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Transderm-Scop
Transderm-Scop is a prescription transdermal patch that contains scopolamine, an anticholinergic medication used to prevent nausea and vomiting associated with motion sickness and postoperative recovery. It works by blocking certain nerve signals to the brain, helping to control the feeling of nausea. The patch is applied to the skin, providing a slow and steady release of the medication over several days.
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Frequently Asked Questions
How long does the Transderm-Scop patch last?
Each patch lasts for 72 hours (3 days) and should be replaced after that time if continued use is needed.
Can I get the Transderm-Scop patch wet?
Yes, the patch is water-resistant, so you can wear it while swimming or showering. However, try to avoid excessive water exposure to prevent the patch from loosening.
Can I use Transderm-Scop if I wear contact lenses?
Scopolamine can cause blurred vision and dry eyes, which may make contact lens wear uncomfortable. Be cautious if you wear contact lenses while using the patch.
What should I do if the patch falls off?
If the patch falls off, apply a new one as soon as possible. Ensure the skin behind your ear is clean and dry before applying a replacement patch.
Can I take other anti-nausea medications with Transderm-Scop?
You should consult your doctor before combining Transderm-Scop with other anti-nausea medications, as this could increase the risk of side effects such as drowsiness or confusion.
Comprehensive Drug Guide
How Does Transderm-Scop Work?
Scopolamine, the active ingredient in Transderm-Scop, works by blocking the action of acetylcholine, a neurotransmitter in the nervous system. This helps to prevent nausea and vomiting by interfering with the communication between the nerves of the inner ear and the vomiting center in the brain. By reducing the activity of the vestibular system, which controls balance, scopolamine prevents motion sickness and helps manage nausea after surgery.
Common Dosages
- Transderm-Scop is available as a 1.5 mg transdermal patch, which releases scopolamine at a rate of 1 mg over a 3-day period (72 hours).
Typical Dosing
- For the prevention of motion sickness, apply one patch behind the ear at least 4 hours before travel.
- For postoperative nausea and vomiting, the patch is usually applied the evening before surgery and worn for up to 72 hours following the procedure.
- The patch should be replaced every 3 days if ongoing prevention is required.
Typical Dosing
FDA Approved Indications
- Prevention of nausea and vomiting associated with motion sickness.
- Prevention of postoperative nausea and vomiting (PONV) after anesthesia or surgery.
Who Shouldn't Take Transderm-Scop?
- Hypersensitivity to scopolamine or any components of the patch.
- Narrow-angle glaucoma, as anticholinergics can increase eye pressure.
Advice From The Pharmacist
- Apply the Transderm-Scop patch to a clean, dry, and hairless area of skin behind the ear. Press the patch firmly in place for a few seconds to ensure it adheres.
- Wash your hands after handling the patch to avoid accidentally transferring the medication to your eyes or mouth, which can cause side effects like blurred vision or dry mouth.
- Do not cut the patch, and avoid using more than one patch at a time.
- Remove the patch after 72 hours and replace it with a new one if continued use is needed. Be sure to rotate application sites to avoid skin irritation.
Side Effects of Transderm-Scop
Common Side Effects
- Dry mouth
- Blurred vision or dilated pupils
- Drowsiness
- Dizziness
- Disorientation or confusion (especially in older adults)
Uncommon/Severe Side Effects
- Severe allergic reactions (rash, itching, swelling)
- Eye pain or vision changes (due to increased intraocular pressure)
- Hallucinations or severe mood changes
Risks and Warnings of Transderm-Scop
- CNS Effects: Scopolamine may cause confusion, memory issues, or hallucinations, particularly in older adults. Use caution when operating heavy machinery or driving.
- Eye Pressure: Patients with narrow-angle glaucoma should not use Transderm-Scop, as it can increase intraocular pressure and worsen the condition.
- Heat Exposure: Avoid exposing the patch to excessive heat (like in saunas or hot tubs), as it can cause the patch to release more medication, increasing the risk of side effects.
Interactions with Transderm-Scop
Common Drug Interactions
- Alcohol: Combining scopolamine with alcohol can increase drowsiness and impair cognitive function.
- CNS depressants: Using other sedative medications, such as benzodiazepines or opioids, with scopolamine may increase drowsiness and the risk of CNS depression.
- Anticholinergic drugs: Combining with other anticholinergics can increase the risk of side effects like dry mouth, constipation, and confusion.
Alternatives to Transderm-Scop
- Meclizine (Antivert): An antihistamine commonly used for preventing motion sickness and vertigo.
- Dimenhydrinate (Dramamine): Another antihistamine used to prevent nausea and vomiting associated with motion sickness.
- Ondansetron (Zofran): A prescription antiemetic used to prevent nausea and vomiting from surgery or chemotherapy.
