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Meclizine HCl

Meclizine HCl is an antihistamine primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness. It is also used to manage symptoms of vertigo caused by inner ear problems. Meclizine works by blocking histamine receptors in the brain, which helps reduce the symptoms of motion sickness and vertigo.



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Frequently Asked Questions

How quickly does meclizine work for motion sickness?
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Meclizine typically starts to work within 1 hour after taking it, providing effective relief from motion sickness.

Can I take meclizine if I have allergies?
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Meclizine is an antihistamine and may help with allergy-related symptoms; however, consult your healthcare provider for specific recommendations.

What should I do if I miss a dose?
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If you miss a dose, take it as soon as you remember. If it’s close to your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double up doses.

Are there any dietary restrictions while taking meclizine?
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There are no specific dietary restrictions, but it’s advisable to avoid alcohol while taking meclizine due to increased sedative effects.

Is it safe to use meclizine during pregnancy or breastfeeding?
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Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits of using meclizine.

Comprehensive Drug Guide

How Does Meclizine HCl Work?

Meclizine works by selectively blocking H1 histamine receptors in the central nervous system. This action reduces the effects of histamine, which is involved in the regulation of balance and nausea. By inhibiting these receptors, meclizine helps prevent the symptoms associated with motion sickness and vertigo.



Common Dosages

  • Tablets: 12.5 mg, 25 mg, and 50 mg.

Typical Dosing

  • For motion sickness: The usual dose is 25 mg to 50 mg taken at least one hour before travel.
  • For vertigo: The recommended dose is usually 25 mg to 100 mg per day, divided into multiple doses.


Typical Dosing

FDA Approved Indications

  • Prevention and treatment of motion sickness.
  • Management of vertigo associated with inner ear conditions.


Who Shouldn't Take Meclizine HCl?

  • Known hypersensitivity to meclizine or any component of the formulation.
  • Acute asthma attacks or severe respiratory problems.


Advice From The Pharmacist

  • Take meclizine with or without food as directed, preferably 1 hour before travel for motion sickness.
  • Avoid activities that require mental alertness, such as driving or operating heavy machinery, until you know how meclizine affects you.
  • Inform your healthcare provider of any other medications you are taking to avoid potential interactions.


Side Effects of Meclizine HCl

Common Side Effects

  • Drowsiness or sedation
  • Dry mouth
  • Fatigue
  • Dizziness


Uncommon/Severe Side Effects

  • Severe allergic reactions (rash, itching, swelling)
  • Fast or irregular heartbeat


Risks and Warnings of Meclizine HCl

  • Sedation Risk: Meclizine can cause drowsiness; caution should be taken, especially when combined with other sedatives or alcohol.
  • Anticholinergic Effects: May cause dry mouth, blurred vision, or urinary retention in susceptible individuals.
  • Use in Pregnancy: Consult your healthcare provider if you are pregnant or breastfeeding to discuss the risks and benefits.


Interactions with Meclizine HCl

Common Drug Interactions

  • CNS Depressants: The sedative effects may be enhanced when taken with other central nervous system depressants, such as alcohol, benzodiazepines, and opioids.
  • Other Antihistamines: Caution is advised when combining with other antihistamines due to increased risk of side effects.


Alternatives to Meclizine HCl

  • Other Antihistamines: Such as diphenhydramine or dimenhydrinate for motion sickness.
  • Prescription Medications: Such as scopolamine patches for motion sickness or vertigo management.