NiHowdy > Drug Classes > Antiemetics

Browse Medications by Drug Class: Antiemetics

Written by Amar Lunagaria

Pharm.D • NiHowdy Founder

Reviewed by James Wong

Pharm.D • NiHowdy Founder

Published Jan 15, 2025

Fact checked

What are Antiemetics?

Antiemetics are medications used to prevent or alleviate nausea and vomiting caused by various conditions, including motion sickness, chemotherapy, pregnancy, and gastrointestinal disorders. These medications work by targeting different pathways involved in the vomiting reflex, including the brain's vomiting center, gastrointestinal tract, and vestibular system. A unique characteristic of antiemetics is their ability to target specific causes of nausea, providing tailored relief for diverse conditions. NiHowdy ensures affordable access to antiemetics, empowering patients to manage nausea and vomiting effectively.

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List of drugs in Antiemetics

Drug Name	More Information	NiHowdy Prices & Bitcoin Rebate

Antivert	Antivert Information	Antivert Pricing
Bonjesta	Bonjesta Information	Bonjesta Pricing
Diclegis	Diclegis Information	Diclegis Pricing
dimenhyDRINATE	dimenhyDRINATE Information	dimenhyDRINATE Pricing
Doxylamine-Pyridoxine	Doxylamine-Pyridoxine Information	Doxylamine-Pyridoxine Pricing
Meclizine HCl	Meclizine HCl Information	Meclizine HCl Pricing
Promethegan	Promethegan Information	Promethegan Pricing
Sancuso	Sancuso Information	Sancuso Pricing
Tigan	Tigan Information	Tigan Pricing
Transderm Scop (1.5 MG)	Transderm Scop (1.5 MG) Information	Transderm Scop (1.5 MG) Pricing
Transderm-Scop	Transderm-Scop Information	Transderm-Scop Pricing
Trimethobenzamide HCl	Trimethobenzamide HCl Information	Trimethobenzamide HCl Pricing
Zofran	Zofran Information	Zofran Pricing
Zuplenz	Zuplenz Information	Zuplenz Pricing

Brief history about Antiemetics?

Antiemetics have evolved significantly since their initial use in the mid-20th century. Early antiemetics, such as promethazine, were developed to address motion sickness and postoperative nausea. Over time, newer classes like serotonin receptor antagonists (e.g., ondansetron) and neurokinin-1 receptor antagonists (e.g., aprepitant) were introduced, offering more targeted and effective relief, particularly for chemotherapy-induced nausea. Today, antiemetics are essential in managing nausea across a range of medical conditions. NiHowdy simplifies access to these medications, ensuring affordability for patients.

How do Antiemetics work?

Antiemetics work by blocking specific receptors involved in the vomiting reflex. For example, serotonin receptor antagonists like ondansetron block serotonin receptors in the gastrointestinal tract and brain, preventing signals that trigger nausea. Other antiemetics, such as dopamine antagonists or anticholinergics, target different pathways to provide relief. NiHowdy provides affordable access to antiemetics, ensuring patients receive effective treatment tailored to their condition.

What are Antiemetics used to treat?

Motion Sickness

Antiemetics like scopolamine and dimenhydrinate are effective in preventing nausea and vomiting caused by motion sickness during travel.

Gastrointestinal Disorders

Antiemetics like promethazine and prochlorperazine are used to manage nausea associated with gastrointestinal disorders such as gastritis, gastroenteritis, and gastroparesis.

Chemotherapy-Induced Nausea and Vomiting (CINV)

Medications like ondansetron and aprepitant are commonly used to prevent and manage nausea and vomiting caused by chemotherapy, helping patients tolerate treatment better.

Postoperative Nausea and Vomiting (PONV)

Antiemetics such as dexamethasone and metoclopramide are used to prevent nausea and vomiting following surgical procedures.

Pregnancy-Related Nausea (Morning Sickness)

For pregnancy-related nausea, medications like doxylamine and pyridoxine (Vitamin B6) are commonly used, while ondansetron may be prescribed in severe cases.

Who should consider Antiemetics medications?

Adults

Antiemetics are commonly prescribed for adults managing nausea and vomiting caused by chemotherapy, surgery, gastrointestinal disorders, or migraines. These medications provide targeted relief and improve quality of life. NiHowdy ensures adults can access these treatments affordably and conveniently.

Children

In pediatric cases, antiemetics may be used to treat nausea caused by gastroenteritis, motion sickness, or chemotherapy. Doses are carefully adjusted based on weight and age to ensure safety and efficacy. NiHowdy supports families with cost-effective solutions and reliable resources for managing pediatric nausea.

Seniors

Seniors with conditions like chemotherapy-induced nausea or vestibular disorders benefit significantly from antiemetics. However, older adults require careful monitoring for potential side effects, such as dizziness or confusion. NiHowdy simplifies access to antiemetics for seniors, offering affordable options tailored to their unique needs.

Are Antiemetics safe?

Antiemetics are generally safe when prescribed appropriately. Common side effects include drowsiness, dry mouth, and mild dizziness. Rare but serious risks include changes in heart rhythm (e.g., QT prolongation) or extrapyramidal symptoms with certain medications. Regular monitoring and adherence to prescribed doses minimize these risks. NiHowdy provides safe and affordable access to antiemetics, supported by expert guidance to manage these risks responsibly.

Can I take Antiemetics during pregnancy?

Certain antiemetics, such as doxylamine and pyridoxine, are considered safe during pregnancy for managing nausea and vomiting. Other medications, like ondansetron, may be prescribed in severe cases but require careful consideration of risks and benefits. Patients should consult their healthcare provider for personalized advice. NiHowdy provides cost-effective access to expert guidance and alternative treatments for pregnant patients.

Are Antiemetics safe to take while lactating?

The safety of antiemetics during lactation depends on the specific medication. Some antiemetics, like ondansetron, are considered compatible with breastfeeding, while others may require caution. Patients should consult their healthcare provider for specific recommendations. NiHowdy ensures affordable access to trusted information and safe treatment options for breastfeeding parents.

Are Antiemetics controlled substances?

Antiemetics are not classified as controlled substances but require a prescription for most formulations to ensure proper use and monitoring. NiHowdy simplifies the prescription process, ensuring patients receive these critical medications affordably and responsibly.

Side effects of Antiemetics?

Common side effects of antiemetics include drowsiness, dry mouth, constipation, and mild dizziness. Rare but serious risks include changes in heart rhythm (QT prolongation) or extrapyramidal symptoms with dopamine antagonists. Patients experiencing severe side effects should consult their healthcare provider immediately. NiHowdy helps patients manage these risks with expert-backed support and affordable care options.

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Cost considerations and insurance coverage for Antiemetics

The cost of antiemetics varies depending on the specific medication and formulation (e.g., oral, intravenous, or transdermal). Generic options like ondansetron and promethazine are generally affordable, and many insurance plans cover these medications for approved indications. NiHowdy offers discounts, rebates, and Bitcoin rewards to ensure these treatments remain accessible and cost-effective.

How do I get rebates on Antiemetics?

NiHowdy's Bitcoin rebate program for antiemetic prescriptions offers patients a unique opportunity to save on healthcare costs while earning potential financial growth. This innovative approach makes managing nausea and vomiting both affordable and rewarding, improving access to critical care while building long-term value.

Medical Conditions treated by Antiemetics

Nausea and Vomiting