemia, which can cause seizures, unconsciousness, or death.
- Allergic reactions, such as rash, itching, swelling, or difficulty breathing.
- Hypokalemia (low potassium levels), which may cause irregular heartbeats.
Risks and Warnings of Fiasp PenFill
- Hypoglycemia: Fiasp may cause severe hypoglycemia, especially if administered without adequate food intake. Frequent blood glucose monitoring is essential, and patients should know how to manage low blood sugar.
- Hypokalemia: Insulin use can lead to low potassium levels, especially when combined with other medications that affect potassium levels.
- Weight Gain: Insulin therapy can contribute to weight gain, particularly when blood glucose is tightly controlled. Monitoring diet and exercise is important.
- Allergic Reactions: In rare cases, serious allergic reactions can occur. Seek medical help immediately if you experience difficulty breathing, swelling, or severe rash.
Interactions with Fiasp PenFill
Common Drug Interactions
- Oral diabetes medications: Fiasp can be used in combination with oral medications like metformin, but dosing may need to be adjusted.
- Beta-blockers: These medications can mask the symptoms of hypoglycemia, such as shakiness and increased heart rate.
- Alcohol: Drinking alcohol can increase the risk of hypoglycemia, especially when taken with insulin.
Alternatives to Fiasp PenFill
- NovoLog (insulin aspart): Another rapid-acting insulin, similar to Fiasp, used for mealtime blood sugar control.
- Humalog (insulin lispro): Another rapid-acting insulin analog used for controlling blood sugar spikes around meals.
- Apidra (insulin glulisine): Another rapid-acting insulin that starts working quickly to control post-meal blood sugar.
- Basaglar (insulin glargine): A long-acting insulin that may be used alongside Fiasp for basal insulin coverage.
